Predicted complex interactions
CCL18_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 68
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | GLU 298 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm29 | GLU 298 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm29 | GLU 298 | 7.39x38 | VdWContact |
| GLN 2 | NTc.Cm28 | ALA 197 | 45.52x52 | VdWContact |
| GLN 2 | NTc.Cm28 | ARG 211 | 5.39x40 | HBAcceptor |
| GLN 2 | NTc.Cm28 | ARG 211 | 5.39x40 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 294 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm27 | LEU 294 | 7.35x34 | VdWContact |
| THR 5 | NTc.Cm25 | VAL 42 | 1.28x28 | VdWContact |
| THR 5 | NTc.Cm25 | LEU 49 | 1.35x35 | Hydrophobic |
| THR 5 | NTc.Cm25 | VAL 106 | 2.64x64 | Hydrophobic |
| ASN 6 | NTc.Cm24 | ASN 194 | - | HBDonor |
| ASN 6 | NTc.Cm24 | ASN 194 | - | VdWContact |
| LYS 7 | NTc.Cm23 | LYS 38 | 1.24x24 | Hydrophobic |
| LYS 7 | NTc.Cm23 | LYS 38 | 1.24x24 | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 291 | 7.32x31 | Cationic |
| GLU 8 | NTc.Cm22 | ARG 37 | - | VdWContact |
| GLU 8 | NTc.Cm22 | LYS 38 | 1.24x24 | HBAcceptor |
| GLU 8 | NTc.Cm22 | LYS 38 | 1.24x24 | VdWContact |
| LEU 9 | NTc.Cm21 | LEU 35 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ARG 37 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ARG 37 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 36 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 36 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 36 | - | VdWContact |
| CYS 10 | NTc.Cm20 | LYS 38 | 1.24x24 | Anionic |
| LEU 12 | NTc.Cm18 | MET 34 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 36 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | ASN 283 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 284 | 7.25x24 | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 284 | 7.25x24 | VdWContact |
| VAL 13 | NTc.Cm17 | MET 34 | - | Hydrophobic |
| VAL 13 | NTc.Cm17 | MET 34 | - | VdWContact |
| TYR 14 | NTc.Cm16 | MET 34 | - | VdWContact |
| THR 15 | NTc.Cm15 | MET 34 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 27 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | TYR 27 | - | VdWContact |
| ILE 19 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| ILE 19 | NTc.Cm11 | TYR 24 | - | VdWContact |
| PRO 20 | NTc.Cm10 | TYR 24 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 24 | - | VdWContact |
| PHE 23 | NTc.Cm7 | TYR 24 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TYR 25 | - | Hydrophobic |
| GLN 33 | cxb1.2 | HIS 196 | 45.51x51 | Hydrophobic |
| GLN 33 | cxb1.2 | HIS 196 | 45.51x51 | VdWContact |
| PRO 35 | cxb1.6 | LEU 276 | 6.61x61 | Hydrophobic |
| PRO 35 | cxb1.6 | ASP 277 | 6.62x62 | VdWContact |
| LYS 36 | cxb1.7 | GLN 279 | 6.64x64 | HBDonor |
| LYS 36 | cxb1.7 | GLN 279 | 6.64x64 | Hydrophobic |
| LYS 36 | cxb1.7 | GLN 279 | 6.64x64 | VdWContact |
| ILE 40 | cxb1.14 | LEU 35 | - | Hydrophobic |
| ILE 40 | cxb1.14 | LEU 35 | - | VdWContact |
| THR 43 | B1.1 | LEU 28 | - | Hydrophobic |
| ARG 45 | B1.3 | TYR 25 | - | CationPi |
| ARG 45 | B1.3 | TYR 25 | - | Hydrophobic |
| ARG 45 | B1.3 | TYR 25 | - | VdWContact |
| ARG 47 | B1.5 | TYR 25 | - | HBDonor |
| ARG 47 | B1.5 | TYR 25 | - | VdWContact |
| ARG 47 | B1.5 | ASP 29 | - | Cationic |
| ARG 47 | B1.5 | ASP 29 | - | VdWContact |
| GLN 48 | B1.6 | LEU 35 | - | Hydrophobic |
| GLN 48 | B1.6 | LEU 35 | - | VdWContact |
| ILE 49 | B1.7 | LEU 28 | - | Hydrophobic |
| ILE 49 | B1.7 | LEU 28 | - | VdWContact |
| ILE 49 | B1.7 | VAL 31 | - | Hydrophobic |
| CYS 50 | b1b2.4 | MET 34 | - | Hydrophobic |
| CYS 50 | b1b2.4 | MET 34 | - | VdWContact |
| CYS 50 | b1b2.4 | LEU 35 | - | VdWContact |
