Predicted complex interactions
CCL21_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL21_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 73
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm30 | TYR 42 | 1.39x39 | HBAcceptor |
| SER 1 | NTc.Cm30 | GLU 286 | 7.39x38 | Cationic |
| SER 1 | NTc.Cm30 | GLU 286 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm30 | GLU 286 | 7.39x38 | VdWContact |
| ASP 2 | NTc.Cm29 | TYR 184 | 45.51x51 | VdWContact |
| ASP 2 | NTc.Cm29 | LYS 195 | 5.35x36 | Anionic |
| ASP 2 | NTc.Cm29 | LYS 195 | 5.35x36 | HBAcceptor |
| ASP 2 | NTc.Cm29 | LYS 195 | 5.35x36 | VdWContact |
| GLY 4 | NTc.Cm27 | GLU 28 | - | VdWContact |
| GLY 4 | NTc.Cm27 | GLN 182 | - | HBAcceptor |
| GLY 4 | NTc.Cm27 | GLN 182 | - | VdWContact |
| ALA 5 | NTc.Cm26 | ALA 27 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | ALA 27 | - | VdWContact |
| ALA 5 | NTc.Cm26 | GLU 28 | - | HBAcceptor |
| ALA 5 | NTc.Cm26 | GLU 28 | - | Hydrophobic |
| ALA 5 | NTc.Cm26 | GLU 28 | - | VdWContact |
| GLN 6 | NTc.Cm25 | GLU 177 | - | VdWContact |
| GLN 6 | NTc.Cm25 | ASP 178 | - | Hydrophobic |
| GLN 6 | NTc.Cm25 | ASP 178 | - | VdWContact |
| ASP 7 | NTc.Cm24 | PRO 24 | - | Hydrophobic |
| ASP 7 | NTc.Cm24 | PRO 24 | - | VdWContact |
| ASP 7 | NTc.Cm24 | CYS 25 | - | VdWContact |
| ASP 7 | NTc.Cm24 | ASP 26 | - | VdWContact |
| CYS 8 | NTc.Cm23 | CYS 25 | - | HBAcceptor |
| CYS 8 | NTc.Cm23 | CYS 25 | - | HBDonor |
| CYS 8 | NTc.Cm23 | CYS 25 | - | VdWContact |
| LEU 10 | NTc.Cm21 | CYS 25 | - | Hydrophobic |
| LEU 10 | NTc.Cm21 | HIS 264 | 6.61x61 | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| LEU 10 | NTc.Cm21 | CYS 272 | 7.25x24 | VdWContact |
| ARG 15 | NTc.Cm16 | PRO 18 | - | Hydrophobic |
| ARG 15 | NTc.Cm16 | PRO 18 | - | VdWContact |
| ILE 17 | NTc.Cm14 | TYR 17 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | PRO 18 | - | Hydrophobic |
| ILE 17 | NTc.Cm14 | PRO 18 | - | VdWContact |
| PRO 18 | NTc.Cm13 | TYR 15 | - | Hydrophobic |
| PRO 18 | NTc.Cm13 | TYR 15 | - | VdWContact |
| LYS 20 | NTc.Cm11 | TYR 15 | - | VdWContact |
| VAL 21 | NTc.Cm10 | TYR 17 | - | Hydrophobic |
| SER 31 | CX.1 | GLU 177 | - | HBDonor |
| SER 31 | CX.1 | GLU 177 | - | VdWContact |
| LEU 32 | CX.5 | TYR 184 | 45.51x51 | Hydrophobic |
| LEU 32 | CX.5 | TYR 184 | 45.51x51 | VdWContact |
| LEU 32 | CX.5 | PHE 186 | - | Hydrophobic |
| LEU 32 | CX.5 | PHE 186 | - | VdWContact |
| LEU 32 | CX.5 | THR 191 | 5.31x32 | Hydrophobic |
| LEU 32 | CX.5 | THR 191 | 5.31x32 | VdWContact |
| LEU 32 | CX.5 | LYS 195 | 5.35x36 | HBAcceptor |
| LEU 32 | CX.5 | LYS 195 | 5.35x36 | Hydrophobic |
| LEU 32 | CX.5 | LYS 195 | 5.35x36 | VdWContact |
| SER 35 | cxb1.5 | HIS 267 | 6.64x64 | HBDonor |
| SER 35 | cxb1.5 | HIS 267 | 6.64x64 | VdWContact |
| ILE 36 | cxb1.6 | HIS 267 | 6.64x64 | Hydrophobic |
| LEU 40 | cxb1.11 | PRO 24 | - | Hydrophobic |
| PRO 43 | cxb1.16 | TYR 17 | - | Hydrophobic |
| PRO 43 | cxb1.16 | TYR 17 | - | VdWContact |
| GLN 48 | B1.5 | TYR 17 | - | Hydrophobic |
| GLN 48 | B1.5 | TYR 17 | - | VdWContact |
| ALA 49 | B1.6 | TYR 17 | - | VdWContact |
| GLU 50 | B1.7 | SER 23 | - | VdWContact |
| GLU 50 | B1.7 | PRO 24 | - | Hydrophobic |
| GLU 50 | B1.7 | PRO 24 | - | VdWContact |
| LEU 51 | b1b2.4 | TYR 17 | - | Hydrophobic |
| LEU 51 | b1b2.4 | PRO 18 | - | Hydrophobic |
| LEU 51 | b1b2.4 | PRO 18 | - | VdWContact |
| LEU 51 | b1b2.4 | SER 22 | - | VdWContact |
| CYS 52 | b1b2.6 | SER 22 | - | HBDonor |
| CYS 52 | b1b2.6 | SER 22 | - | VdWContact |
| LYS 75 | B3.3 | ASP 178 | - | Cationic |
| LYS 75 | B3.3 | ASP 178 | - | HBDonor |
| LYS 75 | B3.3 | ASP 178 | - | VdWContact |
| GLN 78 | b3h.2 | SER 176 | - | HBDonor |
| GLN 78 | b3h.2 | SER 176 | - | VdWContact |
