Predicted complex interactions
CCL23_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 14 | NTc.Cm57 | GLU 191 | 4.58x59 | Cationic |
| LYS 14 | NTc.Cm57 | GLU 191 | 4.58x59 | HBDonor |
| LYS 14 | NTc.Cm57 | GLU 191 | 4.58x59 | Hydrophobic |
| LYS 14 | NTc.Cm57 | GLU 191 | 4.58x59 | VdWContact |
| LEU 17 | NTc.Cm54 | GLU 191 | 4.58x59 | Hydrophobic |
| LEU 17 | NTc.Cm54 | GLU 191 | 4.58x59 | VdWContact |
| LEU 17 | NTc.Cm54 | VAL 193 | 4.60x61 | Hydrophobic |
| LEU 17 | NTc.Cm54 | VAL 193 | 4.60x61 | VdWContact |
| ASN 19 | NTc.Cm52 | GLU 194 | 4.61x62 | HBDonor |
| ASN 19 | NTc.Cm52 | GLU 194 | 4.61x62 | VdWContact |
| PRO 20 | NTc.Cm51 | ASN 266 | 6.38x38 | VdWContact |
| PRO 20 | NTc.Cm51 | PHE 267 | 6.39x39 | VdWContact |
| PRO 20 | NTc.Cm51 | ILE 269 | 6.41x41 | Hydrophobic |
| PRO 20 | NTc.Cm51 | ILE 269 | 6.41x41 | VdWContact |
| VAL 21 | NTc.Cm50 | THR 190 | 4.57x57 | VdWContact |
| VAL 21 | NTc.Cm50 | VAL 193 | 4.60x61 | Hydrophobic |
| VAL 21 | NTc.Cm50 | VAL 193 | 4.60x61 | VdWContact |
| LEU 22 | NTc.Cm49 | ILE 197 | 4.64x65 | Hydrophobic |
| LEU 22 | NTc.Cm49 | ILE 197 | 4.64x65 | VdWContact |
| LEU 22 | NTc.Cm49 | THR 263 | 6.35x35 | Hydrophobic |
| LEU 22 | NTc.Cm49 | THR 263 | 6.35x35 | VdWContact |
| LEU 22 | NTc.Cm49 | ASN 266 | 6.38x38 | Hydrophobic |
| LEU 22 | NTc.Cm49 | ASN 266 | 6.38x38 | VdWContact |
| LEU 22 | NTc.Cm49 | PHE 267 | 6.39x39 | Hydrophobic |
| LEU 22 | NTc.Cm49 | PHE 267 | 6.39x39 | VdWContact |
| LEU 23 | NTc.Cm48 | THR 190 | 4.57x57 | Hydrophobic |
| LEU 23 | NTc.Cm48 | THR 190 | 4.57x57 | VdWContact |
| LEU 23 | NTc.Cm48 | PHE 196 | 4.63x64 | Hydrophobic |
| LEU 23 | NTc.Cm48 | ASN 266 | 6.38x38 | HBAcceptor |
| LEU 23 | NTc.Cm48 | ASN 266 | 6.38x38 | VdWContact |
| ASP 24 | NTc.Cm47 | GLN 200 | - | VdWContact |
| ASP 24 | NTc.Cm47 | VAL 259 | 6.31x31 | Hydrophobic |
| ASP 24 | NTc.Cm47 | VAL 259 | 6.31x31 | VdWContact |
| PHE 26 | NTc.Cm45 | PHE 109 | 2.55x55 | Hydrophobic |
| PHE 26 | NTc.Cm45 | PHE 109 | 2.55x55 | VdWContact |
| PHE 26 | NTc.Cm45 | TYR 112 | 2.58x58 | Hydrophobic |
| PHE 26 | NTc.Cm45 | TYR 112 | 2.58x58 | VdWContact |
| PHE 26 | NTc.Cm45 | LYS 113 | 2.59x59 | VdWContact |
| PHE 26 | NTc.Cm45 | LEU 188 | 4.55x55 | Hydrophobic |
| PHE 26 | NTc.Cm45 | LEU 188 | 4.55x55 | VdWContact |
| PHE 26 | NTc.Cm45 | TYR 255 | - | Hydrophobic |
| PHE 26 | NTc.Cm45 | TYR 255 | - | VdWContact |
| PHE 26 | NTc.Cm45 | TYR 284 | 6.56x56 | Hydrophobic |
| PHE 26 | NTc.Cm45 | TYR 284 | 6.56x56 | PiStacking |
| PHE 26 | NTc.Cm45 | TYR 284 | 6.56x56 | VdWContact |
| PHE 26 | NTc.Cm45 | TYR 288 | 6.60x60 | Hydrophobic |
| HIS 27 | NTc.Cm44 | TYR 41 | - | Hydrophobic |
| HIS 27 | NTc.Cm44 | TRP 90 | 12.51x51 | Hydrophobic |
| HIS 27 | NTc.Cm44 | TRP 90 | 12.51x51 | PiStacking |
| HIS 27 | NTc.Cm44 | TRP 90 | 12.51x51 | VdWContact |
| HIS 27 | NTc.Cm44 | TYR 288 | 6.60x60 | Hydrophobic |
| ALA 28 | NTc.Cm43 | LYS 33 | - | HBAcceptor |
| ALA 28 | NTc.Cm43 | LYS 33 | - | VdWContact |
| THR 29 | NTc.Cm42 | ARG 185 | 4.52x52 | Hydrophobic |
| SER 30 | NTc.Cm41 | LYS 26 | - | VdWContact |
| SER 30 | NTc.Cm41 | ARG 30 | - | HBAcceptor |
| SER 30 | NTc.Cm41 | ARG 30 | - | VdWContact |
| SER 30 | NTc.Cm41 | ASN 281 | 6.53x53 | VdWContact |
| ASP 32 | NTc.Cm39 | LEU 23 | - | Hydrophobic |
| ASP 32 | NTc.Cm39 | CYS 24 | - | VdWContact |
| ASP 32 | NTc.Cm39 | SER 25 | - | VdWContact |
| ASP 32 | NTc.Cm39 | LYS 26 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | LYS 26 | - | VdWContact |
| ASP 32 | NTc.Cm39 | ARG 30 | - | Anionic |
| ASP 32 | NTc.Cm39 | ARG 30 | - | HBAcceptor |
| ASP 32 | NTc.Cm39 | ARG 30 | - | VdWContact |
| ASP 32 | NTc.Cm39 | SER 180 | 4.47x47 | VdWContact |
| CYS 33 | NTc.Cm38 | CYS 24 | - | HBAcceptor |
| CYS 33 | NTc.Cm38 | CYS 24 | - | HBDonor |
| CYS 33 | NTc.Cm38 | CYS 24 | - | VdWContact |
| ILE 35 | NTc.Cm36 | SER 22 | - | HBDonor |
| ILE 35 | NTc.Cm36 | SER 22 | - | VdWContact |
| ILE 35 | NTc.Cm36 | CYS 24 | - | Hydrophobic |
| SER 36 | NTc.Cm35 | SER 22 | - | VdWContact |
| PRO 39 | NTc.Cm32 | LEU 19 | - | Hydrophobic |
| ARG 40 | NTc.Cm31 | THR 14 | - | HBDonor |
| ARG 40 | NTc.Cm31 | THR 14 | - | VdWContact |
| ILE 42 | NTc.Cm29 | VAL 15 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | PHE 20 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | SER 179 | 4.46x46 | VdWContact |
| GLU 52 | NTc.Cm19 | SER 179 | 4.46x46 | HBAcceptor |
| GLU 52 | NTc.Cm19 | SER 179 | 4.46x46 | VdWContact |
| ASN 54 | NTc.Cm17 | GLN 176 | 4.43x43 | HBDonor |
| ASN 54 | NTc.Cm17 | GLN 176 | 4.43x43 | VdWContact |
| SER 55 | NTc.Cm16 | GLN 176 | 4.43x43 | VdWContact |
| SER 55 | NTc.Cm16 | THR 190 | 4.57x57 | HBAcceptor |
| SER 55 | NTc.Cm16 | THR 190 | 4.57x57 | HBDonor |
| SER 55 | NTc.Cm16 | THR 190 | 4.57x57 | VdWContact |
| LYS 59 | NTc.Cm12 | ILE 269 | 6.41x41 | Hydrophobic |
| LYS 59 | NTc.Cm12 | ILE 269 | 6.41x41 | VdWContact |
| ILE 63 | NTc.Cm8 | LEU 23 | - | Hydrophobic |
| ILE 63 | NTc.Cm8 | LEU 23 | - | VdWContact |
| ARG 70 | NTc.Cm1 | TYR 17 | - | CationPi |
| ARG 70 | NTc.Cm1 | TYR 17 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | TYR 17 | - | VdWContact |
| ARG 70 | NTc.Cm1 | PHE 20 | - | Hydrophobic |
| ARG 71 | CX.1 | PHE 20 | - | VdWContact |
| ARG 71 | CX.1 | LEU 23 | - | Hydrophobic |
| ARG 71 | CX.1 | SER 180 | 4.47x47 | VdWContact |
| PHE 72 | CX.5 | PHE 20 | - | Hydrophobic |
| PHE 72 | CX.5 | PHE 20 | - | VdWContact |
| CYS 73 | cxb1.1 | SER 22 | - | HBDonor |
| CYS 73 | cxb1.1 | SER 22 | - | VdWContact |
