Predicted complex interactions
CCL18_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL18_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 83
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm29 | TYR 113 | 3.32x32 | HBDonor |
| ALA 1 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| ALA 1 | NTc.Cm29 | PHE 254 | 6.51x51 | Hydrophobic |
| ALA 1 | NTc.Cm29 | LEU 258 | 6.55x55 | Hydrophobic |
| ALA 1 | NTc.Cm29 | THR 282 | 7.35x34 | Hydrophobic |
| ALA 1 | NTc.Cm29 | GLU 286 | 7.39x38 | Cationic |
| ALA 1 | NTc.Cm29 | GLU 286 | 7.39x38 | HBDonor |
| ALA 1 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| GLN 2 | NTc.Cm28 | SER 110 | 3.29x29 | VdWContact |
| GLN 2 | NTc.Cm28 | TYR 172 | 4.64x65 | Hydrophobic |
| GLN 2 | NTc.Cm28 | TYR 172 | 4.64x65 | VdWContact |
| GLN 2 | NTc.Cm28 | CYS 183 | 45.50x50 | VdWContact |
| GLN 2 | NTc.Cm28 | TYR 184 | 45.51x51 | Hydrophobic |
| GLN 2 | NTc.Cm28 | TYR 184 | 45.51x51 | VdWContact |
| VAL 3 | NTc.Cm27 | THR 282 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm27 | HIS 283 | 7.36x35 | Hydrophobic |
| VAL 3 | NTc.Cm27 | HIS 283 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm26 | TYR 94 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm25 | GLU 28 | - | VdWContact |
| THR 5 | NTc.Cm25 | LYS 35 | 1.32x32 | HBAcceptor |
| THR 5 | NTc.Cm25 | LYS 35 | 1.32x32 | VdWContact |
| THR 5 | NTc.Cm25 | LEU 95 | 2.64x64 | Hydrophobic |
| THR 5 | NTc.Cm25 | LEU 95 | 2.64x64 | VdWContact |
| THR 5 | NTc.Cm25 | HIS 283 | 7.36x35 | Hydrophobic |
| THR 5 | NTc.Cm25 | HIS 283 | 7.36x35 | VdWContact |
| ASN 6 | NTc.Cm24 | VAL 180 | - | VdWContact |
| ASN 6 | NTc.Cm24 | GLN 182 | - | VdWContact |
| LYS 7 | NTc.Cm23 | ASP 26 | - | Cationic |
| GLU 8 | NTc.Cm22 | ALA 27 | - | HBAcceptor |
| GLU 8 | NTc.Cm22 | ALA 27 | - | Hydrophobic |
| GLU 8 | NTc.Cm22 | ALA 27 | - | VdWContact |
| LEU 9 | NTc.Cm21 | PRO 24 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 25 | - | VdWContact |
| LEU 9 | NTc.Cm21 | ASP 26 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | ASP 26 | - | VdWContact |
| CYS 10 | NTc.Cm20 | CYS 25 | - | HBAcceptor |
| CYS 10 | NTc.Cm20 | CYS 25 | - | HBDonor |
| CYS 10 | NTc.Cm20 | CYS 25 | - | VdWContact |
| LEU 12 | NTc.Cm18 | CYS 25 | - | Hydrophobic |
| LEU 12 | NTc.Cm18 | CYS 272 | 7.25x24 | Hydrophobic |
| VAL 13 | NTc.Cm17 | PHE 21 | - | VdWContact |
| TRP 17 | NTc.Cm13 | TYR 16 | - | HBDonor |
| TRP 17 | NTc.Cm13 | TYR 16 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | TYR 16 | - | VdWContact |
| TRP 17 | NTc.Cm13 | PRO 18 | - | Hydrophobic |
| TRP 17 | NTc.Cm13 | PRO 18 | - | VdWContact |
| ILE 19 | NTc.Cm11 | TYR 16 | - | VdWContact |
| ILE 19 | NTc.Cm11 | PRO 18 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 16 | - | Hydrophobic |
| PRO 20 | NTc.Cm10 | TYR 16 | - | VdWContact |
| PHE 23 | NTc.Cm7 | TYR 16 | - | Hydrophobic |
| PHE 23 | NTc.Cm7 | TYR 17 | - | Hydrophobic |
| PRO 32 | cxb1.1 | GLU 177 | - | VdWContact |
| PRO 32 | cxb1.1 | THR 191 | 5.31x32 | VdWContact |
| GLN 33 | cxb1.2 | TYR 184 | 45.51x51 | Hydrophobic |
| GLN 33 | cxb1.2 | TYR 184 | 45.51x51 | VdWContact |
| GLN 33 | cxb1.2 | THR 191 | 5.31x32 | Hydrophobic |
| PRO 35 | cxb1.6 | HIS 264 | 6.61x61 | Hydrophobic |
| PRO 35 | cxb1.6 | HIS 267 | 6.64x64 | Hydrophobic |
| PRO 35 | cxb1.6 | HIS 267 | 6.64x64 | VdWContact |
| LYS 36 | cxb1.7 | HIS 267 | 6.64x64 | Hydrophobic |
| LYS 36 | cxb1.7 | HIS 267 | 6.64x64 | VdWContact |
| ILE 40 | cxb1.14 | PRO 24 | - | Hydrophobic |
| THR 43 | B1.1 | TYR 17 | - | Hydrophobic |
| THR 43 | B1.1 | TYR 17 | - | VdWContact |
| ARG 45 | B1.3 | THR 13 | - | HBDonor |
| ARG 45 | B1.3 | THR 13 | - | VdWContact |
| ARG 45 | B1.3 | ASP 14 | - | Cationic |
| ARG 45 | B1.3 | ASP 14 | - | HBDonor |
| ARG 45 | B1.3 | ASP 14 | - | VdWContact |
| ARG 45 | B1.3 | TYR 17 | - | Hydrophobic |
| ARG 45 | B1.3 | TYR 17 | - | VdWContact |
| ARG 47 | B1.5 | ASP 14 | - | Cationic |
| ARG 47 | B1.5 | ASP 14 | - | HBDonor |
| ARG 47 | B1.5 | ASP 14 | - | VdWContact |
| ARG 47 | B1.5 | TYR 17 | - | VdWContact |
| GLN 48 | B1.6 | PRO 24 | - | Hydrophobic |
| ILE 49 | B1.7 | TYR 17 | - | Hydrophobic |
| ILE 49 | B1.7 | PRO 18 | - | VdWContact |
| ILE 49 | B1.7 | SER 22 | - | VdWContact |
| CYS 50 | b1b2.4 | SER 22 | - | HBDonor |
| CYS 50 | b1b2.4 | SER 22 | - | VdWContact |
| CYS 50 | b1b2.4 | PRO 24 | - | VdWContact |
