Predicted complex interactions
CCL19_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL19_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 70
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm28 | GLU 286 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm28 | GLU 286 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm28 | GLU 286 | 7.39x38 | VdWContact |
| THR 2 | NTc.Cm27 | TYR 94 | 2.63x63 | Hydrophobic |
| THR 2 | NTc.Cm27 | TYR 94 | 2.63x63 | VdWContact |
| ASN 3 | NTc.Cm26 | LYS 195 | 5.35x36 | HBAcceptor |
| ASN 3 | NTc.Cm26 | LYS 195 | 5.35x36 | VdWContact |
| ASN 3 | NTc.Cm26 | THR 279 | 7.32x31 | HBDonor |
| ASN 3 | NTc.Cm26 | THR 279 | 7.32x31 | Hydrophobic |
| ASN 3 | NTc.Cm26 | THR 279 | 7.32x31 | VdWContact |
| ASP 4 | NTc.Cm25 | TYR 184 | 45.51x51 | Hydrophobic |
| ASP 4 | NTc.Cm25 | TYR 184 | 45.51x51 | VdWContact |
| ASP 4 | NTc.Cm25 | LYS 195 | 5.35x36 | VdWContact |
| ALA 5 | NTc.Cm24 | LYS 195 | 5.35x36 | HBAcceptor |
| ALA 5 | NTc.Cm24 | LYS 195 | 5.35x36 | VdWContact |
| ASP 7 | NTc.Cm22 | PRO 24 | - | Hydrophobic |
| ASP 7 | NTc.Cm22 | PRO 24 | - | VdWContact |
| ASP 7 | NTc.Cm22 | CYS 25 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ASP 26 | - | VdWContact |
| ASP 7 | NTc.Cm22 | ALA 27 | - | HBAcceptor |
| ASP 7 | NTc.Cm22 | ALA 27 | - | VdWContact |
| CYS 8 | NTc.Cm21 | CYS 25 | - | HBAcceptor |
| CYS 8 | NTc.Cm21 | CYS 25 | - | VdWContact |
| LEU 10 | NTc.Cm19 | CYS 25 | - | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 272 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm19 | CYS 272 | 7.25x24 | VdWContact |
| SER 11 | NTc.Cm18 | SER 22 | - | VdWContact |
| THR 13 | NTc.Cm16 | PHE 21 | - | Hydrophobic |
| THR 13 | NTc.Cm16 | PHE 21 | - | VdWContact |
| LYS 15 | NTc.Cm14 | ILE 20 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | ILE 20 | - | VdWContact |
| LYS 15 | NTc.Cm14 | PHE 21 | - | Hydrophobic |
| LYS 15 | NTc.Cm14 | PHE 21 | - | VdWContact |
| ILE 17 | NTc.Cm12 | PHE 21 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | TYR 15 | - | HBDonor |
| TYR 20 | NTc.Cm9 | TYR 15 | - | Hydrophobic |
| TYR 20 | NTc.Cm9 | TYR 15 | - | VdWContact |
| ILE 21 | NTc.Cm8 | TYR 17 | - | Hydrophobic |
| ILE 21 | NTc.Cm8 | TYR 17 | - | VdWContact |
| HIS 26 | NTc.Cm3 | ASP 178 | - | HBDonor |
| LYS 31 | cxb1.1 | GLN 189 | - | HBDonor |
| LYS 31 | cxb1.1 | GLN 189 | - | Hydrophobic |
| LYS 31 | cxb1.1 | GLN 189 | - | VdWContact |
| GLY 33 | cxb1.5 | LEU 192 | 5.32x33 | VdWContact |
| GLY 33 | cxb1.5 | HIS 267 | 6.64x64 | VdWContact |
| ARG 35 | cxb1.8 | HIS 267 | 6.64x64 | Hydrophobic |
| ARG 35 | cxb1.8 | HIS 267 | 6.64x64 | VdWContact |
| ARG 35 | cxb1.8 | ASP 270 | - | Cationic |
| ARG 35 | cxb1.8 | ASP 270 | - | HBDonor |
| ARG 35 | cxb1.8 | ASP 270 | - | VdWContact |
| VAL 40 | cxb1.15 | PRO 24 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 17 | - | Hydrophobic |
| THR 43 | B1.2 | TYR 17 | - | VdWContact |
| ARG 45 | B1.4 | ASP 14 | - | Cationic |
| ARG 45 | B1.4 | ASP 14 | - | HBDonor |
| ARG 45 | B1.4 | ASP 14 | - | VdWContact |
| ARG 47 | B1.6 | ASP 19 | - | Cationic |
| ARG 47 | B1.6 | ASP 19 | - | HBDonor |
| ARG 47 | B1.6 | ASP 19 | - | VdWContact |
| GLN 48 | B1.7 | PRO 24 | - | Hydrophobic |
| GLN 48 | B1.7 | PRO 24 | - | VdWContact |
| GLN 48 | B1.7 | ASP 178 | - | VdWContact |
| LEU 49 | b1b2.4 | TYR 17 | - | Hydrophobic |
| LEU 49 | b1b2.4 | TYR 17 | - | VdWContact |
| LEU 49 | b1b2.4 | PHE 21 | - | Hydrophobic |
| LEU 49 | b1b2.4 | PHE 21 | - | VdWContact |
| CYS 50 | b1b2.6 | SER 22 | - | HBDonor |
| CYS 50 | b1b2.6 | SER 22 | - | VdWContact |
| CYS 50 | b1b2.6 | SER 23 | - | VdWContact |
| CYS 50 | b1b2.6 | PRO 24 | - | VdWContact |
