Predicted complex interactions
CCL5_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 80
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm32 | TYR 41 | - | VdWContact |
| SER 1 | NTc.Cm32 | TRP 90 | 12.51x51 | VdWContact |
| SER 1 | NTc.Cm32 | TYR 284 | 6.56x56 | VdWContact |
| SER 1 | NTc.Cm32 | TYR 288 | 6.60x60 | VdWContact |
| PRO 2 | NTc.Cm31 | TRP 90 | 12.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TRP 90 | 12.51x51 | VdWContact |
| PRO 2 | NTc.Cm31 | PHE 109 | 2.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm31 | PHE 109 | 2.55x55 | VdWContact |
| PRO 2 | NTc.Cm31 | TYR 112 | 2.58x58 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 112 | 2.58x58 | VdWContact |
| TYR 3 | NTc.Cm30 | LEU 188 | 4.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm30 | LEU 188 | 4.55x55 | VdWContact |
| TYR 3 | NTc.Cm30 | PHE 196 | 4.63x64 | Hydrophobic |
| TYR 3 | NTc.Cm30 | PHE 196 | 4.63x64 | VdWContact |
| TYR 3 | NTc.Cm30 | TYR 284 | 6.56x56 | Hydrophobic |
| TYR 3 | NTc.Cm30 | TYR 284 | 6.56x56 | VdWContact |
| SER 4 | NTc.Cm29 | LYS 33 | - | HBAcceptor |
| SER 4 | NTc.Cm29 | LYS 33 | - | VdWContact |
| SER 5 | NTc.Cm28 | ASN 281 | 6.53x53 | VdWContact |
| SER 5 | NTc.Cm28 | ASP 285 | 6.57x57 | HBDonor |
| SER 5 | NTc.Cm28 | ASP 285 | 6.57x57 | VdWContact |
| ASP 6 | NTc.Cm27 | LYS 26 | - | HBAcceptor |
| ASP 6 | NTc.Cm27 | LYS 26 | - | VdWContact |
| ASP 6 | NTc.Cm27 | ASN 281 | 6.53x53 | HBAcceptor |
| ASP 6 | NTc.Cm27 | ASN 281 | 6.53x53 | VdWContact |
| THR 7 | NTc.Cm26 | LYS 26 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | LYS 26 | - | VdWContact |
| THR 7 | NTc.Cm26 | VAL 29 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | ARG 30 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | ARG 30 | - | VdWContact |
| THR 7 | NTc.Cm26 | ARG 185 | 4.52x52 | HBAcceptor |
| THR 7 | NTc.Cm26 | ARG 185 | 4.52x52 | VdWContact |
| PRO 9 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| PRO 9 | NTc.Cm24 | LEU 23 | - | VdWContact |
| PRO 9 | NTc.Cm24 | CYS 24 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 24 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 24 | - | VdWContact |
| PHE 12 | NTc.Cm21 | SER 272 | 6.44x44 | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 274 | 6.46x46 | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 274 | 6.46x46 | VdWContact |
| PHE 12 | NTc.Cm21 | SER 277 | 6.49x49 | VdWContact |
| ALA 13 | NTc.Cm20 | GLU 21 | - | Hydrophobic |
| ALA 13 | NTc.Cm20 | GLU 21 | - | VdWContact |
| ILE 15 | NTc.Cm18 | PHE 20 | - | Hydrophobic |
| ILE 15 | NTc.Cm18 | PHE 20 | - | VdWContact |
| ILE 15 | NTc.Cm18 | GLU 21 | - | VdWContact |
| LEU 19 | NTc.Cm14 | VAL 15 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 17 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | PHE 20 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 8 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 8 | - | VdWContact |
| PRO 20 | NTc.Cm13 | VAL 15 | - | Hydrophobic |
| HIS 23 | NTc.Cm10 | VAL 15 | - | Hydrophobic |
| HIS 23 | NTc.Cm10 | VAL 15 | - | VdWContact |
| HIS 23 | NTc.Cm10 | TYR 17 | - | VdWContact |
| PHE 28 | NTc.Cm5 | LEU 23 | - | Hydrophobic |
| THR 30 | NTc.Cm3 | LEU 23 | - | Hydrophobic |
| LYS 33 | CX.1 | GLN 176 | 4.43x43 | VdWContact |
| LYS 33 | CX.1 | SER 187 | 4.54x54 | HBDonor |
| LYS 33 | CX.1 | SER 187 | 4.54x54 | VdWContact |
| LYS 33 | CX.1 | THR 190 | 4.57x57 | Hydrophobic |
| LYS 33 | CX.1 | THR 190 | 4.57x57 | VdWContact |
| ASN 36 | cxb1.2 | ILE 269 | 6.41x41 | VdWContact |
| VAL 40 | cxb1.8 | LEU 23 | - | Hydrophobic |
| VAL 40 | cxb1.8 | LEU 23 | - | VdWContact |
| THR 43 | cxb1.14 | TYR 17 | - | Hydrophobic |
| THR 43 | cxb1.14 | TYR 17 | - | VdWContact |
| LYS 45 | cxb1.16 | TYR 17 | - | Hydrophobic |
| ARG 47 | B1.2 | ASP 16 | - | Cationic |
| ARG 47 | B1.2 | TYR 17 | - | VdWContact |
| GLN 48 | B1.3 | SER 22 | - | VdWContact |
| GLN 48 | B1.3 | LEU 23 | - | HBAcceptor |
| GLN 48 | B1.3 | LEU 23 | - | Hydrophobic |
| GLN 48 | B1.3 | LEU 23 | - | VdWContact |
| VAL 49 | B1.4 | PHE 20 | - | Hydrophobic |
| CYS 50 | B1.5 | GLU 21 | - | HBDonor |
| CYS 50 | B1.5 | GLU 21 | - | VdWContact |
| CYS 50 | B1.5 | LEU 23 | - | VdWContact |
