Predicted complex interactions
CCL27_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL27_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 70
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| PHE 1 | NTc.Cm32 | GLN 91 | 2.60x60 | Hydrophobic |
| PHE 1 | NTc.Cm32 | GLN 91 | 2.60x60 | VdWContact |
| PHE 1 | NTc.Cm32 | TRP 99 | 23.50x50 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TRP 99 | 23.50x50 | VdWContact |
| PHE 1 | NTc.Cm32 | VAL 109 | 3.28x28 | Hydrophobic |
| PHE 1 | NTc.Cm32 | VAL 109 | 3.28x28 | VdWContact |
| PHE 1 | NTc.Cm32 | SER 110 | 3.29x29 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 172 | 4.64x65 | HBAcceptor |
| PHE 1 | NTc.Cm32 | TYR 172 | 4.64x65 | Hydrophobic |
| PHE 1 | NTc.Cm32 | TYR 172 | 4.64x65 | VdWContact |
| PHE 1 | NTc.Cm32 | CYS 183 | 45.50x50 | VdWContact |
| PHE 1 | NTc.Cm32 | TYR 184 | 45.51x51 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 113 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 113 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 114 | 3.33x33 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 114 | 3.33x33 | VdWContact |
| LEU 2 | NTc.Cm31 | THR 198 | 5.38x39 | Hydrophobic |
| LEU 2 | NTc.Cm31 | MET 202 | 5.42x43 | Hydrophobic |
| LEU 2 | NTc.Cm31 | MET 202 | 5.42x43 | VdWContact |
| LEU 2 | NTc.Cm31 | PHE 254 | 6.51x51 | Hydrophobic |
| LEU 2 | NTc.Cm31 | PHE 254 | 6.51x51 | VdWContact |
| LEU 2 | NTc.Cm31 | LEU 258 | 6.55x55 | Hydrophobic |
| LEU 3 | NTc.Cm30 | THR 279 | 7.32x31 | Hydrophobic |
| LEU 3 | NTc.Cm30 | THR 282 | 7.35x34 | Hydrophobic |
| LEU 3 | NTc.Cm30 | THR 282 | 7.35x34 | VdWContact |
| LEU 3 | NTc.Cm30 | HIS 283 | 7.36x35 | Hydrophobic |
| LEU 3 | NTc.Cm30 | HIS 283 | 7.36x35 | VdWContact |
| PRO 4 | NTc.Cm29 | TYR 184 | 45.51x51 | Hydrophobic |
| PRO 4 | NTc.Cm29 | TYR 184 | 45.51x51 | VdWContact |
| PRO 4 | NTc.Cm29 | LYS 195 | 5.35x36 | Hydrophobic |
| PRO 4 | NTc.Cm29 | LYS 195 | 5.35x36 | VdWContact |
| PRO 5 | NTc.Cm28 | GLN 182 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | GLN 182 | - | VdWContact |
| PRO 5 | NTc.Cm28 | TYR 184 | 45.51x51 | Hydrophobic |
| PRO 5 | NTc.Cm28 | PHE 186 | - | Hydrophobic |
| PRO 5 | NTc.Cm28 | PHE 186 | - | VdWContact |
| SER 6 | NTc.Cm27 | GLU 28 | - | VdWContact |
| ALA 8 | NTc.Cm25 | PRO 24 | - | Hydrophobic |
| ALA 8 | NTc.Cm25 | PRO 24 | - | VdWContact |
| ALA 8 | NTc.Cm25 | CYS 25 | - | VdWContact |
| ALA 8 | NTc.Cm25 | ASP 26 | - | VdWContact |
| CYS 9 | NTc.Cm24 | CYS 25 | - | HBAcceptor |
| CYS 9 | NTc.Cm24 | CYS 25 | - | HBDonor |
| CYS 9 | NTc.Cm24 | CYS 25 | - | VdWContact |
| THR 11 | NTc.Cm22 | CYS 25 | - | Hydrophobic |
| GLN 12 | NTc.Cm21 | SER 22 | - | VdWContact |
| TYR 14 | NTc.Cm19 | ASP 19 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 21 | - | Hydrophobic |
| TYR 14 | NTc.Cm19 | PHE 21 | - | VdWContact |
| TYR 14 | NTc.Cm19 | SER 22 | - | VdWContact |
| LEU 18 | NTc.Cm15 | PHE 21 | - | Hydrophobic |
| LEU 18 | NTc.Cm15 | PHE 21 | - | VdWContact |
| LEU 22 | NTc.Cm11 | PHE 21 | - | Hydrophobic |
| LYS 25 | NTc.Cm8 | ASP 14 | - | Cationic |
| GLY 36 | cxb1.2 | LEU 192 | 5.32x33 | VdWContact |
| ASP 37 | cxb1.5 | THR 191 | 5.31x32 | VdWContact |
| HIS 39 | cxb1.7 | HIS 267 | 6.64x64 | Hydrophobic |
| HIS 39 | cxb1.7 | HIS 267 | 6.64x64 | PiStacking |
| HIS 39 | cxb1.7 | HIS 267 | 6.64x64 | VdWContact |
| VAL 44 | cxb1.15 | PRO 24 | - | Hydrophobic |
| ARG 50 | B1.2 | PHE 21 | - | VdWContact |
| SER 51 | B1.3 | SER 23 | - | VdWContact |
| SER 51 | B1.3 | PRO 24 | - | VdWContact |
| ILE 52 | B1.4 | PHE 21 | - | Hydrophobic |
| ILE 52 | B1.4 | SER 22 | - | VdWContact |
| CYS 53 | B1.5 | SER 22 | - | HBAcceptor |
| CYS 53 | B1.5 | SER 22 | - | HBDonor |
| CYS 53 | B1.5 | SER 22 | - | VdWContact |
| CYS 53 | B1.5 | SER 23 | - | VdWContact |
| CYS 53 | B1.5 | PRO 24 | - | VdWContact |
