Predicted complex interactions
CXCL10_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL10_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 81
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm29 | TYR 94 | 2.63x63 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 113 | 3.32x32 | CationPi |
| VAL 1 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm29 | TYR 172 | 4.64x65 | Hydrophobic |
| VAL 1 | NTc.Cm29 | TYR 172 | 4.64x65 | VdWContact |
| PRO 2 | NTc.Cm28 | TYR 94 | 2.63x63 | Hydrophobic |
| PRO 2 | NTc.Cm28 | GLU 286 | 7.39x38 | VdWContact |
| LEU 3 | NTc.Cm27 | TYR 114 | 3.33x33 | Hydrophobic |
| LEU 3 | NTc.Cm27 | TYR 114 | 3.33x33 | VdWContact |
| LEU 3 | NTc.Cm27 | THR 198 | 5.38x39 | Hydrophobic |
| LEU 3 | NTc.Cm27 | MET 202 | 5.42x43 | Hydrophobic |
| LEU 3 | NTc.Cm27 | MET 202 | 5.42x43 | VdWContact |
| LEU 3 | NTc.Cm27 | PHE 254 | 6.51x51 | Hydrophobic |
| LEU 3 | NTc.Cm27 | PHE 254 | 6.51x51 | VdWContact |
| LEU 3 | NTc.Cm27 | LEU 258 | 6.55x55 | Hydrophobic |
| SER 4 | NTc.Cm26 | HIS 283 | 7.36x35 | HBDonor |
| SER 4 | NTc.Cm26 | HIS 283 | 7.36x35 | VdWContact |
| ARG 5 | NTc.Cm25 | TYR 94 | 2.63x63 | CationPi |
| ARG 5 | NTc.Cm25 | TYR 94 | 2.63x63 | VdWContact |
| ARG 5 | NTc.Cm25 | GLN 182 | - | VdWContact |
| THR 6 | NTc.Cm24 | ALA 27 | - | Hydrophobic |
| THR 6 | NTc.Cm24 | THR 279 | 7.32x31 | Hydrophobic |
| THR 6 | NTc.Cm24 | THR 279 | 7.32x31 | VdWContact |
| VAL 7 | NTc.Cm23 | TYR 184 | 45.51x51 | Hydrophobic |
| VAL 7 | NTc.Cm23 | THR 191 | 5.31x32 | Hydrophobic |
| VAL 7 | NTc.Cm23 | THR 191 | 5.31x32 | VdWContact |
| ARG 8 | NTc.Cm22 | ALA 27 | - | Hydrophobic |
| ARG 8 | NTc.Cm22 | SER 275 | 7.28x27 | HBDonor |
| ARG 8 | NTc.Cm22 | SER 275 | 7.28x27 | VdWContact |
| THR 10 | NTc.Cm20 | CYS 25 | - | HBAcceptor |
| THR 10 | NTc.Cm20 | CYS 25 | - | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 25 | - | Hydrophobic |
| ILE 12 | NTc.Cm18 | GLY 271 | 7.24x23 | VdWContact |
| ILE 12 | NTc.Cm18 | CYS 272 | 7.25x24 | Hydrophobic |
| ILE 12 | NTc.Cm18 | CYS 272 | 7.25x24 | VdWContact |
| SER 13 | NTc.Cm17 | PHE 21 | - | HBDonor |
| SER 13 | NTc.Cm17 | PHE 21 | - | VdWContact |
| ASN 20 | NTc.Cm10 | VAL 12 | - | Hydrophobic |
| ASN 20 | NTc.Cm10 | VAL 12 | - | VdWContact |
| PRO 21 | NTc.Cm9 | LEU 7 | - | Hydrophobic |
| PRO 21 | NTc.Cm9 | LEU 7 | - | VdWContact |
| ARG 22 | NTc.Cm8 | SER 8 | - | VdWContact |
| ARG 22 | NTc.Cm8 | VAL 9 | - | HBDonor |
| ARG 22 | NTc.Cm8 | VAL 9 | - | VdWContact |
| ARG 22 | NTc.Cm8 | THR 10 | - | HBDonor |
| ARG 22 | NTc.Cm8 | THR 10 | - | VdWContact |
| SER 23 | NTc.Cm7 | ASP 14 | - | HBDonor |
| SER 23 | NTc.Cm7 | ASP 14 | - | VdWContact |
| LEU 24 | NTc.Cm6 | LEU 7 | - | Hydrophobic |
| LYS 26 | NTc.Cm4 | ASP 2 | - | Cationic |
| LYS 26 | NTc.Cm4 | ASP 2 | - | HBDonor |
| LYS 26 | NTc.Cm4 | ASP 2 | - | VdWContact |
| GLN 34 | cxb1.2 | ALA 175 | - | VdWContact |
| GLN 34 | cxb1.2 | PHE 186 | - | Hydrophobic |
| GLN 34 | cxb1.2 | PHE 186 | - | VdWContact |
| GLN 34 | cxb1.2 | GLN 189 | - | Hydrophobic |
| GLN 34 | cxb1.2 | THR 191 | 5.31x32 | HBAcceptor |
| GLN 34 | cxb1.2 | THR 191 | 5.31x32 | VdWContact |
| PHE 35 | cxb1.5 | GLU 177 | - | Hydrophobic |
| PHE 35 | cxb1.5 | GLU 177 | - | VdWContact |
| PHE 35 | cxb1.5 | GLN 182 | - | Hydrophobic |
| PHE 35 | cxb1.5 | GLN 182 | - | VdWContact |
| PHE 35 | cxb1.5 | PHE 186 | - | Hydrophobic |
| PHE 35 | cxb1.5 | PHE 186 | - | VdWContact |
| ILE 42 | cxb1.15 | PRO 24 | - | Hydrophobic |
| ILE 42 | cxb1.15 | PRO 24 | - | VdWContact |
| LYS 51 | b1b2.4 | SER 23 | - | VdWContact |
| LYS 51 | b1b2.4 | PRO 24 | - | Hydrophobic |
| ARG 52 | b1b2.6 | ASP 19 | - | Cationic |
| ARG 52 | b1b2.6 | ASP 19 | - | HBDonor |
| ARG 52 | b1b2.6 | ASP 19 | - | VdWContact |
| ARG 52 | b1b2.6 | SER 22 | - | VdWContact |
| CYS 53 | b1b2.7 | SER 22 | - | HBDonor |
| CYS 53 | b1b2.7 | SER 22 | - | VdWContact |
| VAL 68 | b2b3.3 | LEU 5 | - | Hydrophobic |
| VAL 68 | b2b3.3 | LEU 5 | - | VdWContact |
| ARG 72 | B3.1 | TYR 3 | - | CationPi |
| ARG 72 | B3.1 | TYR 3 | - | VdWContact |
| ARG 75 | B3.4 | ASP 6 | - | Cationic |
| ARG 75 | B3.4 | ASP 6 | - | HBDonor |
| ARG 75 | B3.4 | ASP 6 | - | VdWContact |
