Predicted complex interactions
CXCL10_HUMAN + CCR6
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 109
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | ARG 42 | 1.28x28 | VdWContact |
| PRO 2 | NTc.Cm28 | ARG 42 | 1.28x28 | VdWContact |
| LEU 3 | NTc.Cm27 | GLN 192 | - | VdWContact |
| SER 4 | NTc.Cm26 | ARG 42 | 1.28x28 | VdWContact |
| ARG 5 | NTc.Cm25 | SER 45 | 1.31x31 | VdWContact |
| ARG 5 | NTc.Cm25 | SER 105 | 2.63x63 | HBDonor |
| ARG 5 | NTc.Cm25 | SER 105 | 2.63x63 | VdWContact |
| ARG 5 | NTc.Cm25 | HIS 106 | 2.64x64 | CationPi |
| ARG 5 | NTc.Cm25 | HIS 106 | 2.64x64 | HBDonor |
| ARG 5 | NTc.Cm25 | HIS 106 | 2.64x64 | VdWContact |
| ARG 5 | NTc.Cm25 | GLY 109 | 2.67x67 | VdWContact |
| THR 6 | NTc.Cm24 | LEU 38 | - | VdWContact |
| THR 6 | NTc.Cm24 | LYS 298 | 7.35x34 | Hydrophobic |
| VAL 7 | NTc.Cm23 | THR 191 | - | Hydrophobic |
| ARG 8 | NTc.Cm22 | THR 277 | 6.58x58 | HBDonor |
| ARG 8 | NTc.Cm22 | THR 277 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | LEU 281 | 6.62x62 | Hydrophobic |
| ARG 8 | NTc.Cm22 | GLU 291 | 7.28x27 | Cationic |
| ARG 8 | NTc.Cm22 | GLU 291 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm22 | GLU 291 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm22 | ILE 294 | 7.31x30 | VdWContact |
| CYS 9 | NTc.Cm21 | GLY 282 | 6.63x63 | VdWContact |
| CYS 9 | NTc.Cm21 | ARG 286 | - | HBAcceptor |
| CYS 9 | NTc.Cm21 | ARG 286 | - | VdWContact |
| THR 10 | NTc.Cm20 | CYS 36 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 36 | - | VdWContact |
| CYS 11 | NTc.Cm19 | LEU 34 | - | VdWContact |
| CYS 11 | NTc.Cm19 | ARG 286 | - | HBAcceptor |
| CYS 11 | NTc.Cm19 | ARG 286 | - | VdWContact |
| ILE 12 | NTc.Cm18 | LEU 34 | - | HBDonor |
| ILE 12 | NTc.Cm18 | LEU 34 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 36 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ASN 285 | - | VdWContact |
| ILE 12 | NTc.Cm18 | ARG 286 | - | HBAcceptor |
| ILE 12 | NTc.Cm18 | ARG 286 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | ARG 286 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 288 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 288 | 7.25x24 | VdWContact |
| ILE 12 | NTc.Cm18 | GLU 291 | 7.28x27 | Hydrophobic |
| SER 13 | NTc.Cm17 | MET 33 | - | HBDonor |
| SER 13 | NTc.Cm17 | MET 33 | - | VdWContact |
| SER 13 | NTc.Cm17 | LEU 34 | - | VdWContact |
| ILE 14 | NTc.Cm16 | MET 284 | 6.65x65 | Hydrophobic |
| GLN 17 | NTc.Cm13 | TYR 27 | - | VdWContact |
| PRO 18 | NTc.Cm12 | VAL 22 | - | Hydrophobic |
| ASN 20 | NTc.Cm10 | THR 24 | - | Hydrophobic |
| ASN 20 | NTc.Cm10 | TYR 26 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 12 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 12 | - | VdWContact |
| PRO 21 | NTc.Cm9 | PHE 19 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | PHE 19 | - | VdWContact |
| ARG 22 | NTc.Cm8 | GLU 16 | - | Cationic |
| ARG 22 | NTc.Cm8 | GLU 16 | - | HBDonor |
| ARG 22 | NTc.Cm8 | GLU 16 | - | VdWContact |
| SER 23 | NTc.Cm7 | TYR 26 | - | VdWContact |
| LEU 24 | NTc.Cm6 | PHE 8 | - | Hydrophobic |
| GLU 25 | NTc.Cm5 | PHE 8 | - | HBAcceptor |
| GLU 25 | NTc.Cm5 | PHE 8 | - | VdWContact |
| LYS 26 | NTc.Cm4 | SER 5 | - | VdWContact |
| LEU 27 | NTc.Cm3 | PHE 8 | - | Hydrophobic |
| LEU 27 | NTc.Cm3 | PHE 8 | - | VdWContact |
| GLN 34 | cxb1.2 | TYR 189 | - | HBDonor |
| GLN 34 | cxb1.2 | TYR 189 | - | VdWContact |
| GLN 34 | cxb1.2 | LYS 200 | - | VdWContact |
| GLN 34 | cxb1.2 | PRO 207 | 5.31x32 | Hydrophobic |
| PHE 35 | cxb1.5 | TYR 189 | - | Hydrophobic |
| PHE 35 | cxb1.5 | TYR 189 | - | VdWContact |
| PHE 35 | cxb1.5 | THR 191 | - | Hydrophobic |
| PHE 35 | cxb1.5 | THR 191 | - | VdWContact |
| PHE 35 | cxb1.5 | VAL 196 | - | Hydrophobic |
| PHE 35 | cxb1.5 | GLU 198 | 45.51x51 | Hydrophobic |
| PHE 35 | cxb1.5 | GLU 198 | 45.51x51 | VdWContact |
| PHE 35 | cxb1.5 | LEU 281 | 6.62x62 | VdWContact |
| PRO 37 | cxb1.7 | ILE 208 | 5.32x33 | Hydrophobic |
| PRO 37 | cxb1.7 | ILE 208 | 5.32x33 | VdWContact |
| PRO 37 | cxb1.7 | GLY 282 | 6.63x63 | VdWContact |
| ARG 38 | cxb1.8 | GLY 282 | 6.63x63 | VdWContact |
| ARG 38 | cxb1.8 | LYS 283 | 6.64x64 | HBDonor |
| ARG 38 | cxb1.8 | LYS 283 | 6.64x64 | VdWContact |
| ILE 42 | cxb1.15 | LEU 35 | - | Hydrophobic |
| MET 45 | B1.2 | TYR 26 | - | Hydrophobic |
| GLU 50 | B1.7 | SER 31 | - | VdWContact |
| LYS 51 | b1b2.4 | SER 31 | - | HBDonor |
| LYS 51 | b1b2.4 | SER 31 | - | VdWContact |
| LYS 51 | b1b2.4 | LEU 35 | - | Hydrophobic |
| LYS 51 | b1b2.4 | LEU 35 | - | VdWContact |
| ARG 52 | b1b2.6 | LEU 34 | - | Hydrophobic |
| CYS 53 | b1b2.7 | LEU 34 | - | Hydrophobic |
| CYS 53 | b1b2.7 | LEU 34 | - | VdWContact |
| CYS 53 | b1b2.7 | LEU 35 | - | VdWContact |
| LEU 64 | B2.4 | PHE 8 | - | Hydrophobic |
| LEU 64 | B2.4 | PHE 12 | - | Hydrophobic |
| LEU 64 | B2.4 | PHE 19 | - | Hydrophobic |
| ALA 67 | b2b3.2 | PHE 12 | - | Hydrophobic |
| VAL 68 | b2b3.3 | MET 6 | - | Hydrophobic |
| VAL 68 | b2b3.3 | MET 6 | - | VdWContact |
| VAL 68 | b2b3.3 | PHE 8 | - | Hydrophobic |
| VAL 68 | b2b3.3 | PHE 8 | - | VdWContact |
| VAL 68 | b2b3.3 | PHE 12 | - | Hydrophobic |
| VAL 68 | b2b3.3 | PHE 12 | - | VdWContact |
| GLU 71 | b2b3.12 | VAL 11 | - | Hydrophobic |
| GLU 71 | b2b3.12 | VAL 11 | - | VdWContact |
| ARG 72 | B3.1 | GLU 4 | - | Cationic |
| ARG 72 | B3.1 | GLU 4 | - | HBDonor |
| ARG 72 | B3.1 | GLU 4 | - | VdWContact |
| ARG 72 | B3.1 | MET 6 | - | Hydrophobic |
| ARG 72 | B3.1 | MET 6 | - | VdWContact |
| ARG 75 | B3.4 | ASP 10 | - | Cationic |
| ARG 75 | B3.4 | ASP 10 | - | VdWContact |
