Predicted complex interactions
CXCL1_HUMAN + CCR7
SUMMARY
- Chemokine
- CXCL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 77
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 2 | NTc.Cm41 | SER 179 | 4.46x46 | VdWContact |
| SER 2 | NTc.Cm41 | SER 180 | 4.47x47 | VdWContact |
| VAL 3 | NTc.Cm40 | LEU 23 | - | Hydrophobic |
| VAL 3 | NTc.Cm40 | SER 179 | 4.46x46 | VdWContact |
| ALA 4 | NTc.Cm39 | SER 178 | 4.45x45 | HBAcceptor |
| ALA 4 | NTc.Cm39 | SER 178 | 4.45x45 | VdWContact |
| ALA 4 | NTc.Cm39 | SER 180 | 4.47x47 | HBAcceptor |
| ALA 4 | NTc.Cm39 | SER 180 | 4.47x47 | VdWContact |
| THR 5 | NTc.Cm38 | GLN 176 | 4.43x43 | Hydrophobic |
| THR 5 | NTc.Cm38 | GLN 176 | 4.43x43 | VdWContact |
| THR 5 | NTc.Cm38 | ARG 177 | 4.44x44 | HBDonor |
| THR 5 | NTc.Cm38 | ARG 177 | 4.44x44 | VdWContact |
| THR 5 | NTc.Cm38 | SER 178 | 4.45x45 | VdWContact |
| THR 5 | NTc.Cm38 | SER 179 | 4.46x46 | HBAcceptor |
| THR 5 | NTc.Cm38 | SER 179 | 4.46x46 | HBDonor |
| THR 5 | NTc.Cm38 | SER 179 | 4.46x46 | VdWContact |
| GLU 6 | NTc.Cm37 | LYS 26 | - | HBAcceptor |
| GLU 6 | NTc.Cm37 | LYS 26 | - | Hydrophobic |
| GLU 6 | NTc.Cm37 | LYS 26 | - | VdWContact |
| GLU 6 | NTc.Cm37 | ARG 30 | - | Anionic |
| GLU 6 | NTc.Cm37 | ARG 30 | - | HBAcceptor |
| GLU 6 | NTc.Cm37 | ARG 30 | - | VdWContact |
| LEU 7 | NTc.Cm36 | ARG 185 | 4.52x52 | Hydrophobic |
| LEU 7 | NTc.Cm36 | ARG 185 | 4.52x52 | VdWContact |
| ARG 8 | NTc.Cm35 | LYS 26 | - | Hydrophobic |
| ARG 8 | NTc.Cm35 | LYS 26 | - | VdWContact |
| ARG 8 | NTc.Cm35 | VAL 29 | - | VdWContact |
| ARG 8 | NTc.Cm35 | ASN 281 | 6.53x53 | HBDonor |
| ARG 8 | NTc.Cm35 | ASN 281 | 6.53x53 | VdWContact |
| ARG 8 | NTc.Cm35 | ASP 285 | 6.57x57 | Cationic |
| ARG 8 | NTc.Cm35 | ASP 285 | 6.57x57 | HBDonor |
| ARG 8 | NTc.Cm35 | ASP 285 | 6.57x57 | VdWContact |
| CYS 9 | NTc.Cm34 | LYS 26 | - | HBAcceptor |
| CYS 9 | NTc.Cm34 | LYS 26 | - | VdWContact |
| GLN 10 | NTc.Cm33 | LEU 23 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | LEU 23 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 24 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 24 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 24 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | ILE 269 | 6.41x41 | VdWContact |
| LEU 12 | NTc.Cm31 | SER 272 | 6.44x44 | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 274 | 6.46x46 | Hydrophobic |
| LEU 12 | NTc.Cm31 | CYS 274 | 6.46x46 | VdWContact |
| GLN 13 | NTc.Cm30 | GLU 21 | - | Hydrophobic |
| GLN 13 | NTc.Cm30 | GLU 21 | - | VdWContact |
| LEU 15 | NTc.Cm28 | PHE 20 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | PHE 20 | - | VdWContact |
| ILE 18 | NTc.Cm25 | TYR 17 | - | Hydrophobic |
| ILE 18 | NTc.Cm25 | TYR 17 | - | VdWContact |
| HIS 19 | NTc.Cm24 | TYR 8 | - | Hydrophobic |
| HIS 19 | NTc.Cm24 | TYR 8 | - | VdWContact |
| HIS 19 | NTc.Cm24 | ILE 9 | - | Hydrophobic |
| ASN 22 | NTc.Cm21 | TYR 17 | - | HBDonor |
| ASN 22 | NTc.Cm21 | TYR 17 | - | VdWContact |
| PRO 31 | NTc.Cm12 | VAL 193 | 4.60x61 | Hydrophobic |
| PRO 33 | NTc.Cm10 | LEU 188 | 4.55x55 | Hydrophobic |
| PRO 33 | NTc.Cm10 | LEU 188 | 4.55x55 | VdWContact |
| PRO 33 | NTc.Cm10 | PHE 196 | 4.63x64 | Hydrophobic |
| PRO 33 | NTc.Cm10 | PHE 196 | 4.63x64 | VdWContact |
| ALA 36 | NTc.Cm7 | VAL 193 | 4.60x61 | Hydrophobic |
| ALA 36 | NTc.Cm7 | VAL 193 | 4.60x61 | VdWContact |
| GLN 37 | NTc.Cm6 | ILE 269 | 6.41x41 | Hydrophobic |
| GLN 37 | NTc.Cm6 | ILE 269 | 6.41x41 | VdWContact |
| ILE 41 | NTc.Cm2 | LEU 23 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | LEU 23 | - | VdWContact |
| LEU 44 | CX.4 | TYR 17 | - | Hydrophobic |
| ARG 48 | cxb1.5 | ASP 16 | - | Cationic |
| ARG 48 | cxb1.5 | TYR 17 | - | HBDonor |
| ARG 48 | cxb1.5 | TYR 17 | - | VdWContact |
| ARG 48 | cxb1.5 | THR 18 | - | VdWContact |
| LYS 49 | cxb1.6 | LEU 23 | - | HBAcceptor |
| LYS 49 | cxb1.6 | LEU 23 | - | Hydrophobic |
| LYS 49 | cxb1.6 | LEU 23 | - | VdWContact |
| ILE 58 | B1.3 | TYR 8 | - | Hydrophobic |
| ILE 58 | B1.3 | TYR 8 | - | VdWContact |
| LYS 61 | B1.6 | VAL 4 | - | VdWContact |
| LYS 65 | b1b2.7 | THR 5 | - | Hydrophobic |
