Predicted complex interactions
CXCL13_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL13_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 126
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm32 | TYR 42 | 1.39x39 | Hydrophobic |
| VAL 1 | NTc.Cm32 | TYR 42 | 1.39x39 | VdWContact |
| VAL 1 | NTc.Cm32 | HIS 283 | 7.36x35 | Hydrophobic |
| VAL 1 | NTc.Cm32 | GLU 286 | 7.39x38 | Hydrophobic |
| VAL 1 | NTc.Cm32 | GLU 286 | 7.39x38 | VdWContact |
| VAL 1 | NTc.Cm32 | PHE 290 | 7.43x42 | Hydrophobic |
| LEU 2 | NTc.Cm31 | GLN 91 | 2.60x60 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 113 | 3.32x32 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 113 | 3.32x32 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 172 | 4.64x65 | Hydrophobic |
| LEU 2 | NTc.Cm31 | TYR 172 | 4.64x65 | VdWContact |
| LEU 2 | NTc.Cm31 | TYR 184 | 45.51x51 | VdWContact |
| GLU 3 | NTc.Cm30 | TYR 114 | 3.33x33 | HBAcceptor |
| GLU 3 | NTc.Cm30 | TYR 114 | 3.33x33 | VdWContact |
| GLU 3 | NTc.Cm30 | TYR 172 | 4.64x65 | VdWContact |
| GLU 3 | NTc.Cm30 | TYR 184 | 45.51x51 | VdWContact |
| GLU 3 | NTc.Cm30 | MET 202 | 5.42x43 | Hydrophobic |
| GLU 3 | NTc.Cm30 | MET 202 | 5.42x43 | VdWContact |
| GLU 3 | NTc.Cm30 | LEU 258 | 6.55x55 | Hydrophobic |
| VAL 4 | NTc.Cm29 | THR 279 | 7.32x31 | Hydrophobic |
| VAL 4 | NTc.Cm29 | THR 282 | 7.35x34 | Hydrophobic |
| VAL 4 | NTc.Cm29 | THR 282 | 7.35x34 | VdWContact |
| VAL 4 | NTc.Cm29 | HIS 283 | 7.36x35 | Hydrophobic |
| VAL 4 | NTc.Cm29 | HIS 283 | 7.36x35 | VdWContact |
| VAL 4 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| TYR 5 | NTc.Cm28 | TYR 94 | 2.63x63 | Hydrophobic |
| TYR 5 | NTc.Cm28 | TYR 94 | 2.63x63 | PiStacking |
| TYR 5 | NTc.Cm28 | TYR 94 | 2.63x63 | VdWContact |
| TYR 6 | NTc.Cm27 | TYR 184 | 45.51x51 | Hydrophobic |
| TYR 6 | NTc.Cm27 | TYR 184 | 45.51x51 | VdWContact |
| TYR 6 | NTc.Cm27 | PHE 186 | - | Hydrophobic |
| TYR 6 | NTc.Cm27 | PHE 186 | - | PiStacking |
| TYR 6 | NTc.Cm27 | PHE 186 | - | VdWContact |
| TYR 6 | NTc.Cm27 | THR 191 | 5.31x32 | HBAcceptor |
| TYR 6 | NTc.Cm27 | THR 191 | 5.31x32 | Hydrophobic |
| TYR 6 | NTc.Cm27 | THR 191 | 5.31x32 | VdWContact |
| TYR 6 | NTc.Cm27 | LYS 195 | 5.35x36 | HBAcceptor |
| TYR 6 | NTc.Cm27 | LYS 195 | 5.35x36 | Hydrophobic |
| TYR 6 | NTc.Cm27 | LYS 195 | 5.35x36 | VdWContact |
| THR 7 | NTc.Cm26 | THR 261 | 6.58x58 | Hydrophobic |
| THR 7 | NTc.Cm26 | THR 279 | 7.32x31 | HBDonor |
| THR 7 | NTc.Cm26 | THR 279 | 7.32x31 | VdWContact |
| SER 8 | NTc.Cm25 | ALA 27 | - | VdWContact |
| LEU 9 | NTc.Cm24 | GLU 177 | - | Hydrophobic |
| LEU 9 | NTc.Cm24 | GLN 182 | - | VdWContact |
| LEU 9 | NTc.Cm24 | PHE 186 | - | Hydrophobic |
| ARG 10 | NTc.Cm23 | THR 261 | 6.58x58 | HBDonor |
| ARG 10 | NTc.Cm23 | THR 261 | 6.58x58 | VdWContact |
| ARG 10 | NTc.Cm23 | HIS 264 | 6.61x61 | CationPi |
| ARG 10 | NTc.Cm23 | HIS 264 | 6.61x61 | HBDonor |
| ARG 10 | NTc.Cm23 | HIS 264 | 6.61x61 | VdWContact |
| ARG 10 | NTc.Cm23 | SER 275 | 7.28x27 | HBDonor |
| ARG 10 | NTc.Cm23 | SER 275 | 7.28x27 | VdWContact |
| ARG 12 | NTc.Cm21 | PRO 24 | - | Hydrophobic |
| ARG 12 | NTc.Cm21 | PRO 24 | - | VdWContact |
| ARG 12 | NTc.Cm21 | CYS 25 | - | HBAcceptor |
| ARG 12 | NTc.Cm21 | CYS 25 | - | VdWContact |
| ARG 12 | NTc.Cm21 | ASP 26 | - | Cationic |
| ARG 12 | NTc.Cm21 | ASP 26 | - | HBDonor |
| ARG 12 | NTc.Cm21 | ASP 26 | - | VdWContact |
| ARG 12 | NTc.Cm21 | ASP 178 | - | Cationic |
| ARG 12 | NTc.Cm21 | ASP 178 | - | HBDonor |
| ARG 12 | NTc.Cm21 | ASP 178 | - | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 25 | - | Hydrophobic |
| VAL 14 | NTc.Cm19 | GLY 271 | 7.24x23 | VdWContact |
| VAL 14 | NTc.Cm19 | CYS 272 | 7.25x24 | Hydrophobic |
| GLN 15 | NTc.Cm18 | PHE 21 | - | VdWContact |
| SER 17 | NTc.Cm16 | ASP 19 | - | HBDonor |
| SER 17 | NTc.Cm16 | ASP 19 | - | VdWContact |
| SER 17 | NTc.Cm16 | SER 22 | - | VdWContact |
| ARG 23 | NTc.Cm10 | LEU 5 | - | Hydrophobic |
| ARG 23 | NTc.Cm10 | LEU 5 | - | VdWContact |
| ARG 23 | NTc.Cm10 | LEU 7 | - | Hydrophobic |
| ARG 23 | NTc.Cm10 | LEU 7 | - | VdWContact |
| ARG 24 | NTc.Cm9 | THR 10 | - | HBDonor |
| ARG 24 | NTc.Cm9 | THR 10 | - | VdWContact |
| ARG 24 | NTc.Cm9 | VAL 12 | - | VdWContact |
| PHE 25 | NTc.Cm8 | VAL 12 | - | VdWContact |
| PHE 25 | NTc.Cm8 | ASP 14 | - | Hydrophobic |
| PHE 25 | NTc.Cm8 | ASP 14 | - | VdWContact |
| ILE 26 | NTc.Cm7 | LEU 5 | - | Hydrophobic |
| ASP 27 | NTc.Cm6 | LEU 5 | - | HBAcceptor |
| ASP 27 | NTc.Cm6 | LEU 5 | - | VdWContact |
| ARG 28 | NTc.Cm5 | TYR 3 | - | VdWContact |
| ARG 28 | NTc.Cm5 | THR 4 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | ASP 2 | - | VdWContact |
| ILE 29 | NTc.Cm4 | TYR 3 | - | HBAcceptor |
| ILE 29 | NTc.Cm4 | TYR 3 | - | HBDonor |
| ILE 29 | NTc.Cm4 | TYR 3 | - | VdWContact |
| ILE 29 | NTc.Cm4 | LEU 5 | - | Hydrophobic |
| ILE 29 | NTc.Cm4 | LEU 5 | - | VdWContact |
| GLN 30 | NTc.Cm3 | MET 1 | - | VdWContact |
| GLN 30 | NTc.Cm3 | ASP 2 | - | HBDonor |
| GLN 30 | NTc.Cm3 | ASP 2 | - | VdWContact |
| ILE 31 | NTc.Cm2 | MET 1 | - | HBAcceptor |
| ILE 31 | NTc.Cm2 | MET 1 | - | HBDonor |
| ILE 31 | NTc.Cm2 | MET 1 | - | VdWContact |
| ILE 31 | NTc.Cm2 | TYR 3 | - | Hydrophobic |
| ASN 36 | cxb1.1 | GLU 177 | - | HBDonor |
| ASN 36 | cxb1.1 | GLU 177 | - | VdWContact |
| ASN 36 | cxb1.1 | PHE 186 | - | Hydrophobic |
| ASN 36 | cxb1.1 | PHE 186 | - | VdWContact |
| ASN 36 | cxb1.1 | GLN 189 | - | VdWContact |
| ASN 36 | cxb1.1 | THR 191 | 5.31x32 | VdWContact |
| GLY 37 | cxb1.2 | GLU 177 | - | HBDonor |
| GLY 37 | cxb1.2 | GLU 177 | - | VdWContact |
| PRO 39 | cxb1.6 | LEU 192 | 5.32x33 | Hydrophobic |
| ILE 44 | cxb1.14 | PRO 24 | - | Hydrophobic |
| LYS 47 | B1.1 | ASP 19 | - | Cationic |
| LYS 47 | B1.1 | ASP 19 | - | VdWContact |
| ASN 49 | B1.3 | TYR 16 | - | Hydrophobic |
| ASN 49 | B1.3 | TYR 16 | - | VdWContact |
| ILE 52 | B1.6 | SER 23 | - | VdWContact |
| ILE 52 | B1.6 | PRO 24 | - | Hydrophobic |
| ILE 52 | B1.6 | PRO 24 | - | VdWContact |
| VAL 53 | B1.7 | ASP 19 | - | Hydrophobic |
| VAL 53 | B1.7 | ASP 19 | - | VdWContact |
| VAL 53 | B1.7 | SER 22 | - | VdWContact |
| CYS 54 | b1b2.4 | SER 22 | - | HBDonor |
| CYS 54 | b1b2.4 | SER 22 | - | VdWContact |
| MET 65 | B2.2 | LEU 5 | - | Hydrophobic |
| MET 66 | B2.3 | TYR 3 | - | Hydrophobic |
| MET 66 | B2.3 | TYR 3 | - | VdWContact |
| LEU 69 | B2.6 | TYR 3 | - | Hydrophobic |
| LEU 69 | B2.6 | LEU 5 | - | Hydrophobic |
| LEU 69 | B2.6 | LEU 5 | - | VdWContact |
