Predicted complex interactions
CCL25_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 78
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | THR 282 | 7.35x34 | VdWContact |
| GLN 1 | NTc.Cm29 | HIS 283 | 7.36x35 | Hydrophobic |
| GLN 1 | NTc.Cm29 | GLU 286 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 286 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | GLU 28 | - | VdWContact |
| PHE 4 | NTc.Cm26 | ALA 27 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLU 28 | - | HBDonor |
| PHE 4 | NTc.Cm26 | GLU 28 | - | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLU 28 | - | VdWContact |
| PHE 4 | NTc.Cm26 | THR 279 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | HIS 283 | 7.36x35 | Hydrophobic |
| ASP 6 | NTc.Cm24 | PRO 24 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | PRO 24 | - | VdWContact |
| ASP 6 | NTc.Cm24 | CYS 25 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 25 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 25 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 25 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 25 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | HIS 264 | 6.61x61 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 272 | 7.25x24 | VdWContact |
| LEU 9 | NTc.Cm21 | SER 275 | 7.28x27 | VdWContact |
| ALA 10 | NTc.Cm20 | SER 22 | - | HBAcceptor |
| ALA 10 | NTc.Cm20 | SER 22 | - | VdWContact |
| HIS 12 | NTc.Cm18 | ILE 20 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | ILE 20 | - | VdWContact |
| HIS 12 | NTc.Cm18 | PHE 21 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | PHE 21 | - | VdWContact |
| HIS 12 | NTc.Cm18 | SER 22 | - | VdWContact |
| ILE 15 | NTc.Cm15 | PHE 21 | - | Hydrophobic |
| ALA 18 | NTc.Cm12 | TYR 15 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | TYR 17 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | PHE 21 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | PHE 21 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 15 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 17 | - | VdWContact |
| ARG 27 | NTc.Cm3 | ASP 178 | - | Cationic |
| ARG 27 | NTc.Cm3 | ASP 178 | - | HBDonor |
| ARG 27 | NTc.Cm3 | ASP 178 | - | VdWContact |
| GLU 30 | CX.1 | GLN 189 | - | HBAcceptor |
| GLU 30 | CX.1 | GLN 189 | - | VdWContact |
| VAL 31 | CX.5 | THR 191 | 5.31x32 | HBAcceptor |
| VAL 31 | CX.5 | THR 191 | 5.31x32 | Hydrophobic |
| VAL 31 | CX.5 | THR 191 | 5.31x32 | VdWContact |
| VAL 31 | CX.5 | LEU 192 | 5.32x33 | Hydrophobic |
| VAL 31 | CX.5 | LEU 192 | 5.32x33 | VdWContact |
| SER 32 | cxb1.1 | GLU 177 | - | HBDonor |
| SER 32 | cxb1.1 | GLU 177 | - | VdWContact |
| SER 32 | cxb1.1 | TYR 184 | 45.51x51 | VdWContact |
| SER 32 | cxb1.1 | THR 191 | 5.31x32 | VdWContact |
| GLY 33 | cxb1.2 | TYR 184 | 45.51x51 | VdWContact |
| GLY 33 | cxb1.2 | LYS 195 | 5.35x36 | HBAcceptor |
| GLY 33 | cxb1.2 | LYS 195 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | LEU 192 | 5.32x33 | Hydrophobic |
| ASN 36 | cxb1.8 | LEU 192 | 5.32x33 | VdWContact |
| ASN 36 | cxb1.8 | LYS 195 | 5.35x36 | HBAcceptor |
| ASN 36 | cxb1.8 | LYS 195 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | SER 265 | 6.62x62 | HBDonor |
| ASN 36 | cxb1.8 | SER 265 | 6.62x62 | VdWContact |
| LEU 37 | cxb1.10 | HIS 267 | 6.64x64 | Hydrophobic |
| ILE 41 | cxb1.16 | PRO 24 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 17 | - | Hydrophobic |
| LYS 46 | B1.5 | ASP 14 | - | Cationic |
| LYS 46 | B1.5 | ASP 14 | - | HBDonor |
| LYS 46 | B1.5 | ASP 14 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 17 | - | HBDonor |
| ARG 49 | b1b2.1 | TYR 17 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 19 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 19 | - | HBDonor |
| ARG 49 | b1b2.1 | ASP 19 | - | VdWContact |
| LYS 50 | b1b2.2 | SER 23 | - | VdWContact |
| LYS 50 | b1b2.2 | PRO 24 | - | Hydrophobic |
| LYS 50 | b1b2.2 | PRO 24 | - | VdWContact |
| VAL 51 | b1b2.3 | PHE 21 | - | Hydrophobic |
| CYS 52 | b1b2.4 | SER 22 | - | HBDonor |
| CYS 52 | b1b2.4 | SER 22 | - | VdWContact |
| CYS 52 | b1b2.4 | SER 23 | - | VdWContact |
