Predicted complex interactions
CCL8_HUMAN + CCR7
SUMMARY
- Chemokine
- CCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 72
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | LEU 37 | - | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 41 | - | HBAcceptor |
| GLN 1 | NTc.Cm33 | TYR 41 | - | VdWContact |
| GLN 1 | NTc.Cm33 | TRP 90 | 12.51x51 | CationPi |
| GLN 1 | NTc.Cm33 | TRP 90 | 12.51x51 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 284 | 6.56x56 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 284 | 6.56x56 | VdWContact |
| GLN 1 | NTc.Cm33 | ASP 285 | 6.57x57 | HBDonor |
| GLN 1 | NTc.Cm33 | ASP 285 | 6.57x57 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 288 | 6.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 288 | 6.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | PHE 109 | 2.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm32 | PHE 109 | 2.55x55 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 112 | 2.58x58 | Hydrophobic |
| ASP 3 | NTc.Cm31 | LYS 33 | - | Anionic |
| ASP 3 | NTc.Cm31 | LYS 33 | - | HBAcceptor |
| ASP 3 | NTc.Cm31 | LYS 33 | - | VdWContact |
| ASP 3 | NTc.Cm31 | TRP 90 | 12.51x51 | Hydrophobic |
| ASP 3 | NTc.Cm31 | TRP 90 | 12.51x51 | VdWContact |
| ASP 3 | NTc.Cm31 | SER 93 | 2.39x39 | HBAcceptor |
| ASP 3 | NTc.Cm31 | SER 93 | 2.39x39 | VdWContact |
| ASP 3 | NTc.Cm31 | ARG 185 | 4.52x52 | Anionic |
| ASP 3 | NTc.Cm31 | CYS 186 | 4.53x53 | VdWContact |
| SER 4 | NTc.Cm30 | SER 187 | 4.54x54 | VdWContact |
| SER 4 | NTc.Cm30 | LEU 188 | 4.55x55 | VdWContact |
| VAL 5 | NTc.Cm29 | PHE 196 | 4.63x64 | Hydrophobic |
| VAL 5 | NTc.Cm29 | TYR 284 | 6.56x56 | Hydrophobic |
| SER 6 | NTc.Cm28 | LYS 33 | - | HBAcceptor |
| SER 6 | NTc.Cm28 | LYS 33 | - | VdWContact |
| ILE 7 | NTc.Cm27 | ARG 185 | 4.52x52 | Hydrophobic |
| ILE 7 | NTc.Cm27 | ARG 185 | 4.52x52 | VdWContact |
| ILE 7 | NTc.Cm27 | SER 187 | 4.54x54 | VdWContact |
| PRO 8 | NTc.Cm26 | LYS 26 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | LYS 26 | - | VdWContact |
| PRO 8 | NTc.Cm26 | VAL 29 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | ARG 30 | - | VdWContact |
| PRO 8 | NTc.Cm26 | ASN 281 | 6.53x53 | VdWContact |
| THR 10 | NTc.Cm24 | LEU 23 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | LEU 23 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 24 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 24 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 24 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 24 | - | VdWContact |
| PHE 13 | NTc.Cm21 | SER 272 | 6.44x44 | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 274 | 6.46x46 | Hydrophobic |
| PHE 13 | NTc.Cm21 | SER 277 | 6.49x49 | VdWContact |
| ASN 14 | NTc.Cm20 | GLU 21 | - | HBDonor |
| ASN 14 | NTc.Cm20 | GLU 21 | - | Hydrophobic |
| ASN 14 | NTc.Cm20 | GLU 21 | - | VdWContact |
| ILE 16 | NTc.Cm18 | PHE 20 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | PHE 20 | - | VdWContact |
| ILE 20 | NTc.Cm14 | PHE 20 | - | Hydrophobic |
| ARG 24 | NTc.Cm10 | VAL 15 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 17 | - | VdWContact |
| ILE 34 | CX.1 | THR 190 | 4.57x57 | VdWContact |
| ILE 34 | CX.1 | GLU 191 | 4.58x59 | VdWContact |
| ILE 34 | CX.1 | VAL 193 | 4.60x61 | Hydrophobic |
| ILE 34 | CX.1 | VAL 193 | 4.60x61 | VdWContact |
| PRO 37 | cxb1.2 | ILE 269 | 6.41x41 | Hydrophobic |
| PRO 37 | cxb1.2 | ILE 269 | 6.41x41 | VdWContact |
| LYS 38 | cxb1.5 | ILE 269 | 6.41x41 | Hydrophobic |
| LYS 38 | cxb1.5 | ILE 269 | 6.41x41 | VdWContact |
| ILE 42 | cxb1.10 | LEU 23 | - | Hydrophobic |
| ILE 42 | cxb1.10 | LEU 23 | - | VdWContact |
| THR 45 | cxb1.15 | TYR 17 | - | Hydrophobic |
| LYS 49 | B1.3 | TYR 17 | - | Hydrophobic |
| LYS 49 | B1.3 | TYR 17 | - | VdWContact |
| GLU 50 | B1.4 | LEU 23 | - | Hydrophobic |
| GLU 50 | B1.4 | LEU 23 | - | VdWContact |
| VAL 51 | B1.5 | PHE 20 | - | Hydrophobic |
| VAL 51 | B1.5 | PHE 20 | - | VdWContact |
