Predicted complex interactions
CCL14_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL14_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 98
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 5 | NTc.Cm30 | GLN 98 | 23.49x49 | VdWContact |
| SER 7 | NTc.Cm28 | LEU 96 | 2.65x65 | VdWContact |
| ARG 8 | NTc.Cm27 | GLN 98 | 23.49x49 | VdWContact |
| ARG 8 | NTc.Cm27 | VAL 180 | - | Hydrophobic |
| ARG 8 | NTc.Cm27 | VAL 180 | - | VdWContact |
| GLY 9 | NTc.Cm26 | TYR 94 | 2.63x63 | VdWContact |
| GLY 9 | NTc.Cm26 | ASP 97 | 2.66x66 | VdWContact |
| PRO 10 | NTc.Cm25 | TYR 94 | 2.63x63 | Hydrophobic |
| PRO 10 | NTc.Cm25 | TYR 94 | 2.63x63 | VdWContact |
| PRO 10 | NTc.Cm25 | LEU 95 | 2.64x64 | VdWContact |
| TYR 11 | NTc.Cm24 | GLU 28 | - | Hydrophobic |
| TYR 11 | NTc.Cm24 | GLU 28 | - | VdWContact |
| TYR 11 | NTc.Cm24 | LYS 35 | 1.32x32 | HBAcceptor |
| TYR 11 | NTc.Cm24 | LYS 35 | 1.32x32 | VdWContact |
| TYR 11 | NTc.Cm24 | LEU 38 | 1.35x35 | Hydrophobic |
| TYR 11 | NTc.Cm24 | TYR 42 | 1.39x39 | HBAcceptor |
| TYR 11 | NTc.Cm24 | TYR 42 | 1.39x39 | VdWContact |
| TYR 11 | NTc.Cm24 | LEU 95 | 2.64x64 | Hydrophobic |
| TYR 11 | NTc.Cm24 | LEU 95 | 2.64x64 | VdWContact |
| TYR 11 | NTc.Cm24 | HIS 283 | 7.36x35 | Hydrophobic |
| TYR 11 | NTc.Cm24 | HIS 283 | 7.36x35 | VdWContact |
| TYR 11 | NTc.Cm24 | GLU 286 | 7.39x38 | HBDonor |
| TYR 11 | NTc.Cm24 | GLU 286 | 7.39x38 | VdWContact |
| HIS 12 | NTc.Cm23 | GLU 28 | - | VdWContact |
| HIS 12 | NTc.Cm23 | LYS 35 | 1.32x32 | HBAcceptor |
| HIS 12 | NTc.Cm23 | LYS 35 | 1.32x32 | PiCation |
| HIS 12 | NTc.Cm23 | LYS 35 | 1.32x32 | VdWContact |
| PRO 13 | NTc.Cm22 | ASP 26 | - | Hydrophobic |
| PRO 13 | NTc.Cm22 | ASP 26 | - | VdWContact |
| PRO 13 | NTc.Cm22 | GLU 28 | - | Hydrophobic |
| PRO 13 | NTc.Cm22 | GLU 28 | - | VdWContact |
| SER 14 | NTc.Cm21 | ALA 27 | - | HBAcceptor |
| SER 14 | NTc.Cm21 | ALA 27 | - | VdWContact |
| GLU 15 | NTc.Cm20 | PRO 24 | - | Hydrophobic |
| GLU 15 | NTc.Cm20 | PRO 24 | - | VdWContact |
| GLU 15 | NTc.Cm20 | CYS 25 | - | VdWContact |
| CYS 16 | NTc.Cm19 | CYS 25 | - | HBAcceptor |
| CYS 16 | NTc.Cm19 | CYS 25 | - | HBDonor |
| CYS 16 | NTc.Cm19 | CYS 25 | - | VdWContact |
| PHE 18 | NTc.Cm17 | CYS 25 | - | Hydrophobic |
| PHE 18 | NTc.Cm17 | CYS 25 | - | VdWContact |
| PHE 18 | NTc.Cm17 | HIS 264 | 6.61x61 | Hydrophobic |
| PHE 18 | NTc.Cm17 | HIS 264 | 6.61x61 | VdWContact |
| PHE 18 | NTc.Cm17 | CYS 272 | 7.25x24 | Hydrophobic |
| PHE 18 | NTc.Cm17 | CYS 272 | 7.25x24 | VdWContact |
| PHE 18 | NTc.Cm17 | SER 275 | 7.28x27 | VdWContact |
| THR 19 | NTc.Cm16 | PHE 21 | - | HBDonor |
| THR 19 | NTc.Cm16 | PHE 21 | - | VdWContact |
| THR 19 | NTc.Cm16 | SER 22 | - | VdWContact |
| THR 22 | NTc.Cm13 | ASP 19 | - | HBDonor |
| THR 22 | NTc.Cm13 | ASP 19 | - | VdWContact |
| TYR 23 | NTc.Cm12 | PRO 18 | - | Hydrophobic |
| TYR 23 | NTc.Cm12 | PRO 18 | - | VdWContact |
| TYR 23 | NTc.Cm12 | ASP 19 | - | HBAcceptor |
| TYR 23 | NTc.Cm12 | ASP 19 | - | Hydrophobic |
| TYR 23 | NTc.Cm12 | ASP 19 | - | VdWContact |
| ARG 29 | NTc.Cm6 | ASP 14 | - | Cationic |
| ARG 29 | NTc.Cm6 | ASP 14 | - | HBDonor |
| ARG 29 | NTc.Cm6 | ASP 14 | - | VdWContact |
| ARG 29 | NTc.Cm6 | TYR 16 | - | HBDonor |
| ARG 29 | NTc.Cm6 | TYR 16 | - | VdWContact |
| ARG 29 | NTc.Cm6 | TYR 17 | - | CationPi |
| ARG 29 | NTc.Cm6 | TYR 17 | - | Hydrophobic |
| ASN 37 | cxb1.1 | GLU 177 | - | VdWContact |
| ASN 37 | cxb1.1 | ASP 178 | - | HBDonor |
| ASN 37 | cxb1.1 | ASP 178 | - | VdWContact |
| ASN 37 | cxb1.1 | GLN 182 | - | HBDonor |
| ASN 37 | cxb1.1 | GLN 182 | - | VdWContact |
| SER 38 | cxb1.2 | GLU 177 | - | HBDonor |
| SER 38 | cxb1.2 | GLU 177 | - | VdWContact |
| SER 38 | cxb1.2 | THR 191 | 5.31x32 | HBAcceptor |
| SER 38 | cxb1.2 | THR 191 | 5.31x32 | VdWContact |
| GLN 39 | cxb1.5 | GLN 182 | - | HBDonor |
| GLN 39 | cxb1.5 | GLN 182 | - | VdWContact |
| GLN 39 | cxb1.5 | TYR 184 | 45.51x51 | Hydrophobic |
| GLN 39 | cxb1.5 | THR 191 | 5.31x32 | Hydrophobic |
| GLN 39 | cxb1.5 | THR 191 | 5.31x32 | VdWContact |
| SER 41 | cxb1.7 | HIS 267 | 6.64x64 | VdWContact |
| LYS 42 | cxb1.8 | HIS 267 | 6.64x64 | Hydrophobic |
| LYS 42 | cxb1.8 | HIS 267 | 6.64x64 | VdWContact |
| LYS 42 | cxb1.8 | ASP 270 | - | Cationic |
| LYS 42 | cxb1.8 | ASP 270 | - | HBDonor |
| LYS 42 | cxb1.8 | ASP 270 | - | VdWContact |
| VAL 46 | cxb1.15 | PRO 24 | - | Hydrophobic |
| THR 49 | B1.2 | TYR 17 | - | Hydrophobic |
| THR 49 | B1.2 | TYR 17 | - | VdWContact |
| ARG 51 | B1.4 | ASP 14 | - | HBDonor |
| ARG 51 | B1.4 | ASP 14 | - | VdWContact |
| ARG 51 | B1.4 | TYR 15 | - | CationPi |
| ARG 51 | B1.4 | TYR 15 | - | VdWContact |
| ARG 51 | B1.4 | TYR 17 | - | Hydrophobic |
| ARG 51 | B1.4 | TYR 17 | - | VdWContact |
| HIS 53 | B1.6 | TYR 17 | - | Hydrophobic |
| HIS 53 | B1.6 | TYR 17 | - | VdWContact |
| VAL 55 | b1b2.4 | SER 22 | - | VdWContact |
| CYS 56 | b1b2.6 | SER 22 | - | HBDonor |
| CYS 56 | b1b2.6 | SER 22 | - | VdWContact |
| CYS 56 | b1b2.6 | PRO 24 | - | VdWContact |
