Predicted complex interactions
CCL27_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 82
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 5 | NTc.Cm28 | SER 180 | 4.47x47 | VdWContact |
| SER 6 | NTc.Cm27 | SER 180 | 4.47x47 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 26 | - | HBAcceptor |
| THR 7 | NTc.Cm26 | LYS 26 | - | VdWContact |
| THR 7 | NTc.Cm26 | LYS 27 | - | VdWContact |
| THR 7 | NTc.Cm26 | ARG 30 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | ARG 30 | - | VdWContact |
| THR 7 | NTc.Cm26 | SER 180 | 4.47x47 | VdWContact |
| THR 7 | NTc.Cm26 | GLU 181 | 4.48x48 | Hydrophobic |
| ALA 8 | NTc.Cm25 | LEU 23 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | LEU 23 | - | VdWContact |
| ALA 8 | NTc.Cm25 | CYS 24 | - | VdWContact |
| ALA 8 | NTc.Cm25 | SER 180 | 4.47x47 | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 24 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 24 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 24 | - | VdWContact |
| CYS 9 | NTc.Cm24 | LYS 26 | - | Anionic |
| CYS 9 | NTc.Cm24 | LYS 26 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | CYS 24 | - | Hydrophobic |
| THR 11 | NTc.Cm22 | SER 272 | 6.44x44 | HBAcceptor |
| THR 11 | NTc.Cm22 | SER 272 | 6.44x44 | VdWContact |
| THR 11 | NTc.Cm22 | CYS 274 | 6.46x46 | VdWContact |
| GLN 12 | NTc.Cm21 | GLU 21 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | GLU 21 | - | VdWContact |
| GLN 12 | NTc.Cm21 | SER 272 | 6.44x44 | HBDonor |
| GLN 12 | NTc.Cm21 | SER 272 | 6.44x44 | VdWContact |
| LEU 13 | NTc.Cm20 | ASN 268 | 6.40x40 | VdWContact |
| TYR 14 | NTc.Cm19 | LEU 19 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 20 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 20 | - | PiStacking |
| TYR 14 | NTc.Cm19 | GLU 21 | - | VdWContact |
| ARG 15 | NTc.Cm18 | ASN 268 | 6.40x40 | VdWContact |
| LEU 18 | NTc.Cm15 | PHE 20 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | PHE 20 | - | VdWContact |
| LYS 21 | NTc.Cm12 | ASP 11 | - | Cationic |
| LYS 21 | NTc.Cm12 | ASP 11 | - | HBDonor |
| LYS 21 | NTc.Cm12 | ASP 11 | - | VdWContact |
| LYS 21 | NTc.Cm12 | THR 13 | - | HBDonor |
| LYS 21 | NTc.Cm12 | THR 13 | - | VdWContact |
| LYS 21 | NTc.Cm12 | VAL 15 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | VAL 15 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | VAL 15 | - | VdWContact |
| LEU 22 | NTc.Cm11 | TYR 17 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | PHE 20 | - | Hydrophobic |
| LEU 22 | NTc.Cm11 | PHE 20 | - | VdWContact |
| GLU 30 | NTc.Cm3 | SER 179 | 4.46x46 | VdWContact |
| GLU 33 | CX.1 | GLN 176 | 4.43x43 | Hydrophobic |
| ALA 34 | CX.5 | THR 190 | 4.57x57 | Hydrophobic |
| ALA 34 | CX.5 | THR 190 | 4.57x57 | VdWContact |
| ASP 35 | cxb1.1 | GLN 176 | 4.43x43 | Hydrophobic |
| ASP 35 | cxb1.1 | SER 178 | 4.45x45 | HBAcceptor |
| ASP 35 | cxb1.1 | SER 178 | 4.45x45 | VdWContact |
| ASP 35 | cxb1.1 | SER 187 | 4.54x54 | VdWContact |
| ASP 37 | cxb1.5 | LYS 26 | - | HBAcceptor |
| ASP 37 | cxb1.5 | LYS 26 | - | VdWContact |
| ASP 37 | cxb1.5 | ARG 30 | - | Anionic |
| ASP 37 | cxb1.5 | LYS 33 | - | Anionic |
| ASP 37 | cxb1.5 | LYS 33 | - | HBAcceptor |
| ASP 37 | cxb1.5 | LYS 33 | - | VdWContact |
| ASP 37 | cxb1.5 | ARG 185 | 4.52x52 | Anionic |
| ASP 37 | cxb1.5 | ARG 185 | 4.52x52 | HBAcceptor |
| ASP 37 | cxb1.5 | ARG 185 | 4.52x52 | VdWContact |
| ASP 37 | cxb1.5 | ASN 281 | 6.53x53 | HBAcceptor |
| ASP 37 | cxb1.5 | ASN 281 | 6.53x53 | VdWContact |
| HIS 39 | cxb1.7 | LYS 26 | - | PiCation |
| HIS 39 | cxb1.7 | GLN 262 | 6.34x34 | Hydrophobic |
| HIS 39 | cxb1.7 | ASN 266 | 6.38x38 | VdWContact |
| HIS 39 | cxb1.7 | SER 277 | 6.49x49 | VdWContact |
| HIS 39 | cxb1.7 | LEU 280 | 6.52x52 | Hydrophobic |
| HIS 39 | cxb1.7 | ASN 281 | 6.53x53 | VdWContact |
| LEU 40 | cxb1.8 | ASN 268 | 6.40x40 | Hydrophobic |
| VAL 44 | cxb1.15 | LEU 23 | - | Hydrophobic |
| LEU 47 | cxb1.18 | TYR 17 | - | Hydrophobic |
| ARG 50 | B1.2 | TYR 17 | - | CationPi |
| ARG 50 | B1.2 | TYR 17 | - | VdWContact |
| SER 51 | B1.3 | LEU 23 | - | VdWContact |
| ILE 52 | B1.4 | PHE 20 | - | Hydrophobic |
| CYS 53 | B1.5 | GLU 21 | - | HBDonor |
| CYS 53 | B1.5 | GLU 21 | - | Hydrophobic |
| CYS 53 | B1.5 | GLU 21 | - | VdWContact |
| ILE 54 | B1.6 | PHE 20 | - | Hydrophobic |
| MET 87 | H.5 | GLU 191 | 4.58x59 | Hydrophobic |
