Predicted complex interactions
CXCL8_HUMAN + CCR6
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR6 View partner entry
- Partner description
- UniProt: P51684; Gene: ccr6_human; Family: Chemokine
- Interactions detected
- 125
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 1 | NTc.Cm33 | SER 5 | - | HBDonor |
| GLU 1 | NTc.Cm33 | SER 5 | - | VdWContact |
| GLY 2 | NTc.Cm32 | GLY 3 | - | HBDonor |
| GLY 2 | NTc.Cm32 | GLY 3 | - | VdWContact |
| GLY 2 | NTc.Cm32 | SER 5 | - | VdWContact |
| ARG 7 | NTc.Cm27 | GLY 193 | - | VdWContact |
| ALA 9 | NTc.Cm25 | ARG 42 | 1.28x28 | HBAcceptor |
| ALA 9 | NTc.Cm25 | ARG 42 | 1.28x28 | VdWContact |
| LYS 10 | NTc.Cm24 | ASN 190 | - | VdWContact |
| LYS 10 | NTc.Cm24 | THR 191 | - | HBDonor |
| LYS 10 | NTc.Cm24 | THR 191 | - | VdWContact |
| LYS 10 | NTc.Cm24 | GLN 192 | - | VdWContact |
| LYS 10 | NTc.Cm24 | GLY 193 | - | HBDonor |
| LYS 10 | NTc.Cm24 | GLY 193 | - | VdWContact |
| LYS 10 | NTc.Cm24 | SER 194 | - | HBDonor |
| LYS 10 | NTc.Cm24 | SER 194 | - | VdWContact |
| LYS 10 | NTc.Cm24 | VAL 196 | - | Hydrophobic |
| GLU 11 | NTc.Cm23 | LEU 38 | - | HBAcceptor |
| GLU 11 | NTc.Cm23 | LEU 38 | - | VdWContact |
| GLU 11 | NTc.Cm23 | ARG 42 | 1.28x28 | Anionic |
| GLU 11 | NTc.Cm23 | ARG 42 | 1.28x28 | HBAcceptor |
| GLU 11 | NTc.Cm23 | ARG 42 | 1.28x28 | VdWContact |
| LEU 12 | NTc.Cm22 | VAL 196 | - | Hydrophobic |
| LEU 12 | NTc.Cm22 | GLU 198 | 45.51x51 | Hydrophobic |
| ARG 13 | NTc.Cm21 | CYS 36 | - | Cationic |
| ARG 13 | NTc.Cm21 | CYS 36 | - | HBDonor |
| ARG 13 | NTc.Cm21 | CYS 36 | - | VdWContact |
| ARG 13 | NTc.Cm21 | GLU 291 | 7.28x27 | Cationic |
| ARG 13 | NTc.Cm21 | GLU 291 | 7.28x27 | HBDonor |
| ARG 13 | NTc.Cm21 | GLU 291 | 7.28x27 | VdWContact |
| CYS 14 | NTc.Cm20 | GLY 282 | 6.63x63 | VdWContact |
| CYS 14 | NTc.Cm20 | ARG 286 | - | HBAcceptor |
| CYS 14 | NTc.Cm20 | ARG 286 | - | VdWContact |
| GLN 15 | NTc.Cm19 | LEU 35 | - | Hydrophobic |
| GLN 15 | NTc.Cm19 | GLN 192 | - | VdWContact |
| CYS 16 | NTc.Cm18 | ARG 286 | - | HBAcceptor |
| CYS 16 | NTc.Cm18 | ARG 286 | - | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 36 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 36 | - | VdWContact |
| ILE 17 | NTc.Cm17 | ASN 285 | - | HBAcceptor |
| ILE 17 | NTc.Cm17 | ASN 285 | - | VdWContact |
| ILE 17 | NTc.Cm17 | ARG 286 | - | HBAcceptor |
| ILE 17 | NTc.Cm17 | ARG 286 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | ARG 286 | - | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 288 | 7.25x24 | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 288 | 7.25x24 | VdWContact |
| ILE 17 | NTc.Cm17 | GLU 291 | 7.28x27 | Hydrophobic |
| ILE 17 | NTc.Cm17 | GLU 291 | 7.28x27 | VdWContact |
| LYS 18 | NTc.Cm16 | GLU 32 | - | Cationic |
| LYS 18 | NTc.Cm16 | GLU 32 | - | HBDonor |
| LYS 18 | NTc.Cm16 | GLU 32 | - | VdWContact |
| THR 19 | NTc.Cm15 | MET 284 | 6.65x65 | Hydrophobic |
| THR 19 | NTc.Cm15 | MET 284 | 6.65x65 | VdWContact |
| TYR 20 | NTc.Cm14 | TYR 26 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | VAL 29 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | MET 33 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | MET 33 | - | VdWContact |
| PRO 23 | NTc.Cm11 | VAL 22 | - | Hydrophobic |
| PRO 23 | NTc.Cm11 | VAL 22 | - | VdWContact |
| PHE 24 | NTc.Cm10 | VAL 22 | - | VdWContact |
| PHE 24 | NTc.Cm10 | TYR 26 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 26 | - | VdWContact |
| HIS 25 | NTc.Cm9 | PHE 12 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | PHE 12 | - | VdWContact |
| HIS 25 | NTc.Cm9 | PHE 19 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | PHE 19 | - | VdWContact |
| PRO 26 | NTc.Cm8 | PHE 12 | - | Hydrophobic |
| PRO 26 | NTc.Cm8 | PHE 12 | - | VdWContact |
| PRO 26 | NTc.Cm8 | PHE 19 | - | Hydrophobic |
| PRO 26 | NTc.Cm8 | PHE 19 | - | VdWContact |
| LYS 27 | NTc.Cm7 | PHE 12 | - | Hydrophobic |
| LYS 27 | NTc.Cm7 | PHE 12 | - | VdWContact |
| PHE 28 | NTc.Cm6 | THR 24 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | TYR 26 | - | Hydrophobic |
| ILE 35 | CX.4 | GLN 192 | - | VdWContact |
| PRO 39 | cxb1.5 | LYS 200 | - | Hydrophobic |
| PRO 39 | cxb1.5 | LYS 200 | - | VdWContact |
| PRO 39 | cxb1.5 | LYS 211 | 5.35x36 | HBAcceptor |
| PRO 39 | cxb1.5 | LYS 211 | 5.35x36 | VdWContact |
| HIS 40 | cxb1.6 | TYR 189 | - | Hydrophobic |
| HIS 40 | cxb1.6 | TYR 189 | - | VdWContact |
| HIS 40 | cxb1.6 | THR 191 | - | Hydrophobic |
| HIS 40 | cxb1.6 | GLU 198 | 45.51x51 | Hydrophobic |
| HIS 40 | cxb1.6 | LEU 281 | 6.62x62 | VdWContact |
| ALA 42 | cxb1.8 | ILE 208 | 5.32x33 | Hydrophobic |
| ALA 42 | cxb1.8 | ILE 208 | 5.32x33 | VdWContact |
| ALA 42 | cxb1.8 | GLY 282 | 6.63x63 | VdWContact |
| ASN 43 | cxb1.10 | GLY 282 | 6.63x63 | HBDonor |
| ASN 43 | cxb1.10 | GLY 282 | 6.63x63 | VdWContact |
| ASN 43 | cxb1.10 | MET 284 | 6.65x65 | VdWContact |
| ILE 47 | cxb1.16 | LEU 35 | - | Hydrophobic |
| LEU 50 | B1.3 | TYR 26 | - | Hydrophobic |
| LEU 50 | B1.3 | TYR 26 | - | VdWContact |
| ARG 54 | B1.7 | TYR 26 | - | HBDonor |
| ARG 54 | B1.7 | TYR 26 | - | VdWContact |
| ARG 54 | B1.7 | TYR 27 | - | HBDonor |
| ARG 54 | B1.7 | TYR 27 | - | VdWContact |
| ARG 54 | B1.7 | VAL 29 | - | VdWContact |
| ARG 54 | B1.7 | LEU 34 | - | Hydrophobic |
| ARG 54 | B1.7 | LEU 34 | - | VdWContact |
| GLU 55 | b1b2.4 | LEU 35 | - | HBAcceptor |
| GLU 55 | b1b2.4 | LEU 35 | - | Hydrophobic |
| GLU 55 | b1b2.4 | LEU 35 | - | VdWContact |
| LEU 56 | b1b2.6 | TYR 26 | - | Hydrophobic |
| LEU 56 | b1b2.6 | TYR 26 | - | VdWContact |
| LEU 56 | b1b2.6 | VAL 29 | - | Hydrophobic |
| LEU 56 | b1b2.6 | VAL 29 | - | VdWContact |
| LEU 56 | b1b2.6 | LEU 34 | - | Hydrophobic |
| TRP 64 | b1b2.16 | TYR 18 | - | Hydrophobic |
| TRP 64 | b1b2.16 | PHE 19 | - | Hydrophobic |
| ARG 67 | B2.3 | TYR 18 | - | CationPi |
| VAL 68 | B2.4 | PHE 19 | - | Hydrophobic |
| LYS 71 | b2b3.2 | PHE 12 | - | Hydrophobic |
| LYS 71 | b2b3.2 | SER 15 | - | HBDonor |
| LYS 71 | b2b3.2 | SER 15 | - | VdWContact |
| PHE 72 | b2b3.4 | PHE 8 | - | Hydrophobic |
| PHE 72 | b2b3.4 | PHE 8 | - | VdWContact |
| PHE 72 | b2b3.4 | PHE 12 | - | Hydrophobic |
| ARG 75 | B3.1 | ASN 7 | - | HBDonor |
| ARG 75 | B3.1 | ASN 7 | - | VdWContact |
| ARG 75 | B3.1 | PHE 8 | - | CationPi |
| ARG 75 | B3.1 | PHE 8 | - | HBDonor |
| ARG 75 | B3.1 | PHE 8 | - | Hydrophobic |
| ARG 75 | B3.1 | PHE 8 | - | VdWContact |
| SER 79 | b3h.1 | MET 6 | - | VdWContact |
