Predicted complex interactions
CCL8_HUMAN + CCR6
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 76
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | LYS 122 | 3.29x29 | Hydrophobic |
| GLN 1 | NTc.Cm33 | THR 182 | 4.60x61 | VdWContact |
| GLN 1 | NTc.Cm33 | ASN 186 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm33 | LEU 274 | 6.55x55 | VdWContact |
| PRO 2 | NTc.Cm32 | LYS 122 | 3.29x29 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 125 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm32 | GLU 302 | 7.39x38 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 302 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | PHE 306 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm32 | PHE 306 | 7.43x42 | VdWContact |
| ASP 3 | NTc.Cm31 | GLU 198 | 45.51x51 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 211 | 5.35x36 | Anionic |
| ASP 3 | NTc.Cm31 | LYS 211 | 5.35x36 | HBAcceptor |
| ASP 3 | NTc.Cm31 | LYS 211 | 5.35x36 | VdWContact |
| ASP 3 | NTc.Cm31 | LYS 298 | 7.35x34 | Anionic |
| ASP 3 | NTc.Cm31 | LYS 298 | 7.35x34 | HBAcceptor |
| ASP 3 | NTc.Cm31 | LYS 298 | 7.35x34 | VdWContact |
| SER 4 | NTc.Cm30 | GLU 198 | 45.51x51 | HBDonor |
| SER 4 | NTc.Cm30 | GLU 198 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm29 | VAL 41 | 1.27x27 | Hydrophobic |
| VAL 5 | NTc.Cm29 | LYS 298 | 7.35x34 | Hydrophobic |
| VAL 5 | NTc.Cm29 | LYS 298 | 7.35x34 | VdWContact |
| ILE 7 | NTc.Cm27 | THR 191 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | VAL 196 | - | Hydrophobic |
| ILE 7 | NTc.Cm27 | VAL 196 | - | VdWContact |
| ILE 7 | NTc.Cm27 | GLU 198 | 45.51x51 | Hydrophobic |
| ILE 7 | NTc.Cm27 | GLU 198 | 45.51x51 | VdWContact |
| PRO 8 | NTc.Cm26 | ARG 42 | 1.28x28 | VdWContact |
| PRO 8 | NTc.Cm26 | GLN 192 | - | VdWContact |
| ILE 9 | NTc.Cm25 | THR 191 | - | Hydrophobic |
| ILE 9 | NTc.Cm25 | GLN 192 | - | VdWContact |
| THR 10 | NTc.Cm24 | LEU 35 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 35 | - | VdWContact |
| THR 10 | NTc.Cm24 | GLN 192 | - | HBAcceptor |
| THR 10 | NTc.Cm24 | GLN 192 | - | HBDonor |
| THR 10 | NTc.Cm24 | GLN 192 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 36 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | MET 284 | 6.65x65 | VdWContact |
| PHE 13 | NTc.Cm21 | ASN 285 | - | HBAcceptor |
| PHE 13 | NTc.Cm21 | ASN 285 | - | VdWContact |
| PHE 13 | NTc.Cm21 | ARG 286 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | ARG 286 | - | VdWContact |
| PHE 13 | NTc.Cm21 | GLU 291 | 7.28x27 | Hydrophobic |
| PHE 13 | NTc.Cm21 | GLU 291 | 7.28x27 | VdWContact |
| ASN 14 | NTc.Cm20 | GLU 32 | - | HBDonor |
| ASN 14 | NTc.Cm20 | GLU 32 | - | VdWContact |
| ASN 14 | NTc.Cm20 | ASN 285 | - | VdWContact |
| VAL 15 | NTc.Cm19 | MET 284 | 6.65x65 | Hydrophobic |
| ILE 16 | NTc.Cm18 | VAL 29 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | MET 33 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | MET 33 | - | VdWContact |
| ASN 17 | NTc.Cm17 | MET 33 | - | Hydrophobic |
| ASN 17 | NTc.Cm17 | MET 33 | - | VdWContact |
| ARG 18 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| ARG 18 | NTc.Cm16 | TYR 27 | - | VdWContact |
| ASN 33 | NTc.Cm1 | THR 191 | - | VdWContact |
| ILE 34 | CX.1 | GLN 202 | - | Hydrophobic |
| ILE 34 | CX.1 | PRO 207 | 5.31x32 | Hydrophobic |
| GLN 35 | CX.5 | LYS 211 | 5.35x36 | HBAcceptor |
| GLN 35 | CX.5 | LYS 211 | 5.35x36 | VdWContact |
| PRO 37 | cxb1.2 | GLY 282 | 6.63x63 | VdWContact |
| PRO 37 | cxb1.2 | LYS 283 | 6.64x64 | VdWContact |
| PRO 37 | cxb1.2 | MET 284 | 6.65x65 | Hydrophobic |
| PRO 37 | cxb1.2 | ARG 286 | - | VdWContact |
| LYS 38 | cxb1.5 | MET 284 | 6.65x65 | Hydrophobic |
| LYS 38 | cxb1.5 | MET 284 | 6.65x65 | VdWContact |
| ILE 42 | cxb1.10 | LEU 35 | - | Hydrophobic |
| LYS 49 | B1.3 | LEU 34 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 35 | - | HBAcceptor |
| GLU 50 | B1.4 | LEU 35 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 35 | - | VdWContact |
| VAL 51 | B1.5 | VAL 29 | - | Hydrophobic |
| VAL 51 | B1.5 | VAL 29 | - | VdWContact |
| VAL 51 | B1.5 | LEU 34 | - | Hydrophobic |
| CYS 52 | B1.6 | MET 33 | - | HBDonor |
| CYS 52 | B1.6 | MET 33 | - | VdWContact |
