Predicted complex interactions
CCL16_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL16_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 100
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm36 | TYR 94 | 2.63x63 | HBAcceptor |
| GLN 1 | NTc.Cm36 | VAL 180 | - | Hydrophobic |
| GLN 1 | NTc.Cm36 | VAL 180 | - | VdWContact |
| GLN 1 | NTc.Cm36 | GLN 182 | - | VdWContact |
| PRO 2 | NTc.Cm35 | TYR 94 | 2.63x63 | Hydrophobic |
| PRO 2 | NTc.Cm35 | TYR 94 | 2.63x63 | VdWContact |
| LYS 3 | NTc.Cm34 | CYS 183 | 45.50x50 | VdWContact |
| LYS 3 | NTc.Cm34 | TYR 184 | 45.51x51 | Hydrophobic |
| LYS 3 | NTc.Cm34 | TYR 184 | 45.51x51 | VdWContact |
| VAL 4 | NTc.Cm33 | GLN 91 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm33 | GLN 91 | 2.60x60 | VdWContact |
| VAL 4 | NTc.Cm33 | TYR 94 | 2.63x63 | Hydrophobic |
| VAL 4 | NTc.Cm33 | TYR 94 | 2.63x63 | VdWContact |
| VAL 4 | NTc.Cm33 | TYR 172 | 4.64x65 | VdWContact |
| PRO 5 | NTc.Cm32 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 113 | 3.32x32 | VdWContact |
| PRO 5 | NTc.Cm32 | TYR 114 | 3.33x33 | Hydrophobic |
| PRO 5 | NTc.Cm32 | TYR 114 | 3.33x33 | VdWContact |
| PRO 5 | NTc.Cm32 | TYR 172 | 4.64x65 | VdWContact |
| GLU 6 | NTc.Cm31 | LYS 195 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm31 | LYS 195 | 5.35x36 | HBAcceptor |
| GLU 6 | NTc.Cm31 | LYS 195 | 5.35x36 | Hydrophobic |
| GLU 6 | NTc.Cm31 | LYS 195 | 5.35x36 | VdWContact |
| TRP 7 | NTc.Cm30 | TYR 42 | 1.39x39 | Hydrophobic |
| TRP 7 | NTc.Cm30 | TYR 42 | 1.39x39 | VdWContact |
| TRP 7 | NTc.Cm30 | GLN 91 | 2.60x60 | Hydrophobic |
| TRP 7 | NTc.Cm30 | GLN 91 | 2.60x60 | VdWContact |
| TRP 7 | NTc.Cm30 | TYR 113 | 3.32x32 | Hydrophobic |
| TRP 7 | NTc.Cm30 | THR 282 | 7.35x34 | Hydrophobic |
| TRP 7 | NTc.Cm30 | HIS 283 | 7.36x35 | Hydrophobic |
| TRP 7 | NTc.Cm30 | HIS 283 | 7.36x35 | VdWContact |
| TRP 7 | NTc.Cm30 | GLU 286 | 7.39x38 | VdWContact |
| TRP 7 | NTc.Cm30 | PHE 290 | 7.43x42 | Hydrophobic |
| TRP 7 | NTc.Cm30 | PHE 290 | 7.43x42 | VdWContact |
| VAL 8 | NTc.Cm29 | LEU 95 | 2.64x64 | Hydrophobic |
| VAL 8 | NTc.Cm29 | LEU 95 | 2.64x64 | VdWContact |
| VAL 8 | NTc.Cm29 | HIS 283 | 7.36x35 | Hydrophobic |
| VAL 8 | NTc.Cm29 | HIS 283 | 7.36x35 | VdWContact |
| ASN 9 | NTc.Cm28 | GLU 28 | - | VdWContact |
| ASN 9 | NTc.Cm28 | LYS 35 | 1.32x32 | VdWContact |
| ASN 9 | NTc.Cm28 | LEU 95 | 2.64x64 | HBDonor |
| ASN 9 | NTc.Cm28 | LEU 95 | 2.64x64 | VdWContact |
| THR 10 | NTc.Cm27 | GLU 177 | - | VdWContact |
| THR 10 | NTc.Cm27 | GLN 182 | - | HBDonor |
| THR 10 | NTc.Cm27 | GLN 182 | - | VdWContact |
| PRO 11 | NTc.Cm26 | GLU 28 | - | Hydrophobic |
| PRO 11 | NTc.Cm26 | GLU 28 | - | VdWContact |
| THR 13 | NTc.Cm24 | PRO 24 | - | Hydrophobic |
| THR 13 | NTc.Cm24 | PRO 24 | - | VdWContact |
| THR 13 | NTc.Cm24 | ASP 26 | - | HBDonor |
| THR 13 | NTc.Cm24 | ASP 26 | - | VdWContact |
| CYS 14 | NTc.Cm23 | CYS 25 | - | HBAcceptor |
| CYS 14 | NTc.Cm23 | CYS 25 | - | HBDonor |
| CYS 14 | NTc.Cm23 | CYS 25 | - | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 25 | - | Hydrophobic |
| LEU 16 | NTc.Cm21 | HIS 264 | 6.61x61 | Hydrophobic |
| LEU 16 | NTc.Cm21 | GLY 271 | 7.24x23 | VdWContact |
| LEU 16 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| LEU 16 | NTc.Cm21 | CYS 272 | 7.25x24 | VdWContact |
| TYR 19 | NTc.Cm18 | PRO 18 | - | Hydrophobic |
| TYR 19 | NTc.Cm18 | PRO 18 | - | VdWContact |
| LEU 23 | NTc.Cm14 | PRO 18 | - | Hydrophobic |
| PRO 24 | NTc.Cm13 | TYR 16 | - | Hydrophobic |
| ARG 26 | NTc.Cm11 | THR 10 | - | HBDonor |
| ARG 26 | NTc.Cm11 | THR 10 | - | VdWContact |
| LEU 27 | NTc.Cm10 | VAL 12 | - | Hydrophobic |
| LEU 27 | NTc.Cm10 | VAL 12 | - | VdWContact |
| LEU 27 | NTc.Cm10 | TYR 17 | - | Hydrophobic |
| ASN 36 | NTc.Cm1 | GLU 177 | - | HBDonor |
| ASN 36 | NTc.Cm1 | GLU 177 | - | VdWContact |
| ASN 36 | NTc.Cm1 | PHE 186 | - | Hydrophobic |
| ASN 36 | NTc.Cm1 | PHE 186 | - | VdWContact |
| HIS 38 | CX.5 | LEU 192 | 5.32x33 | Hydrophobic |
| HIS 38 | CX.5 | LEU 192 | 5.32x33 | VdWContact |
| HIS 38 | CX.5 | SER 265 | 6.62x62 | VdWContact |
| HIS 38 | CX.5 | HIS 267 | 6.64x64 | Hydrophobic |
| HIS 38 | CX.5 | HIS 267 | 6.64x64 | VdWContact |
| ILE 43 | cxb1.7 | PRO 24 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 17 | - | Hydrophobic |
| THR 46 | cxb1.11 | TYR 17 | - | VdWContact |
| ARG 48 | cxb1.15 | ASP 14 | - | Cationic |
| ARG 48 | cxb1.15 | ASP 14 | - | HBDonor |
| ARG 48 | cxb1.15 | ASP 14 | - | VdWContact |
| ARG 48 | cxb1.15 | TYR 17 | - | Hydrophobic |
| ARG 48 | cxb1.15 | TYR 17 | - | VdWContact |
| ARG 50 | B1.1 | ASP 14 | - | Cationic |
| ARG 50 | B1.1 | TYR 17 | - | VdWContact |
| GLU 51 | B1.2 | SER 23 | - | VdWContact |
| GLU 51 | B1.2 | PRO 24 | - | Hydrophobic |
| VAL 52 | B1.3 | PRO 18 | - | Hydrophobic |
| VAL 52 | B1.3 | PRO 18 | - | VdWContact |
| VAL 52 | B1.3 | SER 22 | - | VdWContact |
| CYS 53 | B1.4 | SER 22 | - | HBDonor |
| CYS 53 | B1.4 | SER 22 | - | VdWContact |
| CYS 53 | B1.4 | PRO 24 | - | VdWContact |
| THR 75 | B3.2 | ASP 178 | - | Hydrophobic |
| THR 75 | B3.2 | ASP 178 | - | VdWContact |
| ARG 76 | B3.3 | ASP 26 | - | Cationic |
| ARG 76 | B3.3 | ASP 26 | - | HBDonor |
| ARG 76 | B3.3 | ASP 26 | - | VdWContact |
