Predicted complex interactions
CXCL8_HUMAN + CCR7
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR7 View partner entry
- Partner description
- UniProt: P32248; Gene: ccr7_human; Family: Chemokine
- Interactions detected
- 89
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LEU 5 | NTc.Cm29 | ARG 177 | 4.44x44 | VdWContact |
| LEU 5 | NTc.Cm29 | SER 179 | 4.46x46 | VdWContact |
| PRO 6 | NTc.Cm28 | ARG 177 | 4.44x44 | Hydrophobic |
| PRO 6 | NTc.Cm28 | ARG 177 | 4.44x44 | VdWContact |
| ARG 7 | NTc.Cm27 | SER 187 | 4.54x54 | HBAcceptor |
| ARG 7 | NTc.Cm27 | SER 187 | 4.54x54 | VdWContact |
| ARG 7 | NTc.Cm27 | THR 190 | 4.57x57 | HBDonor |
| ARG 7 | NTc.Cm27 | THR 190 | 4.57x57 | VdWContact |
| SER 8 | NTc.Cm26 | SER 187 | 4.54x54 | VdWContact |
| ALA 9 | NTc.Cm25 | PHE 109 | 2.55x55 | Hydrophobic |
| ALA 9 | NTc.Cm25 | SER 187 | 4.54x54 | VdWContact |
| ALA 9 | NTc.Cm25 | LEU 188 | 4.55x55 | Hydrophobic |
| ALA 9 | NTc.Cm25 | LEU 188 | 4.55x55 | VdWContact |
| LYS 10 | NTc.Cm24 | LYS 33 | - | HBAcceptor |
| LYS 10 | NTc.Cm24 | LYS 33 | - | VdWContact |
| LYS 10 | NTc.Cm24 | TYR 284 | 6.56x56 | HBDonor |
| LYS 10 | NTc.Cm24 | TYR 284 | 6.56x56 | Hydrophobic |
| LYS 10 | NTc.Cm24 | TYR 284 | 6.56x56 | VdWContact |
| LYS 10 | NTc.Cm24 | TYR 288 | 6.60x60 | CationPi |
| LYS 10 | NTc.Cm24 | TYR 288 | 6.60x60 | VdWContact |
| GLU 11 | NTc.Cm23 | LYS 33 | - | Anionic |
| GLU 11 | NTc.Cm23 | LYS 33 | - | HBAcceptor |
| GLU 11 | NTc.Cm23 | LYS 33 | - | Hydrophobic |
| GLU 11 | NTc.Cm23 | LYS 33 | - | VdWContact |
| GLU 11 | NTc.Cm23 | ARG 185 | 4.52x52 | Anionic |
| GLU 11 | NTc.Cm23 | ARG 185 | 4.52x52 | HBAcceptor |
| GLU 11 | NTc.Cm23 | ARG 185 | 4.52x52 | VdWContact |
| ARG 13 | NTc.Cm21 | LYS 26 | - | Hydrophobic |
| ARG 13 | NTc.Cm21 | LYS 26 | - | VdWContact |
| ARG 13 | NTc.Cm21 | GLN 262 | 6.34x34 | VdWContact |
| ARG 13 | NTc.Cm21 | SER 277 | 6.49x49 | HBDonor |
| ARG 13 | NTc.Cm21 | SER 277 | 6.49x49 | VdWContact |
| ARG 13 | NTc.Cm21 | LEU 280 | 6.52x52 | VdWContact |
| ARG 13 | NTc.Cm21 | ASN 281 | 6.53x53 | HBDonor |
| ARG 13 | NTc.Cm21 | ASN 281 | 6.53x53 | VdWContact |
| CYS 14 | NTc.Cm20 | LYS 26 | - | HBAcceptor |
| CYS 14 | NTc.Cm20 | LYS 26 | - | VdWContact |
| GLN 15 | NTc.Cm19 | LEU 23 | - | Hydrophobic |
| GLN 15 | NTc.Cm19 | LEU 23 | - | VdWContact |
| GLN 15 | NTc.Cm19 | CYS 24 | - | HBAcceptor |
| GLN 15 | NTc.Cm19 | CYS 24 | - | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 24 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 24 | - | VdWContact |
| ILE 17 | NTc.Cm17 | LYS 26 | - | VdWContact |
| ILE 17 | NTc.Cm17 | ILE 269 | 6.41x41 | VdWContact |
| ILE 17 | NTc.Cm17 | SER 272 | 6.44x44 | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 274 | 6.46x46 | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 274 | 6.46x46 | VdWContact |
| ILE 17 | NTc.Cm17 | SER 277 | 6.49x49 | VdWContact |
| LYS 18 | NTc.Cm16 | GLU 21 | - | Cationic |
| LYS 18 | NTc.Cm16 | GLU 21 | - | HBDonor |
| LYS 18 | NTc.Cm16 | GLU 21 | - | VdWContact |
| LYS 18 | NTc.Cm16 | ILE 269 | 6.41x41 | Hydrophobic |
| LYS 18 | NTc.Cm16 | ILE 269 | 6.41x41 | VdWContact |
| LYS 18 | NTc.Cm16 | THR 270 | 6.42x42 | VdWContact |
| TYR 20 | NTc.Cm14 | LEU 19 | - | VdWContact |
| TYR 20 | NTc.Cm14 | PHE 20 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | PHE 20 | - | PiStacking |
| TYR 20 | NTc.Cm14 | PHE 20 | - | VdWContact |
| TYR 20 | NTc.Cm14 | GLU 21 | - | VdWContact |
| PHE 24 | NTc.Cm10 | PHE 20 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | PHE 20 | - | VdWContact |
| HIS 25 | NTc.Cm9 | THR 5 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | TYR 8 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | TYR 8 | - | VdWContact |
| PHE 28 | NTc.Cm6 | VAL 15 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | VAL 15 | - | VdWContact |
| PHE 28 | NTc.Cm6 | TYR 17 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | TYR 17 | - | VdWContact |
| ILE 35 | CX.4 | SER 179 | 4.46x46 | VdWContact |
| GLY 38 | cxb1.2 | GLN 176 | 4.43x43 | VdWContact |
| PRO 39 | cxb1.5 | GLN 176 | 4.43x43 | VdWContact |
| ALA 42 | cxb1.8 | VAL 193 | 4.60x61 | Hydrophobic |
| ILE 47 | cxb1.16 | LEU 23 | - | Hydrophobic |
| ILE 47 | cxb1.16 | LEU 23 | - | VdWContact |
| LEU 50 | B1.3 | TYR 17 | - | Hydrophobic |
| LEU 50 | B1.3 | TYR 17 | - | VdWContact |
| LEU 50 | B1.3 | PHE 20 | - | Hydrophobic |
| ARG 54 | B1.7 | TYR 17 | - | HBDonor |
| ARG 54 | B1.7 | TYR 17 | - | VdWContact |
| GLU 55 | b1b2.4 | LEU 23 | - | HBAcceptor |
| GLU 55 | b1b2.4 | LEU 23 | - | Hydrophobic |
| GLU 55 | b1b2.4 | LEU 23 | - | VdWContact |
| LEU 56 | b1b2.6 | PHE 20 | - | Hydrophobic |
| LEU 56 | b1b2.6 | PHE 20 | - | VdWContact |
| CYS 57 | b1b2.7 | LEU 23 | - | VdWContact |
| LYS 71 | b2b3.2 | VAL 4 | - | VdWContact |
| LYS 71 | b2b3.2 | THR 5 | - | HBDonor |
| LYS 71 | b2b3.2 | THR 5 | - | VdWContact |
