Predicted complex interactions
CCL23_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL23_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 126
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 14 | NTc.Cm57 | ASP 178 | - | HBDonor |
| LYS 14 | NTc.Cm57 | ASP 178 | - | VdWContact |
| LYS 14 | NTc.Cm57 | GLY 179 | - | HBDonor |
| LYS 14 | NTc.Cm57 | GLY 179 | - | VdWContact |
| PRO 20 | NTc.Cm51 | GLU 28 | - | Hydrophobic |
| PRO 20 | NTc.Cm51 | GLU 28 | - | VdWContact |
| VAL 21 | NTc.Cm50 | GLU 28 | - | HBDonor |
| VAL 21 | NTc.Cm50 | GLU 28 | - | VdWContact |
| VAL 21 | NTc.Cm50 | LYS 35 | 1.32x32 | Hydrophobic |
| VAL 21 | NTc.Cm50 | LYS 35 | 1.32x32 | VdWContact |
| LEU 22 | NTc.Cm49 | GLU 28 | - | VdWContact |
| LEU 22 | NTc.Cm49 | LYS 35 | 1.32x32 | HBAcceptor |
| LEU 22 | NTc.Cm49 | LYS 35 | 1.32x32 | VdWContact |
| LEU 22 | NTc.Cm49 | VAL 180 | - | Hydrophobic |
| LEU 22 | NTc.Cm49 | VAL 180 | - | VdWContact |
| LEU 22 | NTc.Cm49 | GLN 182 | - | VdWContact |
| LEU 23 | NTc.Cm48 | ILE 30 | - | Hydrophobic |
| LEU 23 | NTc.Cm48 | ILE 30 | - | VdWContact |
| LEU 23 | NTc.Cm48 | LYS 35 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm48 | LYS 35 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm48 | LEU 95 | 2.64x64 | Hydrophobic |
| LEU 23 | NTc.Cm48 | LEU 95 | 2.64x64 | VdWContact |
| LEU 23 | NTc.Cm48 | HIS 283 | 7.36x35 | Hydrophobic |
| LEU 23 | NTc.Cm48 | HIS 283 | 7.36x35 | VdWContact |
| ASP 24 | NTc.Cm47 | TYR 94 | 2.63x63 | Hydrophobic |
| ASP 24 | NTc.Cm47 | TYR 94 | 2.63x63 | VdWContact |
| ASP 24 | NTc.Cm47 | GLN 182 | - | Hydrophobic |
| ASP 24 | NTc.Cm47 | GLN 182 | - | VdWContact |
| ARG 25 | NTc.Cm46 | LEU 38 | 1.35x35 | VdWContact |
| ARG 25 | NTc.Cm46 | HIS 283 | 7.36x35 | HBDonor |
| ARG 25 | NTc.Cm46 | HIS 283 | 7.36x35 | Hydrophobic |
| ARG 25 | NTc.Cm46 | HIS 283 | 7.36x35 | VdWContact |
| ARG 25 | NTc.Cm46 | GLU 286 | 7.39x38 | Cationic |
| ARG 25 | NTc.Cm46 | GLU 286 | 7.39x38 | HBDonor |
| ARG 25 | NTc.Cm46 | GLU 286 | 7.39x38 | VdWContact |
| PHE 26 | NTc.Cm45 | GLN 91 | 2.60x60 | Hydrophobic |
| PHE 26 | NTc.Cm45 | GLN 91 | 2.60x60 | VdWContact |
| PHE 26 | NTc.Cm45 | TRP 99 | 23.50x50 | Hydrophobic |
| PHE 26 | NTc.Cm45 | VAL 109 | 3.28x28 | Hydrophobic |
| PHE 26 | NTc.Cm45 | SER 110 | 3.29x29 | VdWContact |
| PHE 26 | NTc.Cm45 | TYR 172 | 4.64x65 | HBAcceptor |
| PHE 26 | NTc.Cm45 | TYR 172 | 4.64x65 | Hydrophobic |
| PHE 26 | NTc.Cm45 | TYR 172 | 4.64x65 | VdWContact |
| PHE 26 | NTc.Cm45 | TYR 184 | 45.51x51 | VdWContact |
| HIS 27 | NTc.Cm44 | TYR 113 | 3.32x32 | HBAcceptor |
| HIS 27 | NTc.Cm44 | TYR 113 | 3.32x32 | Hydrophobic |
| HIS 27 | NTc.Cm44 | TYR 113 | 3.32x32 | VdWContact |
| HIS 27 | NTc.Cm44 | TYR 114 | 3.33x33 | Hydrophobic |
| HIS 27 | NTc.Cm44 | TYR 114 | 3.33x33 | VdWContact |
| HIS 27 | NTc.Cm44 | MET 202 | 5.42x43 | Hydrophobic |
| HIS 27 | NTc.Cm44 | MET 202 | 5.42x43 | VdWContact |
| HIS 27 | NTc.Cm44 | PHE 254 | 6.51x51 | Hydrophobic |
| HIS 27 | NTc.Cm44 | PHE 254 | 6.51x51 | PiStacking |
| HIS 27 | NTc.Cm44 | THR 282 | 7.35x34 | Hydrophobic |
| HIS 27 | NTc.Cm44 | GLU 286 | 7.39x38 | VdWContact |
| ALA 28 | NTc.Cm43 | HIS 283 | 7.36x35 | Hydrophobic |
| THR 29 | NTc.Cm42 | GLN 182 | - | VdWContact |
| THR 29 | NTc.Cm42 | TYR 184 | 45.51x51 | Hydrophobic |
| THR 29 | NTc.Cm42 | PHE 186 | - | Hydrophobic |
| SER 30 | NTc.Cm41 | ALA 27 | - | VdWContact |
| SER 30 | NTc.Cm41 | GLU 28 | - | HBDonor |
| SER 30 | NTc.Cm41 | GLU 28 | - | VdWContact |
| ASP 32 | NTc.Cm39 | PRO 24 | - | Hydrophobic |
| ASP 32 | NTc.Cm39 | CYS 25 | - | VdWContact |
| ASP 32 | NTc.Cm39 | ASP 26 | - | VdWContact |
| CYS 33 | NTc.Cm38 | CYS 25 | - | HBAcceptor |
| CYS 33 | NTc.Cm38 | CYS 25 | - | HBDonor |
| CYS 33 | NTc.Cm38 | CYS 25 | - | VdWContact |
| ILE 35 | NTc.Cm36 | CYS 25 | - | Hydrophobic |
| ILE 35 | NTc.Cm36 | HIS 264 | 6.61x61 | Hydrophobic |
| ILE 35 | NTc.Cm36 | GLY 271 | 7.24x23 | VdWContact |
| ILE 35 | NTc.Cm36 | CYS 272 | 7.25x24 | Hydrophobic |
| SER 36 | NTc.Cm35 | PHE 21 | - | HBDonor |
| SER 36 | NTc.Cm35 | PHE 21 | - | VdWContact |
| ARG 40 | NTc.Cm31 | TYR 15 | - | HBDonor |
| ARG 40 | NTc.Cm31 | TYR 15 | - | VdWContact |
| ARG 40 | NTc.Cm31 | ASP 19 | - | Cationic |
| ILE 42 | NTc.Cm29 | TYR 16 | - | VdWContact |
| ILE 42 | NTc.Cm29 | PRO 18 | - | Hydrophobic |
| ILE 42 | NTc.Cm29 | PRO 18 | - | VdWContact |
| PRO 43 | NTc.Cm28 | TYR 16 | - | Hydrophobic |
| PRO 43 | NTc.Cm28 | TYR 16 | - | VdWContact |
| LEU 46 | NTc.Cm25 | TYR 16 | - | Hydrophobic |
| PHE 51 | NTc.Cm20 | ASP 178 | - | VdWContact |
| ASN 54 | NTc.Cm17 | PHE 186 | - | VdWContact |
| SER 55 | NTc.Cm16 | GLN 189 | - | VdWContact |
| SER 55 | NTc.Cm16 | THR 191 | 5.31x32 | HBAcceptor |
| SER 55 | NTc.Cm16 | THR 191 | 5.31x32 | VdWContact |
| SER 55 | NTc.Cm16 | LEU 192 | 5.32x33 | HBAcceptor |
| SER 55 | NTc.Cm16 | LEU 192 | 5.32x33 | VdWContact |
| GLU 56 | NTc.Cm15 | TYR 184 | 45.51x51 | HBAcceptor |
| GLU 56 | NTc.Cm15 | TYR 184 | 45.51x51 | Hydrophobic |
| GLU 56 | NTc.Cm15 | TYR 184 | 45.51x51 | VdWContact |
| GLU 56 | NTc.Cm15 | THR 191 | 5.31x32 | Hydrophobic |
| GLU 56 | NTc.Cm15 | LEU 192 | 5.32x33 | VdWContact |
| GLU 56 | NTc.Cm15 | LYS 195 | 5.35x36 | Anionic |
| GLU 56 | NTc.Cm15 | LYS 195 | 5.35x36 | HBAcceptor |
| GLU 56 | NTc.Cm15 | LYS 195 | 5.35x36 | Hydrophobic |
| GLU 56 | NTc.Cm15 | LYS 195 | 5.35x36 | VdWContact |
| SER 58 | NTc.Cm13 | HIS 267 | 6.64x64 | VdWContact |
| LYS 59 | NTc.Cm12 | HIS 267 | 6.64x64 | Hydrophobic |
| LYS 59 | NTc.Cm12 | HIS 267 | 6.64x64 | VdWContact |
| ILE 63 | NTc.Cm8 | PRO 24 | - | Hydrophobic |
| ILE 63 | NTc.Cm8 | PRO 24 | - | VdWContact |
| THR 66 | NTc.Cm5 | TYR 17 | - | Hydrophobic |
| THR 66 | NTc.Cm5 | TYR 17 | - | VdWContact |
| LYS 68 | NTc.Cm3 | THR 13 | - | HBDonor |
| LYS 68 | NTc.Cm3 | THR 13 | - | VdWContact |
| LYS 68 | NTc.Cm3 | ASP 14 | - | Cationic |
| LYS 68 | NTc.Cm3 | ASP 14 | - | HBDonor |
| LYS 68 | NTc.Cm3 | ASP 14 | - | VdWContact |
| LYS 68 | NTc.Cm3 | TYR 17 | - | Hydrophobic |
| LYS 68 | NTc.Cm3 | TYR 17 | - | VdWContact |
| ARG 70 | NTc.Cm1 | TYR 17 | - | Hydrophobic |
| ARG 70 | NTc.Cm1 | TYR 17 | - | VdWContact |
| ARG 70 | NTc.Cm1 | PRO 18 | - | VdWContact |
| ARG 71 | CX.1 | PRO 24 | - | Hydrophobic |
| ARG 71 | CX.1 | ASP 26 | - | Cationic |
| ARG 71 | CX.1 | ASP 26 | - | HBDonor |
| ARG 71 | CX.1 | ASP 26 | - | VdWContact |
| PHE 72 | CX.5 | PRO 18 | - | Hydrophobic |
| PHE 72 | CX.5 | PRO 18 | - | VdWContact |
| PHE 72 | CX.5 | SER 22 | - | VdWContact |
| CYS 73 | cxb1.1 | SER 22 | - | HBDonor |
| CYS 73 | cxb1.1 | SER 22 | - | VdWContact |
| CYS 73 | cxb1.1 | PRO 24 | - | VdWContact |
