Predicted complex interactions
CCL22_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TYR 53 | 1.39x39 | VdWContact |
| GLY 1 | NTc.Cm35 | HIS 106 | 2.64x64 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 302 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 302 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLU 302 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | LYS 122 | 3.29x29 | HBAcceptor |
| PRO 2 | NTc.Cm34 | LYS 122 | 3.29x29 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LYS 122 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 125 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | GLU 302 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm34 | GLU 302 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 306 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm34 | PHE 306 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 274 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 274 | 6.55x55 | VdWContact |
| TYR 3 | NTc.Cm33 | LYS 298 | 7.35x34 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 302 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 302 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | LYS 298 | 7.35x34 | HBAcceptor |
| GLY 4 | NTc.Cm32 | LYS 298 | 7.35x34 | VdWContact |
| ALA 5 | NTc.Cm31 | VAL 41 | 1.27x27 | Hydrophobic |
| ASN 6 | NTc.Cm30 | GLU 198 | 45.51x51 | VdWContact |
| MET 7 | NTc.Cm29 | ARG 42 | 1.28x28 | VdWContact |
| MET 7 | NTc.Cm29 | VAL 196 | - | Hydrophobic |
| MET 7 | NTc.Cm29 | VAL 196 | - | VdWContact |
| MET 7 | NTc.Cm29 | GLU 198 | 45.51x51 | HBDonor |
| MET 7 | NTc.Cm29 | GLU 198 | 45.51x51 | VdWContact |
| GLU 8 | NTc.Cm28 | TYR 189 | - | HBAcceptor |
| GLU 8 | NTc.Cm28 | TYR 189 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | TYR 189 | - | VdWContact |
| GLU 8 | NTc.Cm28 | THR 191 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | LYS 211 | 5.35x36 | Anionic |
| SER 10 | NTc.Cm26 | LEU 35 | - | VdWContact |
| SER 10 | NTc.Cm26 | LEU 38 | - | VdWContact |
| VAL 11 | NTc.Cm25 | GLN 192 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | GLN 192 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 32 | - | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 32 | - | VdWContact |
| ARG 14 | NTc.Cm22 | LEU 34 | - | HBDonor |
| ARG 14 | NTc.Cm22 | LEU 34 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 36 | - | VdWContact |
| ARG 14 | NTc.Cm22 | MET 284 | 6.65x65 | VdWContact |
| ARG 14 | NTc.Cm22 | ASN 285 | - | HBAcceptor |
| ARG 14 | NTc.Cm22 | ASN 285 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ARG 286 | - | HBDonor |
| ARG 14 | NTc.Cm22 | ARG 286 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | ARG 286 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 291 | 7.28x27 | VdWContact |
| TYR 16 | NTc.Cm20 | MET 284 | 6.65x65 | Hydrophobic |
| TYR 16 | NTc.Cm20 | MET 284 | 6.65x65 | VdWContact |
| VAL 17 | NTc.Cm19 | MET 33 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | MET 33 | - | VdWContact |
| ARG 18 | NTc.Cm18 | MET 33 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TYR 27 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | VAL 29 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | VAL 29 | - | VdWContact |
| TYR 19 | NTc.Cm17 | MET 33 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 27 | - | VdWContact |
| ARG 24 | NTc.Cm12 | PHE 19 | - | CationPi |
| ARG 24 | NTc.Cm12 | PHE 19 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| TYR 30 | NTc.Cm6 | GLN 192 | - | VdWContact |
| ASP 34 | NTc.Cm2 | THR 203 | - | Hydrophobic |
| ASP 34 | NTc.Cm2 | THR 203 | - | VdWContact |
| SER 35 | NTc.Cm1 | LYS 211 | 5.35x36 | HBAcceptor |
| SER 35 | NTc.Cm1 | LYS 211 | 5.35x36 | VdWContact |
| PRO 37 | CX.5 | ILE 208 | 5.32x33 | Hydrophobic |
| PRO 37 | CX.5 | ILE 208 | 5.32x33 | VdWContact |
| PRO 37 | CX.5 | GLY 282 | 6.63x63 | VdWContact |
| ARG 38 | cxb1.1 | MET 284 | 6.65x65 | VdWContact |
| VAL 42 | cxb1.7 | LEU 35 | - | Hydrophobic |
| VAL 42 | cxb1.7 | LEU 35 | - | VdWContact |
| LYS 49 | B1.1 | VAL 29 | - | Hydrophobic |
| LYS 49 | B1.1 | LEU 34 | - | Hydrophobic |
| LYS 49 | B1.1 | LEU 34 | - | VdWContact |
| GLU 50 | B1.2 | LEU 34 | - | VdWContact |
| GLU 50 | B1.2 | LEU 35 | - | HBAcceptor |
| GLU 50 | B1.2 | LEU 35 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 35 | - | VdWContact |
| ILE 51 | B1.3 | VAL 29 | - | Hydrophobic |
| ILE 51 | B1.3 | LEU 34 | - | Hydrophobic |
| CYS 52 | B1.4 | MET 33 | - | HBDonor |
| CYS 52 | B1.4 | MET 33 | - | VdWContact |
| CYS 52 | B1.4 | LEU 35 | - | VdWContact |
