Predicted complex interactions
CCL21_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 87
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | TRP 102 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm30 | LYS 298 | 7.35x34 | VdWContact |
| SER 1 | NTc.Cm30 | GLU 302 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 302 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 302 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | VAL 196 | - | VdWContact |
| ASP 2 | NTc.Cm29 | GLU 198 | 45.51x51 | HBDonor |
| ASP 2 | NTc.Cm29 | GLU 198 | 45.51x51 | Hydrophobic |
| ASP 2 | NTc.Cm29 | GLU 198 | 45.51x51 | VdWContact |
| GLY 3 | NTc.Cm28 | GLY 109 | 2.67x67 | VdWContact |
| GLY 4 | NTc.Cm27 | ARG 42 | 1.28x28 | VdWContact |
| ALA 5 | NTc.Cm26 | LEU 38 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | LEU 38 | - | VdWContact |
| ALA 5 | NTc.Cm26 | VAL 41 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm26 | ARG 42 | 1.28x28 | HBAcceptor |
| ALA 5 | NTc.Cm26 | ARG 42 | 1.28x28 | VdWContact |
| GLN 6 | NTc.Cm25 | LEU 38 | - | VdWContact |
| GLN 6 | NTc.Cm25 | THR 191 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LEU 35 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | LEU 35 | - | VdWContact |
| ASP 7 | NTc.Cm24 | CYS 36 | - | VdWContact |
| ASP 7 | NTc.Cm24 | SER 37 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | SER 37 | - | VdWContact |
| ASP 7 | NTc.Cm24 | LEU 38 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | LEU 38 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ARG 42 | 1.28x28 | Anionic |
| ASP 7 | NTc.Cm24 | ARG 42 | 1.28x28 | HBAcceptor |
| ASP 7 | NTc.Cm24 | ARG 42 | 1.28x28 | VdWContact |
| ASP 7 | NTc.Cm24 | GLN 192 | - | HBAcceptor |
| ASP 7 | NTc.Cm24 | GLN 192 | - | HBDonor |
| ASP 7 | NTc.Cm24 | GLN 192 | - | VdWContact |
| CYS 8 | NTc.Cm23 | LEU 35 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 36 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 36 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 36 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | ARG 286 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 288 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm21 | GLU 291 | 7.28x27 | Hydrophobic |
| LEU 10 | NTc.Cm21 | GLU 291 | 7.28x27 | VdWContact |
| LYS 11 | NTc.Cm20 | GLU 32 | - | Cationic |
| LYS 11 | NTc.Cm20 | GLU 32 | - | HBDonor |
| LYS 11 | NTc.Cm20 | GLU 32 | - | Hydrophobic |
| LYS 11 | NTc.Cm20 | GLU 32 | - | VdWContact |
| LYS 11 | NTc.Cm20 | ASN 285 | - | VdWContact |
| LYS 11 | NTc.Cm20 | ARG 286 | - | VdWContact |
| TYR 12 | NTc.Cm19 | MET 284 | 6.65x65 | Hydrophobic |
| SER 13 | NTc.Cm18 | MET 33 | - | VdWContact |
| GLN 14 | NTc.Cm17 | MET 33 | - | Hydrophobic |
| GLN 14 | NTc.Cm17 | MET 33 | - | VdWContact |
| ARG 15 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| LYS 16 | NTc.Cm15 | TYR 27 | - | VdWContact |
| PRO 18 | NTc.Cm13 | PHE 19 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | TYR 27 | - | Hydrophobic |
| LYS 20 | NTc.Cm11 | VAL 22 | - | VdWContact |
| GLU 29 | NTc.Cm2 | LYS 200 | - | Anionic |
| PRO 30 | NTc.Cm1 | THR 203 | - | Hydrophobic |
| PRO 30 | NTc.Cm1 | THR 203 | - | VdWContact |
| SER 31 | CX.1 | LEU 281 | 6.62x62 | VdWContact |
| LEU 32 | CX.5 | GLU 198 | 45.51x51 | VdWContact |
| LEU 32 | CX.5 | PRO 199 | 45.52x52 | Hydrophobic |
| LEU 32 | CX.5 | PRO 199 | 45.52x52 | VdWContact |
| LEU 32 | CX.5 | TYR 201 | - | Hydrophobic |
| LEU 32 | CX.5 | TYR 201 | - | VdWContact |
| LEU 32 | CX.5 | THR 277 | 6.58x58 | Hydrophobic |
| SER 35 | cxb1.5 | LEU 281 | 6.62x62 | VdWContact |
| SER 35 | cxb1.5 | GLY 282 | 6.63x63 | HBAcceptor |
| SER 35 | cxb1.5 | GLY 282 | 6.63x63 | VdWContact |
| SER 35 | cxb1.5 | LYS 283 | 6.64x64 | HBDonor |
| SER 35 | cxb1.5 | LYS 283 | 6.64x64 | VdWContact |
| SER 35 | cxb1.5 | ARG 286 | - | VdWContact |
| ILE 36 | cxb1.6 | MET 284 | 6.65x65 | Hydrophobic |
| ILE 36 | cxb1.6 | MET 284 | 6.65x65 | VdWContact |
| LEU 40 | cxb1.11 | LEU 35 | - | Hydrophobic |
| ALA 49 | B1.6 | LEU 34 | - | Hydrophobic |
| ALA 49 | B1.6 | LEU 34 | - | VdWContact |
| GLU 50 | B1.7 | LEU 35 | - | HBAcceptor |
| GLU 50 | B1.7 | LEU 35 | - | Hydrophobic |
| GLU 50 | B1.7 | LEU 35 | - | VdWContact |
| LEU 51 | b1b2.4 | VAL 29 | - | Hydrophobic |
| LEU 51 | b1b2.4 | VAL 29 | - | VdWContact |
| CYS 52 | b1b2.6 | MET 33 | - | HBDonor |
| CYS 52 | b1b2.6 | MET 33 | - | VdWContact |
| LYS 75 | B3.3 | ASN 190 | - | HBDonor |
| LYS 75 | B3.3 | ASN 190 | - | VdWContact |
| LYS 75 | B3.3 | GLN 192 | - | VdWContact |
| LYS 75 | B3.3 | GLY 193 | - | HBDonor |
| LYS 75 | B3.3 | GLY 193 | - | VdWContact |
