Predicted complex interactions
CCL4_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm33 | TYR 94 | 2.63x63 | CationPi |
| ALA 1 | NTc.Cm33 | TYR 94 | 2.63x63 | HBDonor |
| ALA 1 | NTc.Cm33 | TYR 94 | 2.63x63 | VdWContact |
| PRO 2 | NTc.Cm32 | TYR 42 | 1.39x39 | Hydrophobic |
| PRO 2 | NTc.Cm32 | TYR 42 | 1.39x39 | VdWContact |
| PRO 2 | NTc.Cm32 | GLN 91 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm32 | HIS 283 | 7.36x35 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 286 | 7.39x38 | VdWContact |
| MET 3 | NTc.Cm31 | TYR 94 | 2.63x63 | Hydrophobic |
| MET 3 | NTc.Cm31 | TRP 99 | 23.50x50 | Hydrophobic |
| MET 3 | NTc.Cm31 | TYR 113 | 3.32x32 | Hydrophobic |
| MET 3 | NTc.Cm31 | TYR 172 | 4.64x65 | HBAcceptor |
| MET 3 | NTc.Cm31 | TYR 172 | 4.64x65 | Hydrophobic |
| MET 3 | NTc.Cm31 | TYR 172 | 4.64x65 | VdWContact |
| MET 3 | NTc.Cm31 | CYS 183 | 45.50x50 | Hydrophobic |
| MET 3 | NTc.Cm31 | CYS 183 | 45.50x50 | VdWContact |
| GLY 4 | NTc.Cm30 | GLU 286 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm30 | GLU 286 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm29 | THR 282 | 7.35x34 | VdWContact |
| SER 5 | NTc.Cm29 | GLU 286 | 7.39x38 | HBDonor |
| SER 5 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| ASP 6 | NTc.Cm28 | TYR 184 | 45.51x51 | HBAcceptor |
| ASP 6 | NTc.Cm28 | TYR 184 | 45.51x51 | VdWContact |
| ASP 6 | NTc.Cm28 | LYS 195 | 5.35x36 | Anionic |
| ASP 6 | NTc.Cm28 | LYS 195 | 5.35x36 | HBAcceptor |
| ASP 6 | NTc.Cm28 | LYS 195 | 5.35x36 | VdWContact |
| PRO 7 | NTc.Cm27 | GLN 182 | - | Hydrophobic |
| PRO 7 | NTc.Cm27 | GLN 182 | - | VdWContact |
| PRO 7 | NTc.Cm27 | TYR 184 | 45.51x51 | Hydrophobic |
| PRO 7 | NTc.Cm27 | TYR 184 | 45.51x51 | VdWContact |
| PRO 7 | NTc.Cm27 | PHE 186 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | GLU 28 | - | Hydrophobic |
| PRO 8 | NTc.Cm26 | GLU 28 | - | VdWContact |
| PRO 8 | NTc.Cm26 | GLN 182 | - | HBAcceptor |
| PRO 8 | NTc.Cm26 | GLN 182 | - | VdWContact |
| ALA 10 | NTc.Cm24 | PRO 24 | - | Hydrophobic |
| ALA 10 | NTc.Cm24 | CYS 25 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 25 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 25 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 25 | - | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 25 | - | Hydrophobic |
| PHE 13 | NTc.Cm21 | CYS 25 | - | VdWContact |
| PHE 13 | NTc.Cm21 | HIS 264 | 6.61x61 | Hydrophobic |
| PHE 13 | NTc.Cm21 | HIS 264 | 6.61x61 | VdWContact |
| PHE 13 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| SER 14 | NTc.Cm20 | PHE 21 | - | HBDonor |
| SER 14 | NTc.Cm20 | PHE 21 | - | VdWContact |
| THR 16 | NTc.Cm18 | PRO 18 | - | VdWContact |
| LYS 19 | NTc.Cm15 | TYR 16 | - | HBAcceptor |
| LYS 19 | NTc.Cm15 | TYR 16 | - | VdWContact |
| LEU 20 | NTc.Cm14 | PRO 18 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TYR 16 | - | Hydrophobic |
| PRO 21 | NTc.Cm13 | TYR 16 | - | VdWContact |
| PHE 24 | NTc.Cm10 | VAL 12 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 16 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | TYR 17 | - | Hydrophobic |
| SER 32 | NTc.Cm2 | GLU 177 | - | HBDonor |
| SER 32 | NTc.Cm2 | GLU 177 | - | VdWContact |
| SER 33 | NTc.Cm1 | GLN 189 | - | VdWContact |
| SER 33 | NTc.Cm1 | THR 191 | 5.31x32 | HBAcceptor |
| SER 33 | NTc.Cm1 | THR 191 | 5.31x32 | VdWContact |
| SER 33 | NTc.Cm1 | LEU 192 | 5.32x33 | HBAcceptor |
| SER 33 | NTc.Cm1 | LEU 192 | 5.32x33 | VdWContact |
| LEU 34 | CX.1 | TYR 184 | 45.51x51 | Hydrophobic |
| LEU 34 | CX.1 | TYR 184 | 45.51x51 | VdWContact |
| LEU 34 | CX.1 | PHE 186 | - | Hydrophobic |
| LEU 34 | CX.1 | THR 191 | 5.31x32 | Hydrophobic |
| LEU 34 | CX.1 | THR 191 | 5.31x32 | VdWContact |
| LEU 34 | CX.1 | LEU 192 | 5.32x33 | VdWContact |
| SER 36 | cxb1.1 | LEU 192 | 5.32x33 | VdWContact |
| SER 36 | cxb1.1 | HIS 267 | 6.64x64 | VdWContact |
| GLN 37 | cxb1.2 | HIS 267 | 6.64x64 | Hydrophobic |
| GLN 37 | cxb1.2 | HIS 267 | 6.64x64 | VdWContact |
| VAL 41 | cxb1.8 | PRO 24 | - | Hydrophobic |
| VAL 41 | cxb1.8 | PRO 24 | - | VdWContact |
| THR 44 | cxb1.14 | TYR 17 | - | Hydrophobic |
| THR 44 | cxb1.14 | TYR 17 | - | VdWContact |
| ARG 46 | cxb1.16 | ASP 14 | - | Cationic |
| ARG 46 | cxb1.16 | ASP 14 | - | HBDonor |
| ARG 46 | cxb1.16 | ASP 14 | - | VdWContact |
| ARG 46 | cxb1.16 | TYR 17 | - | Hydrophobic |
| ARG 46 | cxb1.16 | TYR 17 | - | VdWContact |
| LYS 48 | B1.2 | ASP 14 | - | Cationic |
| LYS 48 | B1.2 | ASP 14 | - | HBDonor |
| LYS 48 | B1.2 | ASP 14 | - | VdWContact |
| LYS 48 | B1.2 | TYR 17 | - | Hydrophobic |
| LYS 48 | B1.2 | TYR 17 | - | VdWContact |
| GLN 49 | B1.3 | PRO 24 | - | Hydrophobic |
| GLN 49 | B1.3 | PRO 24 | - | VdWContact |
| VAL 50 | B1.4 | PRO 18 | - | Hydrophobic |
| VAL 50 | B1.4 | SER 22 | - | VdWContact |
| CYS 51 | B1.5 | SER 22 | - | HBDonor |
| CYS 51 | B1.5 | SER 22 | - | VdWContact |
