Predicted complex interactions
CCL15_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 127
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 17 | NTc.Cm36 | ARG 37 | - | HBAcceptor |
| LEU 17 | NTc.Cm36 | ARG 37 | - | VdWContact |
| VAL 21 | NTc.Cm32 | ASP 39 | 1.25x25 | VdWContact |
| VAL 21 | NTc.Cm32 | VAL 42 | 1.28x28 | Hydrophobic |
| VAL 21 | NTc.Cm32 | VAL 42 | 1.28x28 | VdWContact |
| VAL 22 | NTc.Cm31 | ASN 194 | - | VdWContact |
| LEU 23 | NTc.Cm30 | VAL 42 | 1.28x28 | Hydrophobic |
| LEU 23 | NTc.Cm30 | VAL 42 | 1.28x28 | VdWContact |
| LEU 23 | NTc.Cm30 | LYS 46 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm30 | LEU 49 | 1.35x35 | Hydrophobic |
| LEU 23 | NTc.Cm30 | VAL 106 | 2.64x64 | Hydrophobic |
| LEU 23 | NTc.Cm30 | GLN 295 | 7.36x35 | Hydrophobic |
| LEU 23 | NTc.Cm30 | GLN 295 | 7.36x35 | VdWContact |
| ASN 24 | NTc.Cm29 | SER 105 | 2.63x63 | VdWContact |
| ASN 24 | NTc.Cm29 | TRP 110 | 23.50x50 | VdWContact |
| ASN 24 | NTc.Cm29 | CYS 195 | 45.50x50 | HBAcceptor |
| ASN 24 | NTc.Cm29 | CYS 195 | 45.50x50 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 53 | 1.39x39 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 53 | 1.39x39 | VdWContact |
| PHE 26 | NTc.Cm27 | PHE 95 | 2.53x53 | Hydrophobic |
| PHE 26 | NTc.Cm27 | PHE 95 | 2.53x53 | VdWContact |
| PHE 26 | NTc.Cm27 | LEU 99 | 2.57x57 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 102 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TRP 102 | 2.60x60 | PiStacking |
| PHE 26 | NTc.Cm27 | TRP 102 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 124 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 124 | 3.32x32 | PiStacking |
| PHE 26 | NTc.Cm27 | TYR 124 | 3.32x32 | VdWContact |
| PHE 26 | NTc.Cm27 | GLU 298 | 7.39x38 | VdWContact |
| PHE 26 | NTc.Cm27 | PHE 302 | 7.43x42 | Hydrophobic |
| PHE 26 | NTc.Cm27 | PHE 302 | 7.43x42 | VdWContact |
| HIS 27 | NTc.Cm26 | ARG 211 | 5.39x40 | VdWContact |
| HIS 27 | NTc.Cm26 | TYR 266 | 6.51x51 | HBDonor |
| HIS 27 | NTc.Cm26 | TYR 266 | 6.51x51 | Hydrophobic |
| HIS 27 | NTc.Cm26 | TYR 266 | 6.51x51 | VdWContact |
| HIS 27 | NTc.Cm26 | LEU 270 | 6.55x55 | Hydrophobic |
| HIS 27 | NTc.Cm26 | LEU 270 | 6.55x55 | VdWContact |
| HIS 27 | NTc.Cm26 | LEU 294 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | LEU 294 | 7.35x34 | VdWContact |
| HIS 27 | NTc.Cm26 | GLU 298 | 7.39x38 | VdWContact |
| PHE 28 | NTc.Cm25 | ASN 194 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | HIS 196 | 45.51x51 | Hydrophobic |
| PHE 28 | NTc.Cm25 | HIS 196 | 45.51x51 | PiStacking |
| ALA 29 | NTc.Cm24 | LYS 38 | 1.24x24 | Hydrophobic |
| ALA 29 | NTc.Cm24 | ASP 291 | 7.32x31 | Hydrophobic |
| ALA 30 | NTc.Cm23 | LYS 38 | 1.24x24 | VdWContact |
| ASP 31 | NTc.Cm22 | LEU 35 | - | Hydrophobic |
| ASP 31 | NTc.Cm22 | LEU 35 | - | VdWContact |
| ASP 31 | NTc.Cm22 | CYS 36 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ARG 37 | - | VdWContact |
| ASP 31 | NTc.Cm22 | LYS 38 | 1.24x24 | HBAcceptor |
| ASP 31 | NTc.Cm22 | LYS 38 | 1.24x24 | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 36 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 36 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 36 | - | VdWContact |
| CYS 33 | NTc.Cm20 | MET 34 | - | VdWContact |
| THR 34 | NTc.Cm19 | MET 34 | - | HBDonor |
| THR 34 | NTc.Cm19 | MET 34 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 36 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 36 | - | VdWContact |
| SER 35 | NTc.Cm18 | MET 34 | - | VdWContact |
| TYR 36 | NTc.Cm17 | MET 34 | - | VdWContact |
| ILE 37 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | LEU 28 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | MET 34 | - | Hydrophobic |
| ILE 37 | NTc.Cm16 | MET 34 | - | VdWContact |
| SER 38 | NTc.Cm15 | TYR 27 | - | HBDonor |
| SER 38 | NTc.Cm15 | TYR 27 | - | VdWContact |
| GLN 39 | NTc.Cm14 | TYR 24 | - | Hydrophobic |
| GLN 39 | NTc.Cm14 | TYR 24 | - | VdWContact |
| GLN 39 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| SER 40 | NTc.Cm13 | TYR 24 | - | HBAcceptor |
| SER 40 | NTc.Cm13 | TYR 24 | - | VdWContact |
| PRO 42 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 24 | - | VdWContact |
| LEU 45 | NTc.Cm8 | TYR 24 | - | Hydrophobic |
| LEU 45 | NTc.Cm8 | TYR 25 | - | HBAcceptor |
| LEU 45 | NTc.Cm8 | TYR 25 | - | Hydrophobic |
| MET 46 | NTc.Cm7 | TYR 24 | - | Hydrophobic |
| MET 46 | NTc.Cm7 | LEU 28 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | ASN 188 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | ASN 188 | - | VdWContact |
| THR 52 | NTc.Cm1 | HIS 202 | 5.30x31 | HBAcceptor |
| THR 52 | NTc.Cm1 | HIS 202 | 5.30x31 | VdWContact |
| SER 53 | CX.1 | HIS 196 | 45.51x51 | HBDonor |
| SER 53 | CX.1 | HIS 196 | 45.51x51 | VdWContact |
| SER 53 | CX.1 | HIS 202 | 5.30x31 | VdWContact |
| SER 54 | CX.5 | ASP 198 | - | VdWContact |
| SER 54 | CX.5 | GLY 201 | - | VdWContact |
| GLU 55 | cxb1.1 | LYS 207 | 5.35x36 | Anionic |
| GLU 55 | cxb1.1 | LYS 207 | 5.35x36 | HBAcceptor |
| GLU 55 | cxb1.1 | LYS 207 | 5.35x36 | VdWContact |
| GLU 55 | cxb1.1 | ARG 211 | 5.39x40 | Anionic |
| CYS 56 | cxb1.2 | HIS 202 | 5.30x31 | Hydrophobic |
| CYS 56 | cxb1.2 | HIS 202 | 5.30x31 | VdWContact |
| SER 57 | cxb1.5 | ASP 277 | 6.62x62 | VdWContact |
| SER 57 | cxb1.5 | GLN 279 | 6.64x64 | HBAcceptor |
| SER 57 | cxb1.5 | GLN 279 | 6.64x64 | VdWContact |
| LYS 58 | cxb1.6 | HIS 202 | 5.30x31 | VdWContact |
| LYS 58 | cxb1.6 | GLN 279 | 6.64x64 | VdWContact |
| PRO 59 | cxb1.7 | HIS 202 | 5.30x31 | Hydrophobic |
| PRO 59 | cxb1.7 | HIS 202 | 5.30x31 | VdWContact |
| ILE 62 | cxb1.11 | LEU 35 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 25 | - | Hydrophobic |
| THR 65 | cxb1.16 | TYR 25 | - | VdWContact |
| THR 65 | cxb1.16 | LEU 28 | - | Hydrophobic |
| LYS 67 | B1.2 | TYR 25 | - | Hydrophobic |
| LYS 67 | B1.2 | TYR 25 | - | VdWContact |
| ARG 69 | B1.4 | TYR 25 | - | VdWContact |
| ARG 69 | B1.4 | ASP 29 | - | Cationic |
| ARG 69 | B1.4 | ASP 29 | - | HBDonor |
| ARG 69 | B1.4 | ASP 29 | - | VdWContact |
| GLN 70 | B1.5 | LEU 35 | - | Hydrophobic |
| GLN 70 | B1.5 | LEU 35 | - | VdWContact |
| GLN 70 | B1.5 | ARG 37 | - | HBAcceptor |
| GLN 70 | B1.5 | ARG 37 | - | VdWContact |
| VAL 71 | B1.6 | LEU 28 | - | Hydrophobic |
| VAL 71 | B1.6 | LEU 28 | - | VdWContact |
| VAL 71 | B1.6 | MET 34 | - | Hydrophobic |
| CYS 72 | B1.7 | MET 34 | - | Hydrophobic |
| CYS 72 | B1.7 | MET 34 | - | VdWContact |
| TYR 90 | b2b3.12 | PRO 189 | - | Hydrophobic |
| TYR 90 | b2b3.12 | LYS 190 | - | HBAcceptor |
| TYR 90 | b2b3.12 | LYS 190 | - | VdWContact |
| SER 91 | B3.1 | LYS 190 | - | VdWContact |
| ILE 92 | B3.2 | PRO 189 | - | Hydrophobic |
| ILE 92 | B3.2 | PRO 189 | - | VdWContact |
