Predicted complex interactions
CCL5_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 71
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 1 | NTc.Cm32 | GLN 91 | 2.60x60 | VdWContact |
| SER 1 | NTc.Cm32 | GLU 286 | 7.39x38 | HBDonor |
| SER 1 | NTc.Cm32 | GLU 286 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm31 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 172 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm31 | TYR 172 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm31 | TYR 184 | 45.51x51 | VdWContact |
| TYR 3 | NTc.Cm30 | TYR 113 | 3.32x32 | Hydrophobic |
| TYR 3 | NTc.Cm30 | TYR 114 | 3.33x33 | HBAcceptor |
| TYR 3 | NTc.Cm30 | TYR 114 | 3.33x33 | VdWContact |
| TYR 3 | NTc.Cm30 | THR 198 | 5.38x39 | VdWContact |
| TYR 3 | NTc.Cm30 | ASN 199 | 5.39x40 | VdWContact |
| TYR 3 | NTc.Cm30 | MET 202 | 5.42x43 | Hydrophobic |
| TYR 3 | NTc.Cm30 | MET 202 | 5.42x43 | VdWContact |
| TYR 3 | NTc.Cm30 | PHE 254 | 6.51x51 | Hydrophobic |
| TYR 3 | NTc.Cm30 | LEU 258 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm30 | THR 282 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm30 | THR 282 | 7.35x34 | VdWContact |
| TYR 3 | NTc.Cm30 | GLU 286 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm29 | HIS 283 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| SER 5 | NTc.Cm28 | TYR 94 | 2.63x63 | HBAcceptor |
| ASP 6 | NTc.Cm27 | LYS 195 | 5.35x36 | Anionic |
| ASP 6 | NTc.Cm27 | LYS 195 | 5.35x36 | HBAcceptor |
| ASP 6 | NTc.Cm27 | LYS 195 | 5.35x36 | VdWContact |
| THR 7 | NTc.Cm26 | GLU 28 | - | Hydrophobic |
| THR 7 | NTc.Cm26 | GLU 28 | - | VdWContact |
| PRO 9 | NTc.Cm24 | PRO 24 | - | Hydrophobic |
| PRO 9 | NTc.Cm24 | CYS 25 | - | VdWContact |
| CYS 10 | NTc.Cm23 | CYS 25 | - | HBAcceptor |
| CYS 10 | NTc.Cm23 | CYS 25 | - | HBDonor |
| CYS 10 | NTc.Cm23 | CYS 25 | - | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 25 | - | Hydrophobic |
| PHE 12 | NTc.Cm21 | CYS 25 | - | VdWContact |
| PHE 12 | NTc.Cm21 | HIS 264 | 6.61x61 | Hydrophobic |
| PHE 12 | NTc.Cm21 | HIS 264 | 6.61x61 | VdWContact |
| PHE 12 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| ILE 15 | NTc.Cm18 | ASP 19 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 17 | - | Hydrophobic |
| LEU 19 | NTc.Cm14 | TYR 17 | - | VdWContact |
| PRO 20 | NTc.Cm13 | TYR 15 | - | Hydrophobic |
| PRO 20 | NTc.Cm13 | TYR 17 | - | VdWContact |
| HIS 23 | NTc.Cm10 | TYR 15 | - | Hydrophobic |
| HIS 23 | NTc.Cm10 | TYR 15 | - | PiStacking |
| HIS 23 | NTc.Cm10 | TYR 15 | - | VdWContact |
| HIS 23 | NTc.Cm10 | TYR 17 | - | HBDonor |
| HIS 23 | NTc.Cm10 | TYR 17 | - | Hydrophobic |
| HIS 23 | NTc.Cm10 | TYR 17 | - | VdWContact |
| SER 31 | NTc.Cm2 | GLU 177 | - | HBDonor |
| SER 31 | NTc.Cm2 | GLU 177 | - | VdWContact |
| GLY 32 | NTc.Cm1 | THR 191 | 5.31x32 | VdWContact |
| GLY 32 | NTc.Cm1 | LEU 192 | 5.32x33 | HBAcceptor |
| GLY 32 | NTc.Cm1 | LEU 192 | 5.32x33 | VdWContact |
| LYS 33 | CX.1 | GLN 182 | - | HBDonor |
| LYS 33 | CX.1 | GLN 182 | - | VdWContact |
| LYS 33 | CX.1 | TYR 184 | 45.51x51 | Hydrophobic |
| LYS 33 | CX.1 | PHE 186 | - | Hydrophobic |
| LYS 33 | CX.1 | THR 191 | 5.31x32 | Hydrophobic |
| LYS 33 | CX.1 | THR 191 | 5.31x32 | VdWContact |
| SER 35 | cxb1.1 | LEU 192 | 5.32x33 | VdWContact |
| SER 35 | cxb1.1 | HIS 267 | 6.64x64 | VdWContact |
| ASN 36 | cxb1.2 | HIS 267 | 6.64x64 | VdWContact |
| VAL 40 | cxb1.8 | PRO 24 | - | Hydrophobic |
| THR 43 | cxb1.14 | TYR 17 | - | Hydrophobic |
| LYS 45 | cxb1.16 | ASP 14 | - | Cationic |
| LYS 45 | cxb1.16 | ASP 14 | - | VdWContact |
| GLN 48 | B1.3 | PRO 24 | - | Hydrophobic |
| GLN 48 | B1.3 | PRO 24 | - | VdWContact |
| VAL 49 | B1.4 | SER 22 | - | VdWContact |
| CYS 50 | B1.5 | SER 22 | - | HBDonor |
| CYS 50 | B1.5 | SER 22 | - | VdWContact |
