Predicted complex interactions
CCL20_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL20_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 115
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm31 | GLU 198 | 45.51x51 | VdWContact |
| ALA 1 | NTc.Cm31 | LYS 298 | 7.35x34 | Hydrophobic |
| ALA 1 | NTc.Cm31 | GLU 302 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm31 | GLU 302 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm31 | GLU 302 | 7.39x38 | VdWContact |
| SER 2 | NTc.Cm30 | GLU 198 | 45.51x51 | HBDonor |
| SER 2 | NTc.Cm30 | GLU 198 | 45.51x51 | VdWContact |
| ASN 3 | NTc.Cm29 | LEU 38 | - | Hydrophobic |
| ASN 3 | NTc.Cm29 | VAL 41 | 1.27x27 | Hydrophobic |
| ASN 3 | NTc.Cm29 | VAL 41 | 1.27x27 | VdWContact |
| ASN 3 | NTc.Cm29 | ARG 42 | 1.28x28 | HBAcceptor |
| ASN 3 | NTc.Cm29 | ARG 42 | 1.28x28 | Hydrophobic |
| ASN 3 | NTc.Cm29 | ARG 42 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm28 | LEU 38 | - | VdWContact |
| PHE 4 | NTc.Cm28 | THR 191 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | THR 191 | - | VdWContact |
| PHE 4 | NTc.Cm28 | GLN 192 | - | VdWContact |
| PHE 4 | NTc.Cm28 | VAL 196 | - | Hydrophobic |
| PHE 4 | NTc.Cm28 | VAL 196 | - | VdWContact |
| PHE 4 | NTc.Cm28 | GLU 198 | 45.51x51 | Hydrophobic |
| ASP 5 | NTc.Cm27 | LEU 35 | - | Hydrophobic |
| ASP 5 | NTc.Cm27 | LEU 35 | - | VdWContact |
| ASP 5 | NTc.Cm27 | CYS 36 | - | VdWContact |
| ASP 5 | NTc.Cm27 | SER 37 | - | VdWContact |
| ASP 5 | NTc.Cm27 | LEU 38 | - | HBAcceptor |
| ASP 5 | NTc.Cm27 | LEU 38 | - | VdWContact |
| ASP 5 | NTc.Cm27 | ARG 42 | 1.28x28 | Anionic |
| ASP 5 | NTc.Cm27 | ARG 42 | 1.28x28 | HBAcceptor |
| ASP 5 | NTc.Cm27 | ARG 42 | 1.28x28 | VdWContact |
| ASP 5 | NTc.Cm27 | GLN 192 | - | HBAcceptor |
| ASP 5 | NTc.Cm27 | GLN 192 | - | HBDonor |
| ASP 5 | NTc.Cm27 | GLN 192 | - | VdWContact |
| CYS 6 | NTc.Cm26 | LEU 35 | - | VdWContact |
| CYS 6 | NTc.Cm26 | CYS 36 | - | HBAcceptor |
| CYS 6 | NTc.Cm26 | CYS 36 | - | HBDonor |
| CYS 6 | NTc.Cm26 | CYS 36 | - | VdWContact |
| LEU 8 | NTc.Cm24 | CYS 36 | - | Hydrophobic |
| LEU 8 | NTc.Cm24 | MET 284 | 6.65x65 | VdWContact |
| LEU 8 | NTc.Cm24 | ARG 286 | - | Hydrophobic |
| LEU 8 | NTc.Cm24 | CYS 288 | 7.25x24 | Hydrophobic |
| LEU 8 | NTc.Cm24 | GLU 291 | 7.28x27 | Hydrophobic |
| LEU 8 | NTc.Cm24 | GLU 291 | 7.28x27 | VdWContact |
| TYR 10 | NTc.Cm22 | MET 284 | 6.65x65 | Hydrophobic |
| TYR 10 | NTc.Cm22 | MET 284 | 6.65x65 | VdWContact |
| THR 11 | NTc.Cm21 | MET 33 | - | VdWContact |
| ASP 12 | NTc.Cm20 | MET 33 | - | Hydrophobic |
| ASP 12 | NTc.Cm20 | MET 33 | - | VdWContact |
| ARG 13 | NTc.Cm19 | TYR 27 | - | VdWContact |
| ILE 14 | NTc.Cm18 | TYR 18 | - | Hydrophobic |
| ILE 14 | NTc.Cm18 | PHE 19 | - | Hydrophobic |
| ILE 14 | NTc.Cm18 | VAL 22 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | PHE 19 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | PHE 19 | - | VdWContact |
| HIS 16 | NTc.Cm16 | VAL 22 | - | Hydrophobic |
| HIS 16 | NTc.Cm16 | THR 24 | - | Hydrophobic |
| PRO 17 | NTc.Cm15 | PHE 19 | - | Hydrophobic |
| PRO 17 | NTc.Cm15 | PHE 19 | - | VdWContact |
| PHE 19 | NTc.Cm13 | THR 24 | - | Hydrophobic |
| PHE 19 | NTc.Cm13 | THR 24 | - | VdWContact |
| PHE 19 | NTc.Cm13 | TYR 26 | - | Hydrophobic |
| PHE 19 | NTc.Cm13 | TYR 26 | - | VdWContact |
| ALA 28 | NTc.Cm4 | PRO 207 | 5.31x32 | Hydrophobic |
| ALA 28 | NTc.Cm4 | LYS 211 | 5.35x36 | HBAcceptor |
| ALA 28 | NTc.Cm4 | LYS 211 | 5.35x36 | VdWContact |
| ASN 29 | NTc.Cm3 | LYS 200 | - | VdWContact |
| ASN 29 | NTc.Cm3 | TYR 201 | - | HBAcceptor |
| ASN 29 | NTc.Cm3 | TYR 201 | - | HBDonor |
| ASN 29 | NTc.Cm3 | TYR 201 | - | Hydrophobic |
| ASN 29 | NTc.Cm3 | TYR 201 | - | VdWContact |
| ASN 29 | NTc.Cm3 | PRO 207 | 5.31x32 | Hydrophobic |
| GLU 30 | NTc.Cm2 | TYR 189 | - | Hydrophobic |
| GLU 30 | NTc.Cm2 | THR 191 | - | HBAcceptor |
| GLU 30 | NTc.Cm2 | THR 191 | - | VdWContact |
| GLU 30 | NTc.Cm2 | LYS 200 | - | Anionic |
| GLU 30 | NTc.Cm2 | LYS 200 | - | HBAcceptor |
| GLU 30 | NTc.Cm2 | LYS 200 | - | Hydrophobic |
| GLU 30 | NTc.Cm2 | LYS 200 | - | VdWContact |
| GLU 30 | NTc.Cm2 | LYS 211 | 5.35x36 | VdWContact |
| GLY 31 | NTc.Cm1 | LYS 211 | 5.35x36 | HBAcceptor |
| GLY 31 | NTc.Cm1 | LYS 211 | 5.35x36 | VdWContact |
| CYS 32 | CX.1 | LYS 211 | 5.35x36 | HBAcceptor |
| CYS 32 | CX.1 | LYS 211 | 5.35x36 | VdWContact |
| ASP 33 | CX.5 | LYS 211 | 5.35x36 | Anionic |
| ASP 33 | CX.5 | LYS 211 | 5.35x36 | HBAcceptor |
| ASP 33 | CX.5 | LYS 211 | 5.35x36 | VdWContact |
| ASP 33 | CX.5 | LEU 281 | 6.62x62 | VdWContact |
| ASP 33 | CX.5 | GLY 282 | 6.63x63 | VdWContact |
| ASP 33 | CX.5 | ARG 286 | - | Anionic |
| ASP 33 | CX.5 | ARG 286 | - | HBAcceptor |
| ASP 33 | CX.5 | ARG 286 | - | VdWContact |
| ILE 34 | cxb1.1 | MET 284 | 6.65x65 | Hydrophobic |
| ILE 38 | cxb1.7 | LEU 35 | - | Hydrophobic |
| THR 41 | cxb1.11 | TYR 26 | - | VdWContact |
| LYS 42 | cxb1.14 | TYR 26 | - | VdWContact |
| LYS 43 | cxb1.15 | TYR 26 | - | HBDonor |
| LYS 43 | cxb1.15 | TYR 26 | - | Hydrophobic |
| LYS 43 | cxb1.15 | TYR 26 | - | VdWContact |
| LEU 45 | B1.1 | LEU 34 | - | Hydrophobic |
| SER 46 | B1.2 | LEU 35 | - | HBAcceptor |
| SER 46 | B1.2 | LEU 35 | - | VdWContact |
| VAL 47 | B1.3 | VAL 29 | - | Hydrophobic |
| VAL 47 | B1.3 | LEU 34 | - | Hydrophobic |
| CYS 48 | B1.4 | MET 33 | - | HBDonor |
| CYS 48 | B1.4 | MET 33 | - | VdWContact |
| THR 54 | b1b2.7 | TYR 18 | - | HBDonor |
| THR 54 | b1b2.7 | TYR 18 | - | VdWContact |
| TRP 55 | b1b2.8 | TYR 18 | - | Hydrophobic |
| TRP 55 | b1b2.8 | PHE 19 | - | Hydrophobic |
| TYR 58 | b1b2.12 | SER 15 | - | VdWContact |
| TYR 58 | b1b2.12 | PHE 19 | - | Hydrophobic |
| TYR 58 | b1b2.12 | PHE 19 | - | VdWContact |
| ILE 59 | b1b2.13 | PHE 19 | - | Hydrophobic |
| LEU 62 | B2.1 | PHE 12 | - | Hydrophobic |
| LYS 65 | B2.4 | PHE 12 | - | Hydrophobic |
| LYS 65 | B2.4 | PHE 12 | - | VdWContact |
