Predicted complex interactions
CCL28_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL28_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 2 | NTc.Cm28 | LYS 195 | 5.35x36 | Anionic |
| GLU 2 | NTc.Cm28 | LYS 195 | 5.35x36 | Hydrophobic |
| GLU 2 | NTc.Cm28 | LYS 195 | 5.35x36 | VdWContact |
| GLU 2 | NTc.Cm28 | THR 198 | 5.38x39 | HBAcceptor |
| GLU 2 | NTc.Cm28 | THR 198 | 5.38x39 | VdWContact |
| GLU 2 | NTc.Cm28 | ASN 199 | 5.39x40 | VdWContact |
| ALA 3 | NTc.Cm27 | TYR 113 | 3.32x32 | Hydrophobic |
| ALA 3 | NTc.Cm27 | TYR 114 | 3.33x33 | Hydrophobic |
| ALA 3 | NTc.Cm27 | TYR 114 | 3.33x33 | VdWContact |
| ALA 3 | NTc.Cm27 | MET 202 | 5.42x43 | Hydrophobic |
| ILE 4 | NTc.Cm26 | GLN 91 | 2.60x60 | Hydrophobic |
| ILE 4 | NTc.Cm26 | SER 110 | 3.29x29 | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 113 | 3.32x32 | Hydrophobic |
| ILE 4 | NTc.Cm26 | TYR 113 | 3.32x32 | VdWContact |
| ILE 4 | NTc.Cm26 | TYR 114 | 3.33x33 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 42 | 1.39x39 | Hydrophobic |
| LEU 5 | NTc.Cm25 | TYR 42 | 1.39x39 | VdWContact |
| LEU 5 | NTc.Cm25 | GLN 91 | 2.60x60 | Hydrophobic |
| LEU 5 | NTc.Cm25 | GLN 91 | 2.60x60 | VdWContact |
| LEU 5 | NTc.Cm25 | TYR 94 | 2.63x63 | Hydrophobic |
| LEU 5 | NTc.Cm25 | LEU 95 | 2.64x64 | Hydrophobic |
| PRO 6 | NTc.Cm24 | HIS 283 | 7.36x35 | Hydrophobic |
| PRO 6 | NTc.Cm24 | HIS 283 | 7.36x35 | VdWContact |
| ILE 7 | NTc.Cm23 | TYR 94 | 2.63x63 | Hydrophobic |
| ILE 7 | NTc.Cm23 | TYR 94 | 2.63x63 | VdWContact |
| ILE 7 | NTc.Cm23 | VAL 180 | - | Hydrophobic |
| ILE 7 | NTc.Cm23 | GLN 182 | - | Hydrophobic |
| ALA 8 | NTc.Cm22 | ALA 27 | - | Hydrophobic |
| ALA 8 | NTc.Cm22 | ALA 27 | - | VdWContact |
| ALA 8 | NTc.Cm22 | GLU 28 | - | Hydrophobic |
| ALA 8 | NTc.Cm22 | GLU 28 | - | VdWContact |
| SER 9 | NTc.Cm21 | GLU 177 | - | VdWContact |
| SER 10 | NTc.Cm20 | CYS 25 | - | VdWContact |
| SER 10 | NTc.Cm20 | ASP 26 | - | HBDonor |
| SER 10 | NTc.Cm20 | ASP 26 | - | VdWContact |
| CYS 11 | NTc.Cm19 | CYS 25 | - | HBAcceptor |
| CYS 11 | NTc.Cm19 | CYS 25 | - | HBDonor |
| CYS 11 | NTc.Cm19 | CYS 25 | - | VdWContact |
| THR 13 | NTc.Cm17 | CYS 25 | - | Hydrophobic |
| THR 13 | NTc.Cm17 | HIS 264 | 6.61x61 | Hydrophobic |
| GLU 14 | NTc.Cm16 | GLY 271 | 7.24x23 | VdWContact |
| SER 16 | NTc.Cm14 | PHE 21 | - | VdWContact |
| SER 16 | NTc.Cm14 | SER 22 | - | HBAcceptor |
| SER 16 | NTc.Cm14 | SER 22 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 15 | - | HBDonor |
| ARG 22 | NTc.Cm8 | TYR 15 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 17 | - | VdWContact |
| LEU 23 | NTc.Cm7 | TYR 17 | - | Hydrophobic |
| LEU 23 | NTc.Cm7 | TYR 17 | - | VdWContact |
| LEU 23 | NTc.Cm7 | PHE 21 | - | Hydrophobic |
| ARG 26 | NTc.Cm4 | TYR 15 | - | VdWContact |
| ARG 26 | NTc.Cm4 | TYR 17 | - | HBDonor |
| ARG 26 | NTc.Cm4 | TYR 17 | - | VdWContact |
| ARG 31 | CX.5 | ASP 178 | - | Cationic |
| ARG 31 | CX.5 | ASP 178 | - | HBDonor |
| ARG 31 | CX.5 | ASP 178 | - | VdWContact |
| ASP 36 | cxb1.7 | PHE 186 | - | Hydrophobic |
| ASP 36 | cxb1.7 | PHE 186 | - | VdWContact |
| ASP 36 | cxb1.7 | THR 191 | 5.31x32 | HBAcceptor |
| ASP 36 | cxb1.7 | THR 191 | 5.31x32 | VdWContact |
| GLY 37 | cxb1.8 | THR 191 | 5.31x32 | VdWContact |
| ASP 38 | cxb1.10 | TYR 184 | 45.51x51 | Hydrophobic |
| ASP 40 | cxb1.12 | LEU 192 | 5.32x33 | Hydrophobic |
| ASP 40 | cxb1.12 | LYS 195 | 5.35x36 | Anionic |
| ASP 40 | cxb1.12 | LYS 195 | 5.35x36 | HBAcceptor |
| ASP 40 | cxb1.12 | LYS 195 | 5.35x36 | VdWContact |
| ASP 40 | cxb1.12 | SER 265 | 6.62x62 | HBAcceptor |
| ASP 40 | cxb1.12 | SER 265 | 6.62x62 | VdWContact |
| LEU 41 | cxb1.13 | HIS 267 | 6.64x64 | Hydrophobic |
| LEU 41 | cxb1.13 | HIS 267 | 6.64x64 | VdWContact |
| ILE 45 | B1.1 | PRO 24 | - | Hydrophobic |
| LYS 49 | B1.5 | ASP 14 | - | Cationic |
| LYS 49 | B1.5 | ASP 14 | - | HBDonor |
| LYS 49 | B1.5 | ASP 14 | - | VdWContact |
| ARG 51 | B1.7 | ASP 19 | - | Cationic |
| ARG 51 | B1.7 | ASP 19 | - | HBDonor |
| ARG 51 | B1.7 | ASP 19 | - | VdWContact |
| ARG 52 | b1b2.4 | PRO 24 | - | Hydrophobic |
| ILE 53 | b1b2.6 | PHE 21 | - | Hydrophobic |
| ILE 53 | b1b2.6 | PHE 21 | - | VdWContact |
| CYS 54 | b1b2.7 | SER 22 | - | HBDonor |
| CYS 54 | b1b2.7 | SER 22 | - | VdWContact |
| CYS 54 | b1b2.7 | SER 23 | - | VdWContact |
| CYS 54 | b1b2.7 | PRO 24 | - | VdWContact |
| LYS 83 | H.5 | GLU 177 | - | Cationic |
| LYS 83 | H.5 | GLU 177 | - | HBDonor |
| LYS 83 | H.5 | GLU 177 | - | Hydrophobic |
| LYS 83 | H.5 | GLU 177 | - | VdWContact |
| HIS 85 | H.7 | TYR 184 | 45.51x51 | Hydrophobic |
| HIS 85 | H.7 | TYR 184 | 45.51x51 | VdWContact |
| HIS 85 | H.7 | PHE 186 | - | Hydrophobic |
| HIS 85 | H.7 | PHE 186 | - | PiStacking |
| HIS 85 | H.7 | PHE 186 | - | VdWContact |
