Predicted complex interactions
CCL16_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 139
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm36 | ALA 197 | 45.52x52 | Hydrophobic |
| GLN 1 | NTc.Cm36 | ALA 197 | 45.52x52 | VdWContact |
| GLN 1 | NTc.Cm36 | PHE 199 | - | Hydrophobic |
| GLN 1 | NTc.Cm36 | PHE 199 | - | VdWContact |
| GLN 1 | NTc.Cm36 | LYS 207 | 5.35x36 | Hydrophobic |
| GLN 1 | NTc.Cm36 | LYS 207 | 5.35x36 | VdWContact |
| GLN 1 | NTc.Cm36 | LEU 210 | 5.38x39 | VdWContact |
| PRO 2 | NTc.Cm35 | ASP 179 | 4.60x61 | Hydrophobic |
| PRO 2 | NTc.Cm35 | ASP 179 | 4.60x61 | VdWContact |
| PRO 2 | NTc.Cm35 | PHE 182 | 4.63x64 | Hydrophobic |
| PRO 2 | NTc.Cm35 | VAL 183 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm35 | VAL 183 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm35 | ALA 197 | 45.52x52 | Hydrophobic |
| PRO 2 | NTc.Cm35 | ALA 197 | 45.52x52 | VdWContact |
| PRO 2 | NTc.Cm35 | PHE 199 | - | Hydrophobic |
| PRO 2 | NTc.Cm35 | PHE 199 | - | VdWContact |
| PRO 2 | NTc.Cm35 | LEU 210 | 5.38x39 | VdWContact |
| LYS 3 | NTc.Cm34 | TYR 124 | 3.32x32 | Hydrophobic |
| LYS 3 | NTc.Cm34 | TYR 124 | 3.32x32 | VdWContact |
| LYS 3 | NTc.Cm34 | ASP 179 | 4.60x61 | HBDonor |
| LYS 3 | NTc.Cm34 | GLN 214 | 5.42x43 | HBDonor |
| LYS 3 | NTc.Cm34 | GLN 214 | 5.42x43 | VdWContact |
| LYS 3 | NTc.Cm34 | TYR 266 | 6.51x51 | Hydrophobic |
| LYS 3 | NTc.Cm34 | LEU 270 | 6.55x55 | VdWContact |
| VAL 4 | NTc.Cm33 | TRP 102 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm33 | TRP 102 | 2.60x60 | VdWContact |
| VAL 4 | NTc.Cm33 | VAL 183 | 4.64x65 | Hydrophobic |
| VAL 4 | NTc.Cm33 | CYS 195 | 45.50x50 | VdWContact |
| PRO 5 | NTc.Cm32 | TRP 102 | 2.60x60 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 124 | 3.32x32 | Hydrophobic |
| PRO 5 | NTc.Cm32 | GLU 298 | 7.39x38 | VdWContact |
| PRO 5 | NTc.Cm32 | PHE 302 | 7.43x42 | Hydrophobic |
| GLU 6 | NTc.Cm31 | ARG 211 | 5.39x40 | Anionic |
| GLU 6 | NTc.Cm31 | ARG 211 | 5.39x40 | HBAcceptor |
| GLU 6 | NTc.Cm31 | ARG 211 | 5.39x40 | VdWContact |
| GLU 6 | NTc.Cm31 | LEU 270 | 6.55x55 | Hydrophobic |
| GLU 6 | NTc.Cm31 | LEU 270 | 6.55x55 | VdWContact |
| GLU 6 | NTc.Cm31 | LEU 294 | 7.35x34 | Hydrophobic |
| GLU 6 | NTc.Cm31 | LEU 294 | 7.35x34 | VdWContact |
| GLU 6 | NTc.Cm31 | GLU 298 | 7.39x38 | HBDonor |
| GLU 6 | NTc.Cm31 | GLU 298 | 7.39x38 | VdWContact |
| TRP 7 | NTc.Cm30 | VAL 41 | 1.27x27 | Hydrophobic |
| TRP 7 | NTc.Cm30 | VAL 41 | 1.27x27 | VdWContact |
| TRP 7 | NTc.Cm30 | VAL 42 | 1.28x28 | Hydrophobic |
| TRP 7 | NTc.Cm30 | LEU 49 | 1.35x35 | Hydrophobic |
| TRP 7 | NTc.Cm30 | LEU 49 | 1.35x35 | VdWContact |
| TRP 7 | NTc.Cm30 | ASP 291 | 7.32x31 | Hydrophobic |
| TRP 7 | NTc.Cm30 | ASP 291 | 7.32x31 | VdWContact |
| TRP 7 | NTc.Cm30 | GLN 295 | 7.36x35 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLN 295 | 7.36x35 | VdWContact |
| VAL 8 | NTc.Cm29 | TRP 102 | 2.60x60 | Hydrophobic |
| VAL 8 | NTc.Cm29 | VAL 106 | 2.64x64 | Hydrophobic |
| VAL 8 | NTc.Cm29 | VAL 106 | 2.64x64 | VdWContact |
| ASN 9 | NTc.Cm28 | ASN 194 | - | VdWContact |
| ASN 9 | NTc.Cm28 | CYS 195 | 45.50x50 | HBDonor |
| ASN 9 | NTc.Cm28 | CYS 195 | 45.50x50 | VdWContact |
| ASN 9 | NTc.Cm28 | HIS 196 | 45.51x51 | Hydrophobic |
| ASN 9 | NTc.Cm28 | HIS 196 | 45.51x51 | VdWContact |
| SER 12 | NTc.Cm25 | LYS 38 | 1.24x24 | HBAcceptor |
| SER 12 | NTc.Cm25 | LYS 38 | 1.24x24 | VdWContact |
| SER 12 | NTc.Cm25 | ASP 39 | 1.25x25 | VdWContact |
| THR 13 | NTc.Cm24 | LEU 35 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | CYS 36 | - | VdWContact |
| CYS 14 | NTc.Cm23 | CYS 36 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | CYS 36 | - | HBDonor |
| CYS 14 | NTc.Cm23 | CYS 36 | - | VdWContact |
| CYS 14 | NTc.Cm23 | LYS 38 | 1.24x24 | Anionic |
| CYS 15 | NTc.Cm22 | MET 34 | - | VdWContact |
| LEU 16 | NTc.Cm21 | MET 34 | - | HBDonor |
| LEU 16 | NTc.Cm21 | MET 34 | - | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 36 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 284 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 284 | 7.25x24 | VdWContact |
| LYS 17 | NTc.Cm20 | MET 34 | - | Hydrophobic |
| LYS 17 | NTc.Cm20 | MET 34 | - | VdWContact |
| TYR 18 | NTc.Cm19 | MET 34 | - | VdWContact |
| TYR 19 | NTc.Cm18 | TYR 24 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | TYR 24 | - | VdWContact |
| TYR 19 | NTc.Cm18 | TYR 27 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | TYR 27 | - | VdWContact |
| TYR 19 | NTc.Cm18 | LEU 28 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | VAL 31 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | VAL 31 | - | VdWContact |
| TYR 19 | NTc.Cm18 | MET 34 | - | Hydrophobic |
| LYS 21 | NTc.Cm16 | TYR 27 | - | Hydrophobic |
| LYS 21 | NTc.Cm16 | TYR 27 | - | VdWContact |
| VAL 22 | NTc.Cm15 | TYR 24 | - | HBAcceptor |
| VAL 22 | NTc.Cm15 | TYR 24 | - | VdWContact |
| LEU 23 | NTc.Cm14 | TYR 24 | - | Hydrophobic |
| LEU 23 | NTc.Cm14 | TYR 24 | - | VdWContact |
| LEU 23 | NTc.Cm14 | LEU 28 | - | Hydrophobic |
| LEU 23 | NTc.Cm14 | LEU 28 | - | VdWContact |
| PRO 24 | NTc.Cm13 | TYR 24 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TYR 24 | - | VdWContact |
| ARG 26 | NTc.Cm11 | SER 17 | - | VdWContact |
| ARG 26 | NTc.Cm11 | SER 20 | - | HBDonor |
| ARG 26 | NTc.Cm11 | SER 20 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TYR 24 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TYR 24 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TYR 25 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | TYR 25 | - | VdWContact |
| LYS 33 | NTc.Cm4 | ASN 188 | - | VdWContact |
| ASN 36 | NTc.Cm1 | HIS 196 | 45.51x51 | HBDonor |
| ASN 36 | NTc.Cm1 | HIS 196 | 45.51x51 | VdWContact |
| HIS 38 | CX.5 | HIS 273 | 6.58x58 | HBAcceptor |
| HIS 38 | CX.5 | HIS 273 | 6.58x58 | Hydrophobic |
| HIS 38 | CX.5 | HIS 273 | 6.58x58 | VdWContact |
| HIS 38 | CX.5 | LEU 276 | 6.61x61 | Hydrophobic |
| HIS 38 | CX.5 | LEU 276 | 6.61x61 | VdWContact |
| HIS 38 | CX.5 | ASP 277 | 6.62x62 | HBDonor |
| HIS 38 | CX.5 | ASP 277 | 6.62x62 | VdWContact |
| LEU 39 | cxb1.1 | GLN 279 | 6.64x64 | VdWContact |
| ILE 43 | cxb1.7 | LEU 35 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 25 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 25 | - | VdWContact |
| THR 46 | cxb1.11 | LEU 28 | - | Hydrophobic |
| LYS 47 | cxb1.14 | TYR 25 | - | VdWContact |
| ARG 48 | cxb1.15 | PHE 22 | - | VdWContact |
| ARG 48 | cxb1.15 | TYR 25 | - | CationPi |
| ARG 48 | cxb1.15 | TYR 25 | - | Hydrophobic |
| ARG 48 | cxb1.15 | TYR 25 | - | VdWContact |
| ARG 50 | B1.1 | TYR 25 | - | VdWContact |
| ARG 50 | B1.1 | ASP 29 | - | Cationic |
| ARG 50 | B1.1 | ASP 29 | - | HBDonor |
| ARG 50 | B1.1 | ASP 29 | - | VdWContact |
| GLU 51 | B1.2 | LEU 35 | - | Hydrophobic |
| GLU 51 | B1.2 | LEU 35 | - | VdWContact |
| GLU 51 | B1.2 | ARG 37 | - | Anionic |
| VAL 52 | B1.3 | LEU 28 | - | Hydrophobic |
| VAL 52 | B1.3 | LEU 28 | - | VdWContact |
| VAL 52 | B1.3 | VAL 31 | - | Hydrophobic |
| CYS 53 | B1.4 | MET 34 | - | Hydrophobic |
| CYS 53 | B1.4 | LEU 35 | - | VdWContact |
| LEU 72 | b2b3.11 | ASN 188 | - | VdWContact |
| PRO 74 | B3.1 | PRO 189 | - | Hydrophobic |
| PRO 74 | B3.1 | PRO 189 | - | VdWContact |
| ARG 76 | B3.3 | ARG 37 | - | VdWContact |
| LEU 78 | b3h.1 | ASP 39 | 1.25x25 | Hydrophobic |
| LEU 78 | b3h.1 | ASP 39 | 1.25x25 | VdWContact |
