Predicted complex interactions
CX3CL1_HUMAN + CCR8
SUMMARY
- Chemokine
- CX3CL1_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm37 | TYR 94 | 2.63x63 | Hydrophobic |
| GLN 1 | NTc.Cm37 | TYR 94 | 2.63x63 | VdWContact |
| GLN 1 | NTc.Cm37 | SER 110 | 3.29x29 | VdWContact |
| GLN 1 | NTc.Cm37 | TYR 172 | 4.64x65 | HBDonor |
| GLN 1 | NTc.Cm37 | TYR 172 | 4.64x65 | Hydrophobic |
| GLN 1 | NTc.Cm37 | TYR 172 | 4.64x65 | VdWContact |
| GLN 1 | NTc.Cm37 | CYS 183 | 45.50x50 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 42 | 1.39x39 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLN 91 | 2.60x60 | HBDonor |
| HIS 2 | NTc.Cm36 | GLN 91 | 2.60x60 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLN 91 | 2.60x60 | VdWContact |
| HIS 2 | NTc.Cm36 | TYR 113 | 3.32x32 | Hydrophobic |
| HIS 2 | NTc.Cm36 | GLU 286 | 7.39x38 | VdWContact |
| HIS 2 | NTc.Cm36 | PHE 290 | 7.43x42 | Hydrophobic |
| HIS 3 | NTc.Cm35 | ASN 199 | 5.39x40 | HBDonor |
| HIS 3 | NTc.Cm35 | ASN 199 | 5.39x40 | VdWContact |
| HIS 3 | NTc.Cm35 | MET 202 | 5.42x43 | Hydrophobic |
| HIS 3 | NTc.Cm35 | MET 202 | 5.42x43 | VdWContact |
| HIS 3 | NTc.Cm35 | LEU 258 | 6.55x55 | Hydrophobic |
| HIS 3 | NTc.Cm35 | LEU 258 | 6.55x55 | VdWContact |
| HIS 3 | NTc.Cm35 | THR 282 | 7.35x34 | Hydrophobic |
| HIS 3 | NTc.Cm35 | THR 282 | 7.35x34 | VdWContact |
| HIS 3 | NTc.Cm35 | GLU 286 | 7.39x38 | HBDonor |
| HIS 3 | NTc.Cm35 | GLU 286 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm34 | HIS 283 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm34 | GLU 286 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm34 | GLU 286 | 7.39x38 | VdWContact |
| VAL 5 | NTc.Cm33 | TYR 94 | 2.63x63 | HBAcceptor |
| VAL 5 | NTc.Cm33 | TYR 94 | 2.63x63 | Hydrophobic |
| VAL 5 | NTc.Cm33 | TYR 94 | 2.63x63 | VdWContact |
| VAL 5 | NTc.Cm33 | LEU 95 | 2.64x64 | Hydrophobic |
| LYS 7 | NTc.Cm31 | TYR 94 | 2.63x63 | VdWContact |
| LYS 7 | NTc.Cm31 | ASP 97 | 2.66x66 | VdWContact |
| LYS 7 | NTc.Cm31 | VAL 180 | - | Hydrophobic |
| LYS 7 | NTc.Cm31 | GLN 182 | - | HBAcceptor |
| LYS 7 | NTc.Cm31 | GLN 182 | - | HBDonor |
| LYS 7 | NTc.Cm31 | GLN 182 | - | VdWContact |
| ASN 9 | NTc.Cm29 | ASP 26 | - | VdWContact |
| ASN 9 | NTc.Cm29 | ALA 27 | - | HBAcceptor |
| ASN 9 | NTc.Cm29 | ALA 27 | - | VdWContact |
| ILE 10 | NTc.Cm28 | PRO 24 | - | Hydrophobic |
| ILE 10 | NTc.Cm28 | PRO 24 | - | VdWContact |
| ILE 10 | NTc.Cm28 | CYS 25 | - | VdWContact |
| THR 11 | NTc.Cm27 | CYS 25 | - | HBAcceptor |
| THR 11 | NTc.Cm27 | CYS 25 | - | HBDonor |
| THR 11 | NTc.Cm27 | CYS 25 | - | VdWContact |
| THR 11 | NTc.Cm27 | ALA 27 | - | Hydrophobic |
| THR 11 | NTc.Cm27 | ALA 27 | - | VdWContact |
| SER 13 | NTc.Cm25 | HIS 267 | 6.64x64 | VdWContact |
| LYS 14 | NTc.Cm24 | ASP 19 | - | Cationic |
| LYS 14 | NTc.Cm24 | ASP 19 | - | HBDonor |
| LYS 14 | NTc.Cm24 | ASP 19 | - | VdWContact |
| LYS 14 | NTc.Cm24 | PHE 21 | - | Hydrophobic |
| LYS 14 | NTc.Cm24 | PHE 21 | - | VdWContact |
| THR 16 | NTc.Cm22 | PRO 18 | - | VdWContact |
| THR 16 | NTc.Cm22 | SER 22 | - | HBDonor |
| THR 16 | NTc.Cm22 | SER 22 | - | VdWContact |
| LYS 18 | NTc.Cm20 | TYR 16 | - | VdWContact |
| ILE 19 | NTc.Cm19 | PRO 18 | - | Hydrophobic |
| ILE 19 | NTc.Cm19 | PRO 18 | - | VdWContact |
| PRO 20 | NTc.Cm18 | VAL 12 | - | Hydrophobic |
| PRO 20 | NTc.Cm18 | TYR 16 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | VAL 12 | - | Hydrophobic |
| LEU 23 | NTc.Cm15 | VAL 12 | - | VdWContact |
| GLN 31 | NTc.Cm7 | GLU 177 | - | Hydrophobic |
| GLN 31 | NTc.Cm7 | GLU 177 | - | VdWContact |
| GLN 31 | NTc.Cm7 | ASP 178 | - | HBDonor |
| GLN 31 | NTc.Cm7 | ASP 178 | - | VdWContact |
| ALA 32 | NTc.Cm6 | GLU 177 | - | HBDonor |
| ALA 32 | NTc.Cm6 | GLU 177 | - | VdWContact |
| ALA 32 | NTc.Cm6 | TYR 184 | 45.51x51 | Hydrophobic |
| ALA 32 | NTc.Cm6 | TYR 184 | 45.51x51 | VdWContact |
| ALA 32 | NTc.Cm6 | PHE 186 | - | Hydrophobic |
| ALA 32 | NTc.Cm6 | PHE 186 | - | VdWContact |
| SER 33 | NTc.Cm5 | GLU 177 | - | HBDonor |
| SER 33 | NTc.Cm5 | GLU 177 | - | VdWContact |
| SER 33 | NTc.Cm5 | TYR 184 | 45.51x51 | VdWContact |
| GLY 35 | NTc.Cm3 | THR 191 | 5.31x32 | VdWContact |
| GLY 35 | NTc.Cm3 | LEU 192 | 5.32x33 | HBAcceptor |
| GLY 35 | NTc.Cm3 | LEU 192 | 5.32x33 | VdWContact |
| LYS 36 | NTc.Cm2 | LEU 192 | 5.32x33 | Hydrophobic |
| LYS 36 | NTc.Cm2 | HIS 267 | 6.64x64 | HBDonor |
| LYS 36 | NTc.Cm2 | HIS 267 | 6.64x64 | VdWContact |
| ARG 37 | NTc.Cm1 | GLN 189 | - | VdWContact |
| ILE 40 | CX.3 | PRO 24 | - | Hydrophobic |
| THR 43 | cxb1.1 | TYR 17 | - | Hydrophobic |
| THR 43 | cxb1.1 | TYR 17 | - | VdWContact |
| GLN 45 | cxb1.5 | ASP 14 | - | VdWContact |
| GLN 45 | cxb1.5 | TYR 17 | - | Hydrophobic |
| GLN 45 | cxb1.5 | TYR 17 | - | VdWContact |
| ARG 47 | cxb1.8 | TYR 17 | - | CationPi |
| ARG 47 | cxb1.8 | TYR 17 | - | Hydrophobic |
| ARG 47 | cxb1.8 | TYR 17 | - | VdWContact |
| LEU 48 | cxb1.10 | SER 23 | - | VdWContact |
| LEU 48 | cxb1.10 | PRO 24 | - | Hydrophobic |
| LEU 48 | cxb1.10 | PRO 24 | - | VdWContact |
| PHE 49 | cxb1.11 | TYR 17 | - | Hydrophobic |
| PHE 49 | cxb1.11 | TYR 17 | - | VdWContact |
| PHE 49 | cxb1.11 | PRO 18 | - | Hydrophobic |
| PHE 49 | cxb1.11 | SER 22 | - | VdWContact |
| CYS 50 | cxb1.14 | SER 22 | - | HBDonor |
| CYS 50 | cxb1.14 | SER 22 | - | VdWContact |
| CYS 50 | cxb1.14 | PRO 24 | - | VdWContact |
