Predicted complex interactions
CXCL3_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL3_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 64
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm42 | TYR 113 | 3.32x32 | CationPi |
| ALA 1 | NTc.Cm42 | TYR 113 | 3.32x32 | Hydrophobic |
| ALA 1 | NTc.Cm42 | TYR 113 | 3.32x32 | VdWContact |
| SER 2 | NTc.Cm41 | GLU 286 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm40 | THR 282 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm40 | THR 282 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm40 | HIS 283 | 7.36x35 | VdWContact |
| VAL 3 | NTc.Cm40 | GLU 286 | 7.39x38 | HBDonor |
| VAL 3 | NTc.Cm40 | GLU 286 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm39 | TYR 94 | 2.63x63 | Hydrophobic |
| VAL 4 | NTc.Cm39 | TYR 94 | 2.63x63 | VdWContact |
| THR 5 | NTc.Cm38 | GLU 28 | - | Hydrophobic |
| THR 5 | NTc.Cm38 | GLU 28 | - | VdWContact |
| GLU 6 | NTc.Cm37 | LYS 195 | 5.35x36 | Anionic |
| GLU 6 | NTc.Cm37 | LYS 195 | 5.35x36 | HBAcceptor |
| GLU 6 | NTc.Cm37 | LYS 195 | 5.35x36 | VdWContact |
| LEU 7 | NTc.Cm36 | GLU 177 | - | VdWContact |
| LEU 7 | NTc.Cm36 | GLN 182 | - | VdWContact |
| ARG 8 | NTc.Cm35 | THR 261 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm35 | HIS 264 | 6.61x61 | CationPi |
| ARG 8 | NTc.Cm35 | HIS 264 | 6.61x61 | HBDonor |
| ARG 8 | NTc.Cm35 | HIS 264 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm35 | SER 275 | 7.28x27 | VdWContact |
| ARG 8 | NTc.Cm35 | LEU 278 | 7.31x30 | VdWContact |
| GLN 10 | NTc.Cm33 | PRO 24 | - | Hydrophobic |
| GLN 10 | NTc.Cm33 | PRO 24 | - | VdWContact |
| GLN 10 | NTc.Cm33 | CYS 25 | - | HBAcceptor |
| GLN 10 | NTc.Cm33 | CYS 25 | - | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 25 | - | Hydrophobic |
| LEU 12 | NTc.Cm31 | HIS 264 | 6.61x61 | Hydrophobic |
| LEU 12 | NTc.Cm31 | GLY 271 | 7.24x23 | VdWContact |
| LEU 12 | NTc.Cm31 | CYS 272 | 7.25x24 | Hydrophobic |
| GLN 13 | NTc.Cm30 | PHE 21 | - | VdWContact |
| LEU 15 | NTc.Cm28 | PRO 18 | - | Hydrophobic |
| LEU 15 | NTc.Cm28 | PRO 18 | - | VdWContact |
| LEU 15 | NTc.Cm28 | SER 22 | - | VdWContact |
| ILE 18 | NTc.Cm25 | PRO 18 | - | Hydrophobic |
| ARG 29 | NTc.Cm14 | ASP 178 | - | Cationic |
| ARG 29 | NTc.Cm14 | ASP 178 | - | HBDonor |
| ARG 29 | NTc.Cm14 | ASP 178 | - | VdWContact |
| PRO 33 | NTc.Cm10 | GLU 177 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | GLU 177 | - | VdWContact |
| PRO 33 | NTc.Cm10 | PHE 186 | - | Hydrophobic |
| PRO 33 | NTc.Cm10 | PHE 186 | - | VdWContact |
| PRO 33 | NTc.Cm10 | THR 191 | 5.31x32 | Hydrophobic |
| PRO 33 | NTc.Cm10 | THR 191 | 5.31x32 | VdWContact |
| HIS 34 | NTc.Cm9 | GLU 177 | - | HBDonor |
| HIS 34 | NTc.Cm9 | GLU 177 | - | Hydrophobic |
| HIS 34 | NTc.Cm9 | GLU 177 | - | VdWContact |
| HIS 34 | NTc.Cm9 | GLN 182 | - | HBDonor |
| HIS 34 | NTc.Cm9 | GLN 182 | - | VdWContact |
| HIS 34 | NTc.Cm9 | TYR 184 | 45.51x51 | Hydrophobic |
| HIS 34 | NTc.Cm9 | PHE 186 | - | Hydrophobic |
| ILE 41 | NTc.Cm2 | PRO 24 | - | Hydrophobic |
| LEU 44 | CX.4 | PRO 18 | - | Hydrophobic |
| LEU 44 | CX.4 | PRO 18 | - | VdWContact |
| ASN 46 | cxb1.1 | TYR 17 | - | VdWContact |
| LYS 49 | cxb1.6 | SER 23 | - | VdWContact |
| LYS 49 | cxb1.6 | PRO 24 | - | Hydrophobic |
| ALA 50 | cxb1.8 | PRO 18 | - | Hydrophobic |
| ALA 50 | cxb1.8 | SER 22 | - | VdWContact |
| CYS 51 | cxb1.10 | SER 22 | - | HBDonor |
| CYS 51 | cxb1.10 | SER 22 | - | VdWContact |
| MET 58 | B1.3 | VAL 12 | - | Hydrophobic |
