Predicted complex interactions
CCL25_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 101
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 102 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TRP 102 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm29 | HIS 106 | 2.64x64 | VdWContact |
| GLN 1 | NTc.Cm29 | LYS 122 | 3.29x29 | HBAcceptor |
| GLN 1 | NTc.Cm29 | LYS 122 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 302 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 302 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 302 | 7.39x38 | VdWContact |
| GLN 1 | NTc.Cm29 | PHE 306 | 7.43x42 | VdWContact |
| GLY 2 | NTc.Cm28 | GLU 198 | 45.51x51 | VdWContact |
| VAL 3 | NTc.Cm27 | ARG 42 | 1.28x28 | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLY 109 | 2.67x67 | VdWContact |
| VAL 3 | NTc.Cm27 | VAL 196 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | LEU 38 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 41 | 1.27x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ARG 42 | 1.28x28 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ARG 42 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm26 | LYS 298 | 7.35x34 | Hydrophobic |
| GLU 5 | NTc.Cm25 | LEU 38 | - | VdWContact |
| GLU 5 | NTc.Cm25 | THR 191 | - | HBAcceptor |
| GLU 5 | NTc.Cm25 | THR 191 | - | Hydrophobic |
| GLU 5 | NTc.Cm25 | THR 191 | - | VdWContact |
| ASP 6 | NTc.Cm24 | SER 37 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LEU 38 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | LEU 38 | - | VdWContact |
| ASP 6 | NTc.Cm24 | ARG 42 | 1.28x28 | Anionic |
| ASP 6 | NTc.Cm24 | ARG 42 | 1.28x28 | HBAcceptor |
| ASP 6 | NTc.Cm24 | ARG 42 | 1.28x28 | VdWContact |
| ASP 6 | NTc.Cm24 | GLN 192 | - | HBAcceptor |
| ASP 6 | NTc.Cm24 | GLN 192 | - | HBDonor |
| ASP 6 | NTc.Cm24 | GLN 192 | - | VdWContact |
| CYS 7 | NTc.Cm23 | LEU 35 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 36 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 36 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 36 | - | VdWContact |
| CYS 8 | NTc.Cm22 | LEU 34 | - | VdWContact |
| CYS 8 | NTc.Cm22 | LEU 35 | - | VdWContact |
| LEU 9 | NTc.Cm21 | LEU 34 | - | HBDonor |
| LEU 9 | NTc.Cm21 | LEU 34 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 36 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 36 | - | VdWContact |
| LEU 9 | NTc.Cm21 | MET 284 | 6.65x65 | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 288 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | GLU 291 | 7.28x27 | Hydrophobic |
| LEU 9 | NTc.Cm21 | GLU 291 | 7.28x27 | VdWContact |
| ALA 10 | NTc.Cm20 | LEU 34 | - | Hydrophobic |
| ALA 10 | NTc.Cm20 | LEU 34 | - | VdWContact |
| ALA 10 | NTc.Cm20 | MET 284 | 6.65x65 | Hydrophobic |
| ALA 10 | NTc.Cm20 | MET 284 | 6.65x65 | VdWContact |
| TYR 11 | NTc.Cm19 | MET 284 | 6.65x65 | Hydrophobic |
| TYR 11 | NTc.Cm19 | MET 284 | 6.65x65 | VdWContact |
| HIS 12 | NTc.Cm18 | SER 31 | - | VdWContact |
| HIS 12 | NTc.Cm18 | LEU 34 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | LEU 34 | - | VdWContact |
| PRO 14 | NTc.Cm16 | TYR 27 | - | HBAcceptor |
| PRO 14 | NTc.Cm16 | TYR 27 | - | VdWContact |
| ALA 18 | NTc.Cm12 | VAL 20 | - | Hydrophobic |
| ARG 21 | NTc.Cm9 | GLU 16 | - | Cationic |
| ARG 21 | NTc.Cm9 | GLU 16 | - | HBDonor |
| ARG 21 | NTc.Cm9 | GLU 16 | - | VdWContact |
| ARG 22 | NTc.Cm8 | ASP 17 | - | Cationic |
| ARG 22 | NTc.Cm8 | VAL 20 | - | VdWContact |
| ARG 27 | NTc.Cm3 | THR 191 | - | HBDonor |
| ARG 27 | NTc.Cm3 | THR 191 | - | VdWContact |
| ARG 27 | NTc.Cm3 | GLN 192 | - | VdWContact |
| GLU 30 | CX.1 | LYS 200 | - | Anionic |
| GLU 30 | CX.1 | LYS 200 | - | HBAcceptor |
| GLU 30 | CX.1 | LYS 200 | - | VdWContact |
| GLU 30 | CX.1 | GLN 202 | - | Hydrophobic |
| GLU 30 | CX.1 | GLN 202 | - | VdWContact |
| VAL 31 | CX.5 | TYR 201 | - | Hydrophobic |
| VAL 31 | CX.5 | TYR 201 | - | VdWContact |
| VAL 31 | CX.5 | PRO 207 | 5.31x32 | Hydrophobic |
| VAL 31 | CX.5 | PRO 207 | 5.31x32 | VdWContact |
| VAL 31 | CX.5 | ILE 208 | 5.32x33 | Hydrophobic |
| VAL 31 | CX.5 | LYS 211 | 5.35x36 | Hydrophobic |
| VAL 31 | CX.5 | LYS 211 | 5.35x36 | VdWContact |
| SER 32 | cxb1.1 | TYR 189 | - | VdWContact |
| SER 32 | cxb1.1 | PRO 199 | 45.52x52 | VdWContact |
| SER 32 | cxb1.1 | LYS 211 | 5.35x36 | HBAcceptor |
| SER 32 | cxb1.1 | LYS 211 | 5.35x36 | VdWContact |
| GLY 33 | cxb1.2 | GLU 198 | 45.51x51 | HBDonor |
| GLY 33 | cxb1.2 | GLU 198 | 45.51x51 | VdWContact |
| SER 34 | cxb1.5 | GLU 198 | 45.51x51 | HBDonor |
| SER 34 | cxb1.5 | GLU 198 | 45.51x51 | VdWContact |
| ASN 36 | cxb1.8 | LYS 211 | 5.35x36 | HBAcceptor |
| ASN 36 | cxb1.8 | LYS 211 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | THR 277 | 6.58x58 | VdWContact |
| ASN 36 | cxb1.8 | LEU 281 | 6.62x62 | Hydrophobic |
| ASN 36 | cxb1.8 | GLY 282 | 6.63x63 | HBAcceptor |
| ASN 36 | cxb1.8 | GLY 282 | 6.63x63 | VdWContact |
| ASN 36 | cxb1.8 | ARG 286 | - | VdWContact |
| LEU 37 | cxb1.10 | MET 284 | 6.65x65 | Hydrophobic |
| PRO 38 | cxb1.11 | ILE 208 | 5.32x33 | Hydrophobic |
| ILE 41 | cxb1.16 | LEU 35 | - | Hydrophobic |
| ARG 49 | b1b2.1 | THR 24 | - | HBDonor |
| ARG 49 | b1b2.1 | THR 24 | - | VdWContact |
| ARG 49 | b1b2.1 | SER 28 | - | VdWContact |
| LYS 50 | b1b2.2 | LEU 35 | - | Hydrophobic |
| LYS 50 | b1b2.2 | LEU 35 | - | VdWContact |
| LYS 56 | b1b2.9 | GLU 206 | - | Cationic |
