Predicted complex interactions
CCL19_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 86
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | TRP 102 | 2.60x60 | CationPi |
| GLY 1 | NTc.Cm28 | GLU 298 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 298 | 7.39x38 | VdWContact |
| THR 2 | NTc.Cm27 | ARG 211 | 5.39x40 | HBAcceptor |
| THR 2 | NTc.Cm27 | ARG 211 | 5.39x40 | VdWContact |
| ASN 3 | NTc.Cm26 | LEU 49 | 1.35x35 | VdWContact |
| ASN 3 | NTc.Cm26 | GLN 295 | 7.36x35 | HBAcceptor |
| ASN 3 | NTc.Cm26 | GLN 295 | 7.36x35 | VdWContact |
| ASP 4 | NTc.Cm25 | LYS 207 | 5.35x36 | Anionic |
| ALA 5 | NTc.Cm24 | LYS 38 | 1.24x24 | Hydrophobic |
| ALA 5 | NTc.Cm24 | VAL 41 | 1.27x27 | Hydrophobic |
| ALA 5 | NTc.Cm24 | VAL 42 | 1.28x28 | Hydrophobic |
| ALA 5 | NTc.Cm24 | ASP 291 | 7.32x31 | Hydrophobic |
| GLU 6 | NTc.Cm23 | LYS 38 | 1.24x24 | VdWContact |
| ASP 7 | NTc.Cm22 | LEU 35 | - | Hydrophobic |
| ASP 7 | NTc.Cm22 | CYS 36 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ARG 37 | - | VdWContact |
| ASP 7 | NTc.Cm22 | LYS 38 | 1.24x24 | HBAcceptor |
| ASP 7 | NTc.Cm22 | LYS 38 | 1.24x24 | VdWContact |
| CYS 8 | NTc.Cm21 | LEU 35 | - | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 36 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 36 | - | HBDonor |
| CYS 8 | NTc.Cm21 | CYS 36 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 36 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 284 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 284 | 7.25x24 | VdWContact |
| SER 11 | NTc.Cm18 | ALA 32 | - | HBDonor |
| SER 11 | NTc.Cm18 | ALA 32 | - | VdWContact |
| SER 11 | NTc.Cm18 | PHE 33 | - | VdWContact |
| VAL 12 | NTc.Cm17 | PHE 33 | - | VdWContact |
| THR 13 | NTc.Cm16 | PHE 33 | - | VdWContact |
| LYS 15 | NTc.Cm14 | TYR 27 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | TYR 27 | - | VdWContact |
| PRO 16 | NTc.Cm13 | TYR 24 | - | VdWContact |
| ILE 17 | NTc.Cm12 | TYR 24 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| PRO 18 | NTc.Cm11 | TYR 24 | - | VdWContact |
| TYR 20 | NTc.Cm9 | SER 17 | - | HBDonor |
| TYR 20 | NTc.Cm9 | SER 17 | - | VdWContact |
| TYR 20 | NTc.Cm9 | SER 20 | - | HBAcceptor |
| TYR 20 | NTc.Cm9 | SER 20 | - | VdWContact |
| TYR 20 | NTc.Cm9 | SER 21 | - | HBDonor |
| TYR 20 | NTc.Cm9 | SER 21 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 24 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 25 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 25 | - | VdWContact |
| ILE 21 | NTc.Cm8 | LEU 28 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | LEU 35 | - | Hydrophobic |
| LEU 28 | NTc.Cm1 | LEU 35 | - | VdWContact |
| ILE 30 | CX.5 | GLY 200 | - | VdWContact |
| ILE 30 | CX.5 | GLY 201 | - | VdWContact |
| LYS 31 | cxb1.1 | HIS 186 | - | Hydrophobic |
| LYS 31 | cxb1.1 | HIS 196 | 45.51x51 | HBAcceptor |
| LYS 31 | cxb1.1 | HIS 196 | 45.51x51 | VdWContact |
| LYS 31 | cxb1.1 | ASP 198 | - | VdWContact |
| ASP 32 | cxb1.2 | ASN 188 | - | HBAcceptor |
| ASP 32 | cxb1.2 | ASN 188 | - | VdWContact |
| ARG 35 | cxb1.8 | HIS 273 | 6.58x58 | HBDonor |
| ARG 35 | cxb1.8 | LEU 276 | 6.61x61 | HBDonor |
| ARG 35 | cxb1.8 | LEU 276 | 6.61x61 | VdWContact |
| ARG 35 | cxb1.8 | ASP 277 | 6.62x62 | Cationic |
| ARG 35 | cxb1.8 | ASP 277 | 6.62x62 | HBDonor |
| ARG 35 | cxb1.8 | ASP 277 | 6.62x62 | VdWContact |
| VAL 36 | cxb1.9 | GLN 279 | 6.64x64 | VdWContact |
| VAL 40 | cxb1.15 | LEU 35 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 25 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 25 | - | VdWContact |
| ARG 45 | B1.4 | PHE 22 | - | VdWContact |
| ARG 45 | B1.4 | TYR 25 | - | CationPi |
| ARG 45 | B1.4 | TYR 25 | - | Hydrophobic |
| ARG 47 | B1.6 | TYR 25 | - | VdWContact |
| ARG 47 | B1.6 | ASP 29 | - | Cationic |
| ARG 47 | B1.6 | ASP 29 | - | HBDonor |
| ARG 47 | B1.6 | ASP 29 | - | VdWContact |
| GLN 48 | B1.7 | MET 34 | - | VdWContact |
| GLN 48 | B1.7 | LEU 35 | - | HBAcceptor |
| GLN 48 | B1.7 | LEU 35 | - | Hydrophobic |
| GLN 48 | B1.7 | LEU 35 | - | VdWContact |
| GLN 48 | B1.7 | ARG 37 | - | HBAcceptor |
| GLN 48 | B1.7 | ARG 37 | - | VdWContact |
| LEU 49 | b1b2.4 | LEU 28 | - | Hydrophobic |
| LEU 49 | b1b2.4 | LEU 28 | - | VdWContact |
| LEU 49 | b1b2.4 | MET 34 | - | Hydrophobic |
| CYS 50 | b1b2.6 | PHE 33 | - | HBDonor |
| CYS 50 | b1b2.6 | PHE 33 | - | VdWContact |
| CYS 50 | b1b2.6 | LEU 35 | - | VdWContact |
