Predicted complex interactions
CCL15_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 114
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 17 | NTc.Cm36 | GLU 194 | 4.61x62 | VdWContact |
| GLU 18 | NTc.Cm35 | ILE 269 | 6.41x41 | Hydrophobic |
| GLU 18 | NTc.Cm35 | ILE 269 | 6.41x41 | VdWContact |
| PRO 20 | NTc.Cm33 | VAL 193 | 4.60x61 | Hydrophobic |
| PRO 20 | NTc.Cm33 | VAL 193 | 4.60x61 | VdWContact |
| PRO 20 | NTc.Cm33 | ILE 197 | 4.64x65 | Hydrophobic |
| PRO 20 | NTc.Cm33 | ILE 197 | 4.64x65 | VdWContact |
| PRO 20 | NTc.Cm33 | PHE 267 | 6.39x39 | Hydrophobic |
| VAL 21 | NTc.Cm32 | ASN 266 | 6.38x38 | HBAcceptor |
| VAL 21 | NTc.Cm32 | ASN 266 | 6.38x38 | Hydrophobic |
| VAL 21 | NTc.Cm32 | ASN 266 | 6.38x38 | VdWContact |
| VAL 22 | NTc.Cm31 | THR 190 | 4.57x57 | Hydrophobic |
| VAL 22 | NTc.Cm31 | THR 190 | 4.57x57 | VdWContact |
| VAL 22 | NTc.Cm31 | VAL 193 | 4.60x61 | Hydrophobic |
| VAL 22 | NTc.Cm31 | VAL 193 | 4.60x61 | VdWContact |
| VAL 22 | NTc.Cm31 | PHE 196 | 4.63x64 | Hydrophobic |
| VAL 22 | NTc.Cm31 | PHE 196 | 4.63x64 | VdWContact |
| VAL 22 | NTc.Cm31 | ILE 197 | 4.64x65 | Hydrophobic |
| LEU 23 | NTc.Cm30 | GLN 200 | - | HBAcceptor |
| LEU 23 | NTc.Cm30 | GLN 200 | - | HBDonor |
| LEU 23 | NTc.Cm30 | GLN 200 | - | VdWContact |
| LEU 23 | NTc.Cm30 | MET 204 | - | Hydrophobic |
| LEU 23 | NTc.Cm30 | VAL 259 | 6.31x31 | Hydrophobic |
| LEU 23 | NTc.Cm30 | VAL 259 | 6.31x31 | VdWContact |
| LEU 23 | NTc.Cm30 | GLN 262 | 6.34x34 | Hydrophobic |
| LEU 23 | NTc.Cm30 | THR 263 | 6.35x35 | VdWContact |
| SER 25 | NTc.Cm28 | PHE 109 | 2.55x55 | VdWContact |
| SER 25 | NTc.Cm28 | TYR 284 | 6.56x56 | VdWContact |
| PHE 26 | NTc.Cm27 | TRP 90 | 12.51x51 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 90 | 12.51x51 | PiStacking |
| PHE 26 | NTc.Cm27 | TRP 90 | 12.51x51 | VdWContact |
| PHE 26 | NTc.Cm27 | PHE 109 | 2.55x55 | Hydrophobic |
| PHE 26 | NTc.Cm27 | PHE 109 | 2.55x55 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 112 | 2.58x58 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 288 | 6.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 288 | 6.60x60 | VdWContact |
| HIS 27 | NTc.Cm26 | LYS 33 | - | HBAcceptor |
| HIS 27 | NTc.Cm26 | LYS 33 | - | PiCation |
| HIS 27 | NTc.Cm26 | LYS 33 | - | VdWContact |
| HIS 27 | NTc.Cm26 | ASN 281 | 6.53x53 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ASN 281 | 6.53x53 | VdWContact |
| HIS 27 | NTc.Cm26 | TYR 284 | 6.56x56 | Hydrophobic |
| HIS 27 | NTc.Cm26 | TYR 284 | 6.56x56 | VdWContact |
| HIS 27 | NTc.Cm26 | ASP 285 | 6.57x57 | Hydrophobic |
| HIS 27 | NTc.Cm26 | ASP 285 | 6.57x57 | VdWContact |
| PHE 28 | NTc.Cm25 | TRP 90 | 12.51x51 | Hydrophobic |
| PHE 28 | NTc.Cm25 | ARG 185 | 4.52x52 | Hydrophobic |
| PHE 28 | NTc.Cm25 | ARG 185 | 4.52x52 | VdWContact |
| PHE 28 | NTc.Cm25 | CYS 186 | 4.53x53 | VdWContact |
| ALA 29 | NTc.Cm24 | LYS 26 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | LYS 26 | - | VdWContact |
| ALA 29 | NTc.Cm24 | VAL 29 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | ARG 30 | - | HBAcceptor |
| ALA 29 | NTc.Cm24 | ARG 30 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | ARG 30 | - | VdWContact |
| ALA 29 | NTc.Cm24 | ASN 281 | 6.53x53 | VdWContact |
| ALA 30 | NTc.Cm23 | LYS 26 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LEU 23 | - | Hydrophobic |
| ASP 31 | NTc.Cm22 | CYS 24 | - | VdWContact |
| ASP 31 | NTc.Cm22 | SER 25 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 26 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 26 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ARG 30 | - | Anionic |
| ASP 31 | NTc.Cm22 | ARG 30 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | ARG 30 | - | VdWContact |
| ASP 31 | NTc.Cm22 | SER 180 | 4.47x47 | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 24 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 24 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 24 | - | VdWContact |
| CYS 32 | NTc.Cm21 | LYS 26 | - | Anionic |
| THR 34 | NTc.Cm19 | SER 22 | - | HBDonor |
| THR 34 | NTc.Cm19 | SER 22 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 24 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 274 | 6.46x46 | Hydrophobic |
| SER 35 | NTc.Cm18 | SER 22 | - | VdWContact |
| ILE 37 | NTc.Cm16 | PHE 20 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | PHE 20 | - | VdWContact |
| PRO 42 | NTc.Cm11 | VAL 15 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | VAL 15 | - | VdWContact |
| LEU 45 | NTc.Cm8 | VAL 15 | - | Hydrophobic |
| LEU 45 | NTc.Cm8 | TYR 17 | - | VdWContact |
| PHE 50 | NTc.Cm3 | SER 179 | 4.46x46 | VdWContact |
| GLU 51 | NTc.Cm2 | SER 179 | 4.46x46 | HBAcceptor |
| GLU 51 | NTc.Cm2 | SER 179 | 4.46x46 | VdWContact |
| SER 53 | CX.1 | GLN 176 | 4.43x43 | VdWContact |
| SER 54 | CX.5 | GLN 176 | 4.43x43 | HBAcceptor |
| SER 54 | CX.5 | GLN 176 | 4.43x43 | VdWContact |
| SER 54 | CX.5 | THR 190 | 4.57x57 | VdWContact |
| LYS 58 | cxb1.6 | ILE 269 | 6.41x41 | Hydrophobic |
| LYS 58 | cxb1.6 | ILE 269 | 6.41x41 | VdWContact |
| ILE 62 | cxb1.11 | LEU 23 | - | Hydrophobic |
| ILE 62 | cxb1.11 | LEU 23 | - | VdWContact |
| THR 65 | cxb1.16 | TYR 17 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 17 | - | VdWContact |
| ARG 69 | B1.4 | TYR 17 | - | Hydrophobic |
| ARG 69 | B1.4 | TYR 17 | - | VdWContact |
| GLN 70 | B1.5 | LEU 23 | - | Hydrophobic |
| GLN 70 | B1.5 | LEU 23 | - | VdWContact |
| VAL 71 | B1.6 | TYR 17 | - | Hydrophobic |
| VAL 71 | B1.6 | PHE 20 | - | Hydrophobic |
| VAL 71 | B1.6 | PHE 20 | - | VdWContact |
| CYS 72 | B1.7 | SER 22 | - | VdWContact |
| CYS 72 | B1.7 | LEU 23 | - | VdWContact |
| TYR 90 | b2b3.12 | GLN 182 | 4.49x49 | Hydrophobic |
| TYR 90 | b2b3.12 | GLN 182 | 4.49x49 | VdWContact |
| SER 91 | B3.1 | GLN 182 | 4.49x49 | HBAcceptor |
| SER 91 | B3.1 | GLN 182 | 4.49x49 | VdWContact |
| ILE 92 | B3.2 | ARG 177 | 4.44x44 | Anionic |
| ILE 92 | B3.2 | ARG 177 | 4.44x44 | HBAcceptor |
| ILE 92 | B3.2 | ARG 177 | 4.44x44 | Hydrophobic |
| ILE 92 | B3.2 | ARG 177 | 4.44x44 | VdWContact |
| ILE 92 | B3.2 | SER 179 | 4.46x46 | VdWContact |
| ILE 92 | B3.2 | GLN 182 | 4.49x49 | Hydrophobic |
| ILE 92 | B3.2 | GLN 182 | 4.49x49 | VdWContact |
