Predicted complex interactions
CCL7_HUMAN + CCR8
SUMMARY
- Chemokine
- CCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 85
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm33 | GLN 91 | 2.60x60 | HBDonor |
| GLN 1 | NTc.Cm33 | GLN 91 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm33 | SER 110 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 113 | 3.32x32 | HBDonor |
| GLN 1 | NTc.Cm33 | TYR 113 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 113 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 114 | 3.33x33 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 114 | 3.33x33 | VdWContact |
| GLN 1 | NTc.Cm33 | TYR 172 | 4.64x65 | Hydrophobic |
| GLN 1 | NTc.Cm33 | TYR 172 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm33 | GLU 286 | 7.39x38 | Cationic |
| PRO 2 | NTc.Cm32 | GLN 91 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm32 | GLU 286 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm32 | PHE 290 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm32 | PHE 290 | 7.43x42 | VdWContact |
| VAL 3 | NTc.Cm31 | TYR 184 | 45.51x51 | Hydrophobic |
| GLY 4 | NTc.Cm30 | TYR 94 | 2.63x63 | VdWContact |
| ILE 5 | NTc.Cm29 | GLU 28 | - | VdWContact |
| ILE 5 | NTc.Cm29 | LYS 35 | 1.32x32 | HBAcceptor |
| ILE 5 | NTc.Cm29 | LYS 35 | 1.32x32 | Hydrophobic |
| ILE 5 | NTc.Cm29 | LYS 35 | 1.32x32 | VdWContact |
| ILE 5 | NTc.Cm29 | TYR 94 | 2.63x63 | HBDonor |
| ILE 5 | NTc.Cm29 | TYR 94 | 2.63x63 | VdWContact |
| ILE 5 | NTc.Cm29 | LEU 95 | 2.64x64 | VdWContact |
| ILE 5 | NTc.Cm29 | LEU 96 | 2.65x65 | VdWContact |
| ASN 6 | NTc.Cm28 | VAL 180 | - | Hydrophobic |
| ASN 6 | NTc.Cm28 | VAL 180 | - | VdWContact |
| THR 7 | NTc.Cm27 | GLN 182 | - | Hydrophobic |
| THR 7 | NTc.Cm27 | GLN 182 | - | VdWContact |
| THR 9 | NTc.Cm25 | ALA 27 | - | HBAcceptor |
| THR 9 | NTc.Cm25 | ALA 27 | - | VdWContact |
| THR 10 | NTc.Cm24 | PRO 24 | - | Hydrophobic |
| THR 10 | NTc.Cm24 | PRO 24 | - | VdWContact |
| THR 10 | NTc.Cm24 | CYS 25 | - | VdWContact |
| THR 10 | NTc.Cm24 | ASP 26 | - | HBDonor |
| THR 10 | NTc.Cm24 | ASP 26 | - | VdWContact |
| CYS 11 | NTc.Cm23 | CYS 25 | - | HBAcceptor |
| CYS 11 | NTc.Cm23 | CYS 25 | - | HBDonor |
| CYS 11 | NTc.Cm23 | CYS 25 | - | VdWContact |
| TYR 13 | NTc.Cm21 | CYS 25 | - | Hydrophobic |
| TYR 13 | NTc.Cm21 | HIS 264 | 6.61x61 | Hydrophobic |
| TYR 13 | NTc.Cm21 | HIS 264 | 6.61x61 | VdWContact |
| TYR 13 | NTc.Cm21 | ASP 270 | - | VdWContact |
| TYR 13 | NTc.Cm21 | CYS 272 | 7.25x24 | Hydrophobic |
| TYR 13 | NTc.Cm21 | CYS 272 | 7.25x24 | VdWContact |
| TYR 13 | NTc.Cm21 | SER 275 | 7.28x27 | VdWContact |
| ARG 14 | NTc.Cm20 | PHE 21 | - | VdWContact |
| ILE 16 | NTc.Cm18 | PRO 18 | - | Hydrophobic |
| ILE 16 | NTc.Cm18 | PRO 18 | - | VdWContact |
| ARG 24 | NTc.Cm10 | ASP 14 | - | HBDonor |
| ARG 24 | NTc.Cm10 | ASP 14 | - | VdWContact |
| ARG 24 | NTc.Cm10 | TYR 15 | - | CationPi |
| ARG 24 | NTc.Cm10 | TYR 15 | - | VdWContact |
| ARG 29 | NTc.Cm5 | ASP 178 | - | Cationic |
| SER 34 | CX.1 | GLN 189 | - | VdWContact |
| SER 34 | CX.1 | THR 191 | 5.31x32 | VdWContact |
| SER 34 | CX.1 | LEU 192 | 5.32x33 | HBAcceptor |
| SER 34 | CX.1 | LEU 192 | 5.32x33 | VdWContact |
| HIS 35 | CX.5 | GLU 177 | - | Hydrophobic |
| HIS 35 | CX.5 | GLU 177 | - | VdWContact |
| HIS 35 | CX.5 | PHE 186 | - | Hydrophobic |
| HIS 35 | CX.5 | PHE 186 | - | VdWContact |
| HIS 35 | CX.5 | THR 191 | 5.31x32 | Hydrophobic |
| PRO 37 | cxb1.2 | HIS 264 | 6.61x61 | Hydrophobic |
| PRO 37 | cxb1.2 | HIS 267 | 6.64x64 | Hydrophobic |
| PRO 37 | cxb1.2 | HIS 267 | 6.64x64 | VdWContact |
| ARG 38 | cxb1.5 | HIS 267 | 6.64x64 | Hydrophobic |
| ARG 38 | cxb1.5 | HIS 267 | 6.64x64 | VdWContact |
| ARG 38 | cxb1.5 | ASP 270 | - | Cationic |
| ARG 38 | cxb1.5 | ASP 270 | - | HBDonor |
| ARG 38 | cxb1.5 | ASP 270 | - | VdWContact |
| ILE 42 | cxb1.10 | PRO 24 | - | Hydrophobic |
| LEU 47 | B1.1 | TYR 15 | - | Hydrophobic |
| LEU 47 | B1.1 | TYR 17 | - | Hydrophobic |
| LEU 47 | B1.1 | TYR 17 | - | VdWContact |
| LYS 49 | B1.3 | TYR 17 | - | CationPi |
| LYS 49 | B1.3 | TYR 17 | - | Hydrophobic |
| LYS 49 | B1.3 | TYR 17 | - | VdWContact |
| GLU 50 | B1.4 | PRO 24 | - | Hydrophobic |
| GLU 50 | B1.4 | PRO 24 | - | VdWContact |
| ILE 51 | B1.5 | PRO 18 | - | Hydrophobic |
| ILE 51 | B1.5 | PRO 18 | - | VdWContact |
| CYS 52 | B1.6 | SER 22 | - | HBDonor |
| CYS 52 | B1.6 | SER 22 | - | VdWContact |
| CYS 52 | B1.6 | PRO 24 | - | VdWContact |
