Predicted complex interactions
CXCL10_HUMAN + CCR7
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 96
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PRO 2 | NTc.Cm28 | ILE 269 | 6.41x41 | VdWContact |
| LEU 3 | NTc.Cm27 | ILE 269 | 6.41x41 | Hydrophobic |
| LEU 3 | NTc.Cm27 | ILE 269 | 6.41x41 | VdWContact |
| ARG 5 | NTc.Cm25 | THR 190 | 4.57x57 | VdWContact |
| ARG 5 | NTc.Cm25 | ALA 265 | 6.37x37 | VdWContact |
| ARG 5 | NTc.Cm25 | ASN 266 | 6.38x38 | HBDonor |
| ARG 5 | NTc.Cm25 | ASN 266 | 6.38x38 | Hydrophobic |
| ARG 5 | NTc.Cm25 | ASN 266 | 6.38x38 | VdWContact |
| ARG 5 | NTc.Cm25 | ILE 269 | 6.41x41 | VdWContact |
| ARG 5 | NTc.Cm25 | SER 272 | 6.44x44 | HBDonor |
| ARG 5 | NTc.Cm25 | SER 272 | 6.44x44 | VdWContact |
| THR 6 | NTc.Cm24 | THR 190 | 4.57x57 | VdWContact |
| VAL 7 | NTc.Cm23 | GLN 176 | 4.43x43 | VdWContact |
| VAL 7 | NTc.Cm23 | SER 187 | 4.54x54 | VdWContact |
| VAL 7 | NTc.Cm23 | LEU 188 | 4.55x55 | VdWContact |
| VAL 7 | NTc.Cm23 | THR 190 | 4.57x57 | HBDonor |
| VAL 7 | NTc.Cm23 | THR 190 | 4.57x57 | Hydrophobic |
| VAL 7 | NTc.Cm23 | THR 190 | 4.57x57 | VdWContact |
| VAL 7 | NTc.Cm23 | PHE 196 | 4.63x64 | Hydrophobic |
| ARG 8 | NTc.Cm22 | GLN 176 | 4.43x43 | Hydrophobic |
| ARG 8 | NTc.Cm22 | GLN 176 | 4.43x43 | VdWContact |
| ARG 8 | NTc.Cm22 | ILE 189 | 4.56x56 | VdWContact |
| ARG 8 | NTc.Cm22 | GLU 191 | 4.58x59 | Cationic |
| ARG 8 | NTc.Cm22 | GLU 191 | 4.58x59 | HBDonor |
| ARG 8 | NTc.Cm22 | GLU 191 | 4.58x59 | VdWContact |
| CYS 9 | NTc.Cm21 | SER 179 | 4.46x46 | VdWContact |
| PRO 21 | NTc.Cm9 | TYR 8 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | GLU 21 | - | Cationic |
| LYS 26 | NTc.Cm4 | GLU 21 | - | HBDonor |
| LYS 26 | NTc.Cm4 | GLU 21 | - | VdWContact |
| LEU 27 | NTc.Cm3 | PHE 20 | - | Hydrophobic |
| LEU 27 | NTc.Cm3 | PHE 20 | - | VdWContact |
| ILE 29 | NTc.Cm1 | PHE 20 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | PHE 20 | - | VdWContact |
| ILE 29 | NTc.Cm1 | GLU 21 | - | HBDonor |
| ILE 29 | NTc.Cm1 | GLU 21 | - | VdWContact |
| ILE 29 | NTc.Cm1 | LEU 23 | - | Hydrophobic |
| ILE 29 | NTc.Cm1 | LEU 23 | - | VdWContact |
| ILE 30 | CX.1 | LEU 23 | - | VdWContact |
| PRO 31 | CX.4 | LEU 23 | - | VdWContact |
| PRO 31 | CX.4 | CYS 24 | - | Hydrophobic |
| PRO 31 | CX.4 | CYS 24 | - | VdWContact |
| PRO 31 | CX.4 | LYS 26 | - | Hydrophobic |
| ALA 32 | CX.5 | LEU 23 | - | Hydrophobic |
| ALA 32 | CX.5 | LEU 23 | - | VdWContact |
| ALA 32 | CX.5 | SER 25 | - | VdWContact |
| ALA 32 | CX.5 | LYS 26 | - | HBAcceptor |
| ALA 32 | CX.5 | LYS 26 | - | VdWContact |
| ALA 32 | CX.5 | ARG 30 | - | VdWContact |
| GLN 34 | cxb1.2 | ARG 30 | - | Hydrophobic |
| GLN 34 | cxb1.2 | LYS 33 | - | HBAcceptor |
| GLN 34 | cxb1.2 | LYS 33 | - | Hydrophobic |
| GLN 34 | cxb1.2 | LYS 33 | - | VdWContact |
| GLN 34 | cxb1.2 | ASP 285 | 6.57x57 | HBDonor |
| GLN 34 | cxb1.2 | ASP 285 | 6.57x57 | VdWContact |
| PRO 37 | cxb1.7 | ARG 30 | - | VdWContact |
| PRO 37 | cxb1.7 | SER 178 | 4.45x45 | VdWContact |
| PRO 37 | cxb1.7 | SER 179 | 4.46x46 | VdWContact |
| PRO 37 | cxb1.7 | SER 180 | 4.47x47 | VdWContact |
| ARG 38 | cxb1.8 | SER 179 | 4.46x46 | HBDonor |
| ARG 38 | cxb1.8 | SER 179 | 4.46x46 | VdWContact |
| ARG 38 | cxb1.8 | SER 180 | 4.47x47 | HBAcceptor |
| ARG 38 | cxb1.8 | SER 180 | 4.47x47 | VdWContact |
| VAL 39 | cxb1.10 | LEU 23 | - | Hydrophobic |
| VAL 39 | cxb1.10 | LEU 23 | - | VdWContact |
| GLU 40 | cxb1.11 | LEU 23 | - | VdWContact |
| ILE 41 | cxb1.14 | LEU 23 | - | Hydrophobic |
| LEU 65 | B2.5 | VAL 15 | - | Hydrophobic |
| LEU 65 | B2.5 | VAL 15 | - | VdWContact |
| LEU 65 | B2.5 | TYR 17 | - | Hydrophobic |
| LEU 65 | B2.5 | TYR 17 | - | VdWContact |
| LEU 65 | B2.5 | PHE 20 | - | Hydrophobic |
| LEU 65 | B2.5 | PHE 20 | - | VdWContact |
| LYS 66 | B2.6 | THR 13 | - | HBDonor |
| LYS 66 | B2.6 | THR 13 | - | VdWContact |
| LYS 66 | B2.6 | VAL 15 | - | Hydrophobic |
| LYS 66 | B2.6 | VAL 15 | - | VdWContact |
| VAL 68 | b2b3.3 | PHE 20 | - | Hydrophobic |
| VAL 68 | b2b3.3 | PHE 20 | - | VdWContact |
| SER 69 | b2b3.4 | VAL 15 | - | VdWContact |
| SER 69 | b2b3.4 | ASP 16 | - | HBAcceptor |
| SER 69 | b2b3.4 | ASP 16 | - | HBDonor |
| SER 69 | b2b3.4 | ASP 16 | - | VdWContact |
| SER 69 | b2b3.4 | LEU 19 | - | VdWContact |
| SER 69 | b2b3.4 | PHE 20 | - | VdWContact |
| LYS 70 | b2b3.11 | ASP 11 | - | Cationic |
| LYS 70 | b2b3.11 | ASP 11 | - | HBDonor |
| LYS 70 | b2b3.11 | ASP 11 | - | VdWContact |
| LYS 70 | b2b3.11 | THR 13 | - | HBDonor |
| LYS 70 | b2b3.11 | THR 13 | - | VdWContact |
| ARG 72 | B3.1 | LEU 19 | - | HBDonor |
| ARG 72 | B3.1 | LEU 19 | - | Hydrophobic |
| ARG 72 | B3.1 | LEU 19 | - | VdWContact |
| ARG 72 | B3.1 | PHE 20 | - | VdWContact |
| ARG 72 | B3.1 | GLU 21 | - | HBDonor |
| SER 73 | B3.2 | LEU 19 | - | VdWContact |
