Predicted complex interactions
CXCL13_HUMAN + CCR6
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 128
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | TYR 125 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 125 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm32 | PHE 129 | 3.36x36 | Hydrophobic |
| VAL 1 | NTc.Cm32 | GLU 218 | 5.42x43 | Cationic |
| VAL 1 | NTc.Cm32 | GLU 218 | 5.42x43 | HBDonor |
| VAL 1 | NTc.Cm32 | GLU 218 | 5.42x43 | VdWContact |
| VAL 1 | NTc.Cm32 | HIS 270 | 6.51x51 | Hydrophobic |
| VAL 1 | NTc.Cm32 | LEU 274 | 6.55x55 | Hydrophobic |
| LEU 2 | NTc.Cm31 | LYS 122 | 3.29x29 | HBAcceptor |
| LEU 2 | NTc.Cm31 | LYS 122 | 3.29x29 | VdWContact |
| LEU 2 | NTc.Cm31 | HIS 270 | 6.51x51 | Hydrophobic |
| LEU 2 | NTc.Cm31 | HIS 270 | 6.51x51 | VdWContact |
| LEU 2 | NTc.Cm31 | LEU 274 | 6.55x55 | Hydrophobic |
| LEU 2 | NTc.Cm31 | LEU 274 | 6.55x55 | VdWContact |
| LEU 2 | NTc.Cm31 | LYS 298 | 7.35x34 | Hydrophobic |
| GLU 3 | NTc.Cm30 | LYS 211 | 5.35x36 | Anionic |
| GLU 3 | NTc.Cm30 | LYS 211 | 5.35x36 | HBAcceptor |
| GLU 3 | NTc.Cm30 | LYS 211 | 5.35x36 | VdWContact |
| GLU 3 | NTc.Cm30 | LEU 274 | 6.55x55 | Hydrophobic |
| GLU 3 | NTc.Cm30 | LEU 274 | 6.55x55 | VdWContact |
| GLU 3 | NTc.Cm30 | LYS 298 | 7.35x34 | HBAcceptor |
| GLU 3 | NTc.Cm30 | LYS 298 | 7.35x34 | VdWContact |
| VAL 4 | NTc.Cm29 | HIS 270 | 6.51x51 | Hydrophobic |
| VAL 4 | NTc.Cm29 | HIS 270 | 6.51x51 | VdWContact |
| VAL 4 | NTc.Cm29 | LYS 298 | 7.35x34 | HBAcceptor |
| VAL 4 | NTc.Cm29 | LYS 298 | 7.35x34 | VdWContact |
| VAL 4 | NTc.Cm29 | GLU 302 | 7.39x38 | Hydrophobic |
| VAL 4 | NTc.Cm29 | GLU 302 | 7.39x38 | VdWContact |
| TYR 5 | NTc.Cm28 | TRP 102 | 2.60x60 | HBDonor |
| TYR 5 | NTc.Cm28 | TRP 102 | 2.60x60 | Hydrophobic |
| TYR 5 | NTc.Cm28 | TRP 102 | 2.60x60 | VdWContact |
| TYR 5 | NTc.Cm28 | SER 105 | 2.63x63 | VdWContact |
| TYR 5 | NTc.Cm28 | HIS 106 | 2.64x64 | Hydrophobic |
| TYR 5 | NTc.Cm28 | HIS 106 | 2.64x64 | PiStacking |
| TYR 5 | NTc.Cm28 | HIS 106 | 2.64x64 | VdWContact |
| TYR 6 | NTc.Cm27 | SER 105 | 2.63x63 | VdWContact |
| TYR 6 | NTc.Cm27 | GLY 109 | 2.67x67 | VdWContact |
| TYR 6 | NTc.Cm27 | ALA 110 | 23.49x49 | VdWContact |
| TYR 6 | NTc.Cm27 | TRP 111 | 23.50x50 | Hydrophobic |
| TYR 6 | NTc.Cm27 | TRP 111 | 23.50x50 | VdWContact |
| TYR 6 | NTc.Cm27 | VAL 196 | - | Hydrophobic |
| TYR 6 | NTc.Cm27 | VAL 196 | - | VdWContact |
| TYR 6 | NTc.Cm27 | GLU 198 | 45.51x51 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 298 | 7.35x34 | Hydrophobic |
| THR 7 | NTc.Cm26 | LYS 298 | 7.35x34 | VdWContact |
| LEU 9 | NTc.Cm24 | THR 191 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | THR 191 | - | VdWContact |
| LEU 9 | NTc.Cm24 | GLN 192 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | VAL 196 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | VAL 196 | - | VdWContact |
| ARG 10 | NTc.Cm23 | THR 277 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | GLU 291 | 7.28x27 | Cationic |
| ARG 10 | NTc.Cm23 | GLU 291 | 7.28x27 | HBDonor |
| ARG 10 | NTc.Cm23 | GLU 291 | 7.28x27 | VdWContact |
| ARG 10 | NTc.Cm23 | ILE 294 | 7.31x30 | VdWContact |
| CYS 11 | NTc.Cm22 | ARG 286 | - | VdWContact |
| ARG 12 | NTc.Cm21 | LEU 35 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | CYS 36 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 36 | - | VdWContact |
| ARG 12 | NTc.Cm21 | GLN 192 | - | HBDonor |
| ARG 12 | NTc.Cm21 | GLN 192 | - | VdWContact |
| VAL 14 | NTc.Cm19 | LEU 34 | - | HBDonor |
| VAL 14 | NTc.Cm19 | LEU 34 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 36 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | ARG 286 | - | HBAcceptor |
| VAL 14 | NTc.Cm19 | ARG 286 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | ARG 286 | - | VdWContact |
| VAL 14 | NTc.Cm19 | GLU 291 | 7.28x27 | Hydrophobic |
| GLN 15 | NTc.Cm18 | GLU 32 | - | HBDonor |
| GLN 15 | NTc.Cm18 | GLU 32 | - | VdWContact |
| GLN 15 | NTc.Cm18 | LEU 34 | - | Hydrophobic |
| GLN 15 | NTc.Cm18 | LEU 34 | - | VdWContact |
| GLN 15 | NTc.Cm18 | MET 284 | 6.65x65 | VdWContact |
| GLU 16 | NTc.Cm17 | MET 284 | 6.65x65 | Hydrophobic |
| GLU 16 | NTc.Cm17 | MET 284 | 6.65x65 | VdWContact |
| VAL 19 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| VAL 19 | NTc.Cm14 | TYR 27 | - | VdWContact |
| PHE 20 | NTc.Cm13 | PHE 19 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | PHE 19 | - | VdWContact |
| PHE 20 | NTc.Cm13 | TYR 27 | - | Hydrophobic |
| PHE 20 | NTc.Cm13 | TYR 27 | - | VdWContact |
| PRO 22 | NTc.Cm11 | TYR 27 | - | Hydrophobic |
| PRO 22 | NTc.Cm11 | TYR 27 | - | VdWContact |
| ARG 23 | NTc.Cm10 | PHE 8 | - | VdWContact |
| ARG 23 | NTc.Cm10 | PHE 12 | - | CationPi |
| ARG 23 | NTc.Cm10 | PHE 12 | - | VdWContact |
| ARG 24 | NTc.Cm9 | THR 24 | - | VdWContact |
| ARG 28 | NTc.Cm5 | SER 5 | - | VdWContact |
| ILE 29 | NTc.Cm4 | PHE 8 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | PHE 8 | - | VdWContact |
| LEU 32 | NTc.Cm1 | GLN 192 | - | Hydrophobic |
| ASN 36 | cxb1.1 | TYR 189 | - | Hydrophobic |
| ASN 36 | cxb1.1 | LYS 200 | - | VdWContact |
| ASN 36 | cxb1.1 | TYR 201 | - | VdWContact |
| ASN 36 | cxb1.1 | LYS 211 | 5.35x36 | HBAcceptor |
| ASN 36 | cxb1.1 | LYS 211 | 5.35x36 | VdWContact |
| GLY 37 | cxb1.2 | LEU 281 | 6.62x62 | VdWContact |
| PRO 39 | cxb1.6 | ILE 208 | 5.32x33 | Hydrophobic |
| PRO 39 | cxb1.6 | ILE 208 | 5.32x33 | VdWContact |
| PRO 39 | cxb1.6 | LEU 281 | 6.62x62 | Hydrophobic |
| ARG 40 | cxb1.7 | MET 284 | 6.65x65 | VdWContact |
| ARG 40 | cxb1.7 | ARG 286 | - | VdWContact |
| ILE 44 | cxb1.14 | LEU 35 | - | Hydrophobic |
| ILE 44 | cxb1.14 | LEU 35 | - | VdWContact |
| LYS 47 | B1.1 | VAL 29 | - | VdWContact |
| ILE 52 | B1.6 | LEU 35 | - | Hydrophobic |
| VAL 53 | B1.7 | VAL 29 | - | Hydrophobic |
| VAL 53 | B1.7 | LEU 34 | - | Hydrophobic |
| VAL 53 | B1.7 | LEU 34 | - | VdWContact |
| CYS 54 | b1b2.4 | LEU 34 | - | Hydrophobic |
| CYS 54 | b1b2.4 | LEU 34 | - | VdWContact |
| MET 65 | B2.2 | PHE 8 | - | Hydrophobic |
| MET 65 | B2.2 | PHE 19 | - | Hydrophobic |
| VAL 68 | B2.5 | PHE 12 | - | Hydrophobic |
| VAL 68 | B2.5 | PHE 12 | - | VdWContact |
| LEU 69 | B2.6 | MET 6 | - | Hydrophobic |
| LEU 69 | B2.6 | PHE 8 | - | Hydrophobic |
| LEU 69 | B2.6 | PHE 8 | - | VdWContact |
| LEU 69 | B2.6 | PHE 12 | - | Hydrophobic |
| LEU 69 | B2.6 | PHE 12 | - | VdWContact |
| ARG 72 | b2b3.11 | VAL 11 | - | HBDonor |
| ARG 72 | b2b3.11 | VAL 11 | - | Hydrophobic |
| ARG 72 | b2b3.11 | VAL 11 | - | VdWContact |
| ARG 72 | b2b3.11 | PHE 12 | - | VdWContact |
| ARG 72 | b2b3.11 | SER 14 | - | HBDonor |
| ARG 72 | b2b3.11 | SER 14 | - | VdWContact |
| ARG 72 | b2b3.11 | SER 15 | - | HBDonor |
| ARG 72 | b2b3.11 | SER 15 | - | VdWContact |
