Predicted complex interactions
CCL15_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL15_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 112
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 18 | NTc.Cm35 | THR 32 | 1.29x29 | HBAcceptor |
| GLU 18 | NTc.Cm35 | THR 32 | 1.29x29 | VdWContact |
| PRO 20 | NTc.Cm33 | ASP 26 | - | VdWContact |
| VAL 21 | NTc.Cm32 | LYS 35 | 1.32x32 | Hydrophobic |
| VAL 21 | NTc.Cm32 | LYS 35 | 1.32x32 | VdWContact |
| VAL 22 | NTc.Cm31 | GLU 28 | - | VdWContact |
| VAL 22 | NTc.Cm31 | LYS 35 | 1.32x32 | HBAcceptor |
| VAL 22 | NTc.Cm31 | LYS 35 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm30 | GLU 28 | - | HBDonor |
| LEU 23 | NTc.Cm30 | GLU 28 | - | Hydrophobic |
| LEU 23 | NTc.Cm30 | GLU 28 | - | VdWContact |
| LEU 23 | NTc.Cm30 | ILE 30 | - | Hydrophobic |
| LEU 23 | NTc.Cm30 | ILE 30 | - | VdWContact |
| LEU 23 | NTc.Cm30 | LYS 35 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm30 | LYS 35 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm30 | LEU 38 | 1.35x35 | Hydrophobic |
| LEU 23 | NTc.Cm30 | LEU 95 | 2.64x64 | Hydrophobic |
| LEU 23 | NTc.Cm30 | LEU 95 | 2.64x64 | VdWContact |
| LEU 23 | NTc.Cm30 | HIS 283 | 7.36x35 | Hydrophobic |
| LEU 23 | NTc.Cm30 | HIS 283 | 7.36x35 | VdWContact |
| ASN 24 | NTc.Cm29 | TYR 94 | 2.63x63 | Hydrophobic |
| ASN 24 | NTc.Cm29 | TYR 94 | 2.63x63 | VdWContact |
| ASN 24 | NTc.Cm29 | ASP 97 | 2.66x66 | HBDonor |
| ASN 24 | NTc.Cm29 | ASP 97 | 2.66x66 | VdWContact |
| ASN 24 | NTc.Cm29 | GLN 98 | 23.49x49 | VdWContact |
| ASN 24 | NTc.Cm29 | VAL 180 | - | VdWContact |
| SER 25 | NTc.Cm28 | TYR 94 | 2.63x63 | VdWContact |
| SER 25 | NTc.Cm28 | HIS 283 | 7.36x35 | VdWContact |
| PHE 26 | NTc.Cm27 | GLN 91 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm27 | GLN 91 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm27 | TRP 99 | 23.50x50 | Hydrophobic |
| PHE 26 | NTc.Cm27 | VAL 109 | 3.28x28 | Hydrophobic |
| PHE 26 | NTc.Cm27 | VAL 109 | 3.28x28 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 113 | 3.32x32 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 172 | 4.64x65 | HBAcceptor |
| PHE 26 | NTc.Cm27 | TYR 172 | 4.64x65 | Hydrophobic |
| PHE 26 | NTc.Cm27 | TYR 172 | 4.64x65 | VdWContact |
| PHE 26 | NTc.Cm27 | CYS 183 | 45.50x50 | VdWContact |
| PHE 26 | NTc.Cm27 | TYR 184 | 45.51x51 | VdWContact |
| HIS 27 | NTc.Cm26 | MET 202 | 5.42x43 | Hydrophobic |
| HIS 27 | NTc.Cm26 | PHE 254 | 6.51x51 | Hydrophobic |
| HIS 27 | NTc.Cm26 | PHE 254 | 6.51x51 | VdWContact |
| HIS 27 | NTc.Cm26 | LEU 258 | 6.55x55 | Hydrophobic |
| HIS 27 | NTc.Cm26 | LEU 258 | 6.55x55 | VdWContact |
| HIS 27 | NTc.Cm26 | THR 282 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm26 | GLU 286 | 7.39x38 | VdWContact |
| PHE 28 | NTc.Cm25 | GLU 177 | - | Hydrophobic |
| PHE 28 | NTc.Cm25 | GLN 182 | - | VdWContact |
| PHE 28 | NTc.Cm25 | TYR 184 | 45.51x51 | Hydrophobic |
| PHE 28 | NTc.Cm25 | PHE 186 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | ALA 27 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | ALA 27 | - | VdWContact |
| ALA 29 | NTc.Cm24 | GLU 28 | - | Hydrophobic |
| ALA 29 | NTc.Cm24 | THR 279 | 7.32x31 | Hydrophobic |
| ALA 29 | NTc.Cm24 | THR 279 | 7.32x31 | VdWContact |
| ALA 30 | NTc.Cm23 | ALA 27 | - | VdWContact |
| ASP 31 | NTc.Cm22 | CYS 25 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ASP 26 | - | VdWContact |
| ASP 31 | NTc.Cm22 | ALA 27 | - | HBAcceptor |
| ASP 31 | NTc.Cm22 | ALA 27 | - | VdWContact |
| CYS 32 | NTc.Cm21 | CYS 25 | - | HBAcceptor |
| CYS 32 | NTc.Cm21 | CYS 25 | - | HBDonor |
| CYS 32 | NTc.Cm21 | CYS 25 | - | VdWContact |
| THR 34 | NTc.Cm19 | CYS 25 | - | Hydrophobic |
| THR 34 | NTc.Cm19 | CYS 272 | 7.25x24 | Hydrophobic |
| SER 35 | NTc.Cm18 | PHE 21 | - | HBDonor |
| SER 35 | NTc.Cm18 | PHE 21 | - | VdWContact |
| ILE 37 | NTc.Cm16 | TYR 16 | - | VdWContact |
| PRO 42 | NTc.Cm11 | TYR 16 | - | Hydrophobic |
| PRO 42 | NTc.Cm11 | TYR 16 | - | VdWContact |
| LEU 45 | NTc.Cm8 | TYR 16 | - | Hydrophobic |
| LEU 45 | NTc.Cm8 | TYR 16 | - | VdWContact |
| MET 46 | NTc.Cm7 | TYR 16 | - | Hydrophobic |
| PHE 50 | NTc.Cm3 | ASP 178 | - | VdWContact |
| SER 53 | CX.1 | GLU 177 | - | HBDonor |
| SER 53 | CX.1 | GLU 177 | - | VdWContact |
| SER 54 | CX.5 | GLN 189 | - | VdWContact |
| SER 54 | CX.5 | THR 191 | 5.31x32 | HBAcceptor |
| SER 54 | CX.5 | THR 191 | 5.31x32 | VdWContact |
| SER 54 | CX.5 | LEU 192 | 5.32x33 | HBAcceptor |
| SER 54 | CX.5 | LEU 192 | 5.32x33 | VdWContact |
| GLU 55 | cxb1.1 | THR 191 | 5.31x32 | Hydrophobic |
| GLU 55 | cxb1.1 | THR 191 | 5.31x32 | VdWContact |
| GLU 55 | cxb1.1 | LEU 192 | 5.32x33 | VdWContact |
| GLU 55 | cxb1.1 | LYS 195 | 5.35x36 | Anionic |
| GLU 55 | cxb1.1 | LYS 195 | 5.35x36 | HBAcceptor |
| GLU 55 | cxb1.1 | LYS 195 | 5.35x36 | Hydrophobic |
| GLU 55 | cxb1.1 | LYS 195 | 5.35x36 | VdWContact |
| SER 57 | cxb1.5 | HIS 267 | 6.64x64 | VdWContact |
| LYS 58 | cxb1.6 | HIS 267 | 6.64x64 | Hydrophobic |
| ILE 62 | cxb1.11 | PRO 24 | - | Hydrophobic |
| ILE 62 | cxb1.11 | PRO 24 | - | VdWContact |
| THR 65 | cxb1.16 | PRO 18 | - | Hydrophobic |
| LYS 67 | B1.2 | ASP 14 | - | HBDonor |
| LYS 67 | B1.2 | ASP 14 | - | VdWContact |
| LYS 67 | B1.2 | TYR 15 | - | CationPi |
| LYS 67 | B1.2 | TYR 15 | - | VdWContact |
| ARG 69 | B1.4 | TYR 17 | - | VdWContact |
| ARG 69 | B1.4 | PRO 18 | - | Hydrophobic |
| ARG 69 | B1.4 | PRO 18 | - | VdWContact |
| GLN 70 | B1.5 | PRO 24 | - | Hydrophobic |
| GLN 70 | B1.5 | PRO 24 | - | VdWContact |
| VAL 71 | B1.6 | TYR 16 | - | Hydrophobic |
| VAL 71 | B1.6 | PRO 18 | - | Hydrophobic |
| VAL 71 | B1.6 | PRO 18 | - | VdWContact |
| CYS 72 | B1.7 | SER 22 | - | HBDonor |
| CYS 72 | B1.7 | SER 22 | - | VdWContact |
| CYS 72 | B1.7 | PRO 24 | - | VdWContact |
| SER 91 | B3.1 | GLY 179 | - | VdWContact |
| ILE 92 | B3.2 | ASP 178 | - | HBDonor |
| ILE 92 | B3.2 | ASP 178 | - | Hydrophobic |
| ILE 92 | B3.2 | ASP 178 | - | VdWContact |
