Predicted complex interactions
CCL18_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 67
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| THR 5 | NTc.Cm25 | SER 179 | 4.46x46 | VdWContact |
| THR 5 | NTc.Cm25 | SER 180 | 4.47x47 | VdWContact |
| LYS 7 | NTc.Cm23 | ARG 30 | - | VdWContact |
| LYS 7 | NTc.Cm23 | SER 180 | 4.47x47 | VdWContact |
| LYS 7 | NTc.Cm23 | GLU 181 | 4.48x48 | Cationic |
| LYS 7 | NTc.Cm23 | GLU 181 | 4.48x48 | HBDonor |
| LYS 7 | NTc.Cm23 | GLU 181 | 4.48x48 | Hydrophobic |
| LYS 7 | NTc.Cm23 | GLU 181 | 4.48x48 | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 26 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 26 | - | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 27 | - | Anionic |
| GLU 8 | NTc.Cm22 | LYS 27 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 27 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | LYS 27 | - | VdWContact |
| LEU 9 | NTc.Cm21 | LEU 23 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | LEU 23 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 24 | - | VdWContact |
| LEU 9 | NTc.Cm21 | SER 25 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 24 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 24 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 24 | - | Hydrophobic |
| CYS 10 | NTc.Cm20 | CYS 24 | - | VdWContact |
| CYS 10 | NTc.Cm20 | ARG 30 | - | Anionic |
| LEU 12 | NTc.Cm18 | CYS 24 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 24 | - | VdWContact |
| LEU 12 | NTc.Cm18 | ILE 269 | 6.41x41 | VdWContact |
| LEU 12 | NTc.Cm18 | SER 272 | 6.44x44 | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 274 | 6.46x46 | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 274 | 6.46x46 | VdWContact |
| VAL 13 | NTc.Cm17 | GLU 21 | - | Hydrophobic |
| VAL 13 | NTc.Cm17 | GLU 21 | - | VdWContact |
| VAL 13 | NTc.Cm17 | ILE 269 | 6.41x41 | Hydrophobic |
| TYR 14 | NTc.Cm16 | GLU 21 | - | VdWContact |
| THR 15 | NTc.Cm15 | GLU 21 | - | VdWContact |
| TRP 17 | NTc.Cm13 | VAL 4 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | TYR 8 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 8 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 8 | - | VdWContact |
| PHE 23 | NTc.Cm7 | TYR 8 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TYR 8 | - | VdWContact |
| GLU 29 | NTc.Cm1 | SER 179 | 4.46x46 | HBAcceptor |
| GLU 29 | NTc.Cm1 | SER 179 | 4.46x46 | VdWContact |
| SER 31 | CX.5 | ARG 30 | - | HBAcceptor |
| SER 31 | CX.5 | ARG 30 | - | VdWContact |
| SER 31 | CX.5 | SER 178 | 4.45x45 | HBDonor |
| SER 31 | CX.5 | SER 178 | 4.45x45 | VdWContact |
| PRO 32 | cxb1.1 | GLN 176 | 4.43x43 | Hydrophobic |
| PRO 32 | cxb1.1 | GLN 176 | 4.43x43 | VdWContact |
| PRO 32 | cxb1.1 | SER 178 | 4.45x45 | VdWContact |
| GLN 33 | cxb1.2 | ARG 185 | 4.52x52 | VdWContact |
| CYS 34 | cxb1.5 | ARG 30 | - | Anionic |
| PRO 35 | cxb1.6 | ASN 266 | 6.38x38 | VdWContact |
| LYS 36 | cxb1.7 | ASN 266 | 6.38x38 | VdWContact |
| LYS 36 | cxb1.7 | ILE 269 | 6.41x41 | Hydrophobic |
| LYS 36 | cxb1.7 | ILE 269 | 6.41x41 | VdWContact |
| ILE 40 | cxb1.14 | LEU 23 | - | Hydrophobic |
| ILE 40 | cxb1.14 | LEU 23 | - | VdWContact |
| ARG 45 | B1.3 | TYR 17 | - | Cationic |
| ARG 45 | B1.3 | TYR 17 | - | HBDonor |
| ARG 45 | B1.3 | TYR 17 | - | VdWContact |
| ARG 47 | B1.5 | VAL 15 | - | VdWContact |
| ARG 47 | B1.5 | TYR 17 | - | VdWContact |
| ARG 47 | B1.5 | PHE 20 | - | VdWContact |
| GLN 48 | B1.6 | LEU 23 | - | Hydrophobic |
| GLN 48 | B1.6 | LEU 23 | - | VdWContact |
| ILE 49 | B1.7 | PHE 20 | - | Hydrophobic |
| ILE 49 | B1.7 | PHE 20 | - | VdWContact |
