Predicted complex interactions
CCL22_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 96
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | TYR 112 | 2.58x58 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 255 | - | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 284 | 6.56x56 | HBAcceptor |
| GLY 1 | NTc.Cm35 | TYR 284 | 6.56x56 | HBDonor |
| GLY 1 | NTc.Cm35 | TYR 284 | 6.56x56 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 288 | 6.60x60 | CationPi |
| GLY 1 | NTc.Cm35 | TYR 288 | 6.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | TRP 90 | 12.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 90 | 12.51x51 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 109 | 2.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm34 | PHE 109 | 2.55x55 | VdWContact |
| TYR 3 | NTc.Cm33 | PHE 109 | 2.55x55 | PiStacking |
| TYR 3 | NTc.Cm33 | TYR 112 | 2.58x58 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LYS 113 | 2.59x59 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 169 | 34.58x58 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 169 | 34.58x58 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLU 169 | 34.58x58 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 188 | 4.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 188 | 4.55x55 | VdWContact |
| TYR 3 | NTc.Cm33 | PHE 196 | 4.63x64 | Hydrophobic |
| TYR 3 | NTc.Cm33 | PHE 196 | 4.63x64 | VdWContact |
| TYR 3 | NTc.Cm33 | GLN 200 | - | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLN 200 | - | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 284 | 6.56x56 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 284 | 6.56x56 | VdWContact |
| GLY 4 | NTc.Cm32 | LYS 33 | - | HBAcceptor |
| GLY 4 | NTc.Cm32 | TYR 284 | 6.56x56 | HBDonor |
| GLY 4 | NTc.Cm32 | TYR 284 | 6.56x56 | VdWContact |
| ASN 6 | NTc.Cm30 | LYS 33 | - | VdWContact |
| ASN 6 | NTc.Cm30 | ARG 185 | 4.52x52 | Hydrophobic |
| MET 7 | NTc.Cm29 | THR 190 | 4.57x57 | Hydrophobic |
| MET 7 | NTc.Cm29 | THR 190 | 4.57x57 | VdWContact |
| GLU 8 | NTc.Cm28 | LYS 26 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | LYS 26 | - | VdWContact |
| GLU 8 | NTc.Cm28 | VAL 29 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | ARG 30 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | LYS 33 | - | Anionic |
| GLU 8 | NTc.Cm28 | LYS 33 | - | HBAcceptor |
| GLU 8 | NTc.Cm28 | LYS 33 | - | VdWContact |
| GLU 8 | NTc.Cm28 | ASN 281 | 6.53x53 | Hydrophobic |
| GLU 8 | NTc.Cm28 | ASN 281 | 6.53x53 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 30 | - | Anionic |
| ASP 9 | NTc.Cm27 | ARG 30 | - | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 30 | - | VdWContact |
| ASP 9 | NTc.Cm27 | SER 178 | 4.45x45 | VdWContact |
| ASP 9 | NTc.Cm27 | ARG 185 | 4.52x52 | Anionic |
| ASP 9 | NTc.Cm27 | ARG 185 | 4.52x52 | HBAcceptor |
| ASP 9 | NTc.Cm27 | ARG 185 | 4.52x52 | VdWContact |
| VAL 11 | NTc.Cm25 | LEU 23 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | LEU 23 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLU 21 | - | HBDonor |
| ARG 14 | NTc.Cm22 | GLU 21 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ILE 269 | 6.41x41 | Hydrophobic |
| ARG 14 | NTc.Cm22 | SER 272 | 6.44x44 | HBDonor |
| ARG 14 | NTc.Cm22 | SER 272 | 6.44x44 | VdWContact |
| ARG 14 | NTc.Cm22 | THR 273 | 6.45x45 | HBDonor |
| ARG 14 | NTc.Cm22 | THR 273 | 6.45x45 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 274 | 6.46x46 | VdWContact |
| ARG 14 | NTc.Cm22 | SER 277 | 6.49x49 | VdWContact |
| ASP 15 | NTc.Cm21 | GLU 21 | - | HBDonor |
| ASP 15 | NTc.Cm21 | GLU 21 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | GLU 21 | - | VdWContact |
| VAL 17 | NTc.Cm19 | PHE 20 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | PHE 20 | - | VdWContact |
| TYR 19 | NTc.Cm17 | LEU 19 | - | Hydrophobic |
| ARG 20 | NTc.Cm16 | ASP 6 | - | Cationic |
| ARG 20 | NTc.Cm16 | ASP 6 | - | HBDonor |
| ARG 20 | NTc.Cm16 | ASP 6 | - | VdWContact |
| ARG 20 | NTc.Cm16 | ILE 9 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | VAL 15 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | PHE 20 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | ILE 9 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | VAL 15 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | ILE 9 | - | HBDonor |
| ARG 24 | NTc.Cm12 | ILE 9 | - | VdWContact |
| ARG 24 | NTc.Cm12 | GLY 10 | - | HBDonor |
| ARG 24 | NTc.Cm12 | GLY 10 | - | VdWContact |
| ARG 24 | NTc.Cm12 | ASP 11 | - | Cationic |
| ARG 24 | NTc.Cm12 | ASP 11 | - | HBDonor |
| ARG 24 | NTc.Cm12 | ASP 11 | - | VdWContact |
| VAL 25 | NTc.Cm11 | VAL 15 | - | Hydrophobic |
| SER 33 | NTc.Cm3 | SER 179 | 4.46x46 | HBAcceptor |
| SER 33 | NTc.Cm3 | SER 179 | 4.46x46 | VdWContact |
| VAL 42 | cxb1.7 | LEU 23 | - | Hydrophobic |
| THR 45 | cxb1.11 | TYR 17 | - | Hydrophobic |
| THR 45 | cxb1.11 | TYR 17 | - | VdWContact |
| ARG 47 | cxb1.15 | TYR 17 | - | Hydrophobic |
| ARG 47 | cxb1.15 | TYR 17 | - | VdWContact |
| LYS 49 | B1.1 | TYR 17 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 17 | - | VdWContact |
| GLU 50 | B1.2 | LEU 23 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 23 | - | VdWContact |
| ILE 51 | B1.3 | TYR 17 | - | Hydrophobic |
| ILE 51 | B1.3 | PHE 20 | - | Hydrophobic |
| ILE 51 | B1.3 | PHE 20 | - | VdWContact |
| CYS 52 | B1.4 | LEU 23 | - | VdWContact |
