Predicted complex interactions
CCL22_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | PHE 254 | 6.51x51 | VdWContact |
| GLY 1 | NTc.Cm35 | THR 282 | 7.35x34 | VdWContact |
| GLY 1 | NTc.Cm35 | GLU 286 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm35 | GLU 286 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm35 | GLU 286 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 113 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 114 | 3.33x33 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TYR 114 | 3.33x33 | VdWContact |
| PRO 2 | NTc.Cm34 | MET 202 | 5.42x43 | Hydrophobic |
| PRO 2 | NTc.Cm34 | MET 202 | 5.42x43 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 254 | 6.51x51 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LEU 258 | 6.55x55 | Hydrophobic |
| PRO 2 | NTc.Cm34 | LEU 258 | 6.55x55 | VdWContact |
| TYR 3 | NTc.Cm33 | SER 87 | 2.56x56 | HBDonor |
| TYR 3 | NTc.Cm33 | SER 87 | 2.56x56 | VdWContact |
| TYR 3 | NTc.Cm33 | TRP 99 | 23.50x50 | Hydrophobic |
| TYR 3 | NTc.Cm33 | VAL 109 | 3.28x28 | Hydrophobic |
| TYR 3 | NTc.Cm33 | VAL 109 | 3.28x28 | VdWContact |
| TYR 3 | NTc.Cm33 | SER 110 | 3.29x29 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 113 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 113 | 3.32x32 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 114 | 3.33x33 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 172 | 4.64x65 | HBAcceptor |
| TYR 3 | NTc.Cm33 | TYR 172 | 4.64x65 | Hydrophobic |
| TYR 3 | NTc.Cm33 | TYR 172 | 4.64x65 | VdWContact |
| ALA 5 | NTc.Cm31 | HIS 283 | 7.36x35 | Hydrophobic |
| ALA 5 | NTc.Cm31 | HIS 283 | 7.36x35 | VdWContact |
| ASN 6 | NTc.Cm30 | LYS 195 | 5.35x36 | VdWContact |
| ASN 6 | NTc.Cm30 | THR 279 | 7.32x31 | Hydrophobic |
| MET 7 | NTc.Cm29 | TYR 94 | 2.63x63 | Hydrophobic |
| MET 7 | NTc.Cm29 | TYR 94 | 2.63x63 | VdWContact |
| MET 7 | NTc.Cm29 | GLN 182 | - | Hydrophobic |
| GLU 8 | NTc.Cm28 | ALA 27 | - | VdWContact |
| GLU 8 | NTc.Cm28 | LYS 195 | 5.35x36 | Anionic |
| GLU 8 | NTc.Cm28 | LYS 195 | 5.35x36 | VdWContact |
| ASP 9 | NTc.Cm27 | GLU 28 | - | Hydrophobic |
| ASP 9 | NTc.Cm27 | GLU 28 | - | VdWContact |
| SER 10 | NTc.Cm26 | ASP 178 | - | VdWContact |
| VAL 11 | NTc.Cm25 | PRO 24 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | PRO 24 | - | VdWContact |
| VAL 11 | NTc.Cm25 | ASP 26 | - | VdWContact |
| VAL 11 | NTc.Cm25 | ASP 178 | - | HBDonor |
| VAL 11 | NTc.Cm25 | ASP 178 | - | VdWContact |
| CYS 12 | NTc.Cm24 | CYS 25 | - | HBAcceptor |
| CYS 12 | NTc.Cm24 | CYS 25 | - | HBDonor |
| CYS 12 | NTc.Cm24 | CYS 25 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 25 | - | Cationic |
| ARG 14 | NTc.Cm22 | HIS 264 | 6.61x61 | VdWContact |
| ARG 14 | NTc.Cm22 | GLY 271 | 7.24x23 | HBDonor |
| ARG 14 | NTc.Cm22 | GLY 271 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | SER 275 | 7.28x27 | HBDonor |
| ARG 14 | NTc.Cm22 | SER 275 | 7.28x27 | VdWContact |
| TYR 19 | NTc.Cm17 | TYR 16 | - | HBDonor |
| TYR 19 | NTc.Cm17 | TYR 16 | - | VdWContact |
| TYR 19 | NTc.Cm17 | PRO 18 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | PRO 18 | - | VdWContact |
| TYR 19 | NTc.Cm17 | ILE 20 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TYR 16 | - | Hydrophobic |
| PRO 22 | NTc.Cm14 | TYR 16 | - | VdWContact |
| ARG 24 | NTc.Cm12 | VAL 12 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TYR 17 | - | Hydrophobic |
| SER 33 | NTc.Cm3 | GLU 177 | - | VdWContact |
| PRO 37 | CX.5 | HIS 267 | 6.64x64 | Hydrophobic |
| VAL 42 | cxb1.7 | PRO 24 | - | Hydrophobic |
| VAL 42 | cxb1.7 | PRO 24 | - | VdWContact |
| THR 45 | cxb1.11 | TYR 17 | - | Hydrophobic |
| THR 45 | cxb1.11 | TYR 17 | - | VdWContact |
| ARG 47 | cxb1.15 | THR 13 | - | VdWContact |
| ARG 47 | cxb1.15 | ASP 14 | - | Cationic |
| ARG 47 | cxb1.15 | ASP 14 | - | HBDonor |
| ARG 47 | cxb1.15 | ASP 14 | - | VdWContact |
| ARG 47 | cxb1.15 | TYR 17 | - | Hydrophobic |
| ARG 47 | cxb1.15 | TYR 17 | - | VdWContact |
| LYS 49 | B1.1 | TYR 17 | - | Hydrophobic |
| LYS 49 | B1.1 | TYR 17 | - | VdWContact |
| LYS 49 | B1.1 | ILE 20 | - | Hydrophobic |
| LYS 49 | B1.1 | ILE 20 | - | VdWContact |
| GLU 50 | B1.2 | SER 23 | - | VdWContact |
| GLU 50 | B1.2 | PRO 24 | - | Hydrophobic |
| GLU 50 | B1.2 | PRO 24 | - | VdWContact |
| ILE 51 | B1.3 | ILE 20 | - | Hydrophobic |
| ILE 51 | B1.3 | ILE 20 | - | VdWContact |
| CYS 52 | B1.4 | SER 22 | - | HBDonor |
| CYS 52 | B1.4 | SER 22 | - | VdWContact |
