Predicted complex interactions
CCL28_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 113
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm29 | GLU 218 | 5.42x43 | Cationic |
| SER 1 | NTc.Cm29 | GLU 218 | 5.42x43 | HBDonor |
| SER 1 | NTc.Cm29 | GLU 218 | 5.42x43 | VdWContact |
| GLU 2 | NTc.Cm28 | LEU 215 | 5.39x40 | Hydrophobic |
| GLU 2 | NTc.Cm28 | GLU 218 | 5.42x43 | HBDonor |
| GLU 2 | NTc.Cm28 | GLU 218 | 5.42x43 | VdWContact |
| GLU 2 | NTc.Cm28 | LEU 274 | 6.55x55 | Hydrophobic |
| GLU 2 | NTc.Cm28 | LYS 298 | 7.35x34 | Anionic |
| GLU 2 | NTc.Cm28 | LYS 298 | 7.35x34 | HBAcceptor |
| GLU 2 | NTc.Cm28 | LYS 298 | 7.35x34 | VdWContact |
| ALA 3 | NTc.Cm27 | TYR 125 | 3.32x32 | Hydrophobic |
| ALA 3 | NTc.Cm27 | TYR 125 | 3.32x32 | VdWContact |
| ALA 3 | NTc.Cm27 | HIS 270 | 6.51x51 | Hydrophobic |
| ALA 3 | NTc.Cm27 | HIS 270 | 6.51x51 | VdWContact |
| ALA 3 | NTc.Cm27 | LEU 274 | 6.55x55 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TRP 102 | 2.60x60 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TRP 102 | 2.60x60 | VdWContact |
| ILE 4 | NTc.Cm26 | LYS 122 | 3.29x29 | HBAcceptor |
| ILE 4 | NTc.Cm26 | LYS 122 | 3.29x29 | Hydrophobic |
| ILE 4 | NTc.Cm26 | LYS 122 | 3.29x29 | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 125 | 3.32x32 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TYR 125 | 3.32x32 | VdWContact |
| ILE 4 | NTc.Cm26 | GLU 302 | 7.39x38 | VdWContact |
| LEU 5 | NTc.Cm25 | VAL 49 | 1.35x35 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 53 | 1.39x39 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 53 | 1.39x39 | VdWContact |
| LEU 5 | NTc.Cm25 | HIS 106 | 2.64x64 | Hydrophobic |
| LEU 5 | NTc.Cm25 | HIS 106 | 2.64x64 | VdWContact |
| LEU 5 | NTc.Cm25 | THR 299 | 7.36x35 | Hydrophobic |
| LEU 5 | NTc.Cm25 | THR 299 | 7.36x35 | VdWContact |
| LEU 5 | NTc.Cm25 | GLU 302 | 7.39x38 | HBDonor |
| LEU 5 | NTc.Cm25 | GLU 302 | 7.39x38 | Hydrophobic |
| LEU 5 | NTc.Cm25 | GLU 302 | 7.39x38 | VdWContact |
| PRO 6 | NTc.Cm24 | GLU 198 | 45.51x51 | Hydrophobic |
| PRO 6 | NTc.Cm24 | GLU 198 | 45.51x51 | VdWContact |
| PRO 6 | NTc.Cm24 | LYS 298 | 7.35x34 | VdWContact |
| ILE 7 | NTc.Cm23 | GLY 109 | 2.67x67 | VdWContact |
| ALA 8 | NTc.Cm22 | LEU 38 | - | Hydrophobic |
| ALA 8 | NTc.Cm22 | VAL 41 | 1.27x27 | Hydrophobic |
| ALA 8 | NTc.Cm22 | ARG 42 | 1.28x28 | Hydrophobic |
| ALA 8 | NTc.Cm22 | ARG 42 | 1.28x28 | VdWContact |
| SER 9 | NTc.Cm21 | LEU 38 | - | VdWContact |
| SER 10 | NTc.Cm20 | LEU 35 | - | VdWContact |
| SER 10 | NTc.Cm20 | CYS 36 | - | VdWContact |
| SER 10 | NTc.Cm20 | SER 37 | - | VdWContact |
| SER 10 | NTc.Cm20 | LEU 38 | - | HBAcceptor |
| SER 10 | NTc.Cm20 | LEU 38 | - | VdWContact |
| SER 10 | NTc.Cm20 | GLN 192 | - | HBAcceptor |
| SER 10 | NTc.Cm20 | GLN 192 | - | VdWContact |
| CYS 11 | NTc.Cm19 | CYS 36 | - | HBAcceptor |
| CYS 11 | NTc.Cm19 | CYS 36 | - | VdWContact |
| CYS 12 | NTc.Cm18 | LEU 35 | - | Hydrophobic |
| THR 13 | NTc.Cm17 | CYS 36 | - | Hydrophobic |
| THR 13 | NTc.Cm17 | MET 284 | 6.65x65 | VdWContact |
| THR 13 | NTc.Cm17 | ARG 286 | - | HBDonor |
| THR 13 | NTc.Cm17 | ARG 286 | - | VdWContact |
| THR 13 | NTc.Cm17 | GLU 291 | 7.28x27 | Hydrophobic |
| THR 13 | NTc.Cm17 | GLU 291 | 7.28x27 | VdWContact |
| GLU 14 | NTc.Cm16 | GLU 32 | - | VdWContact |
| GLU 14 | NTc.Cm16 | MET 284 | 6.65x65 | VdWContact |
| GLU 14 | NTc.Cm16 | ASN 285 | - | VdWContact |
| VAL 15 | NTc.Cm15 | MET 284 | 6.65x65 | Hydrophobic |
| VAL 15 | NTc.Cm15 | MET 284 | 6.65x65 | VdWContact |
| SER 16 | NTc.Cm14 | MET 33 | - | VdWContact |
| HIS 17 | NTc.Cm13 | MET 284 | 6.65x65 | Hydrophobic |
| SER 20 | NTc.Cm10 | TYR 27 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 27 | - | Hydrophobic |
| ARG 22 | NTc.Cm8 | TYR 27 | - | VdWContact |
| LEU 23 | NTc.Cm7 | TYR 27 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | VAL 29 | - | Hydrophobic |
| ARG 31 | CX.5 | GLN 192 | - | VdWContact |
| ALA 35 | cxb1.6 | PRO 207 | 5.31x32 | Hydrophobic |
| ALA 35 | cxb1.6 | ILE 208 | 5.32x33 | Hydrophobic |
| ALA 35 | cxb1.6 | LYS 211 | 5.35x36 | HBAcceptor |
| ALA 35 | cxb1.6 | LYS 211 | 5.35x36 | VdWContact |
| ASP 36 | cxb1.7 | LYS 200 | - | VdWContact |
| ASP 36 | cxb1.7 | TYR 201 | - | HBAcceptor |
| ASP 36 | cxb1.7 | TYR 201 | - | VdWContact |
| ASP 36 | cxb1.7 | GLN 202 | - | Hydrophobic |
| ASP 36 | cxb1.7 | GLN 202 | - | VdWContact |
| ASP 36 | cxb1.7 | PRO 207 | 5.31x32 | Hydrophobic |
| GLY 37 | cxb1.8 | LYS 211 | 5.35x36 | HBAcceptor |
| GLY 37 | cxb1.8 | LYS 211 | 5.35x36 | VdWContact |
| ASP 38 | cxb1.10 | TYR 189 | - | HBAcceptor |
| ASP 38 | cxb1.10 | TYR 189 | - | HBDonor |
| ASP 38 | cxb1.10 | TYR 189 | - | VdWContact |
| ASP 38 | cxb1.10 | THR 191 | - | HBAcceptor |
| ASP 38 | cxb1.10 | THR 191 | - | VdWContact |
| CYS 39 | cxb1.11 | LYS 211 | 5.35x36 | VdWContact |
| ASP 40 | cxb1.12 | LYS 211 | 5.35x36 | Anionic |
| ASP 40 | cxb1.12 | LYS 211 | 5.35x36 | HBAcceptor |
| ASP 40 | cxb1.12 | LYS 211 | 5.35x36 | VdWContact |
| ASP 40 | cxb1.12 | LEU 281 | 6.62x62 | Hydrophobic |
| ASP 40 | cxb1.12 | LEU 281 | 6.62x62 | VdWContact |
| ASP 40 | cxb1.12 | GLY 282 | 6.63x63 | VdWContact |
| ASP 40 | cxb1.12 | ARG 286 | - | Anionic |
| ASP 40 | cxb1.12 | ARG 286 | - | HBAcceptor |
| ASP 40 | cxb1.12 | ARG 286 | - | VdWContact |
| LEU 41 | cxb1.13 | MET 284 | 6.65x65 | Hydrophobic |
| ILE 45 | B1.1 | LEU 35 | - | Hydrophobic |
| ARG 51 | B1.7 | VAL 22 | - | VdWContact |
| ARG 51 | B1.7 | LEU 34 | - | Hydrophobic |
| ARG 52 | b1b2.4 | GLU 16 | - | Cationic |
| ARG 52 | b1b2.4 | GLU 16 | - | HBDonor |
| ARG 52 | b1b2.4 | GLU 16 | - | VdWContact |
| ARG 52 | b1b2.4 | LEU 35 | - | HBAcceptor |
| ARG 52 | b1b2.4 | LEU 35 | - | Hydrophobic |
| ARG 52 | b1b2.4 | LEU 35 | - | VdWContact |
| ILE 53 | b1b2.6 | VAL 29 | - | Hydrophobic |
| ILE 53 | b1b2.6 | LEU 34 | - | Hydrophobic |
| CYS 54 | b1b2.7 | MET 33 | - | HBDonor |
| CYS 54 | b1b2.7 | MET 33 | - | VdWContact |
| CYS 54 | b1b2.7 | LEU 35 | - | VdWContact |
