Predicted complex interactions
CXCL4_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL4_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 70
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ASP 5 | NTc.Cm36 | HIS 267 | 6.64x64 | Hydrophobic |
| ASP 5 | NTc.Cm36 | HIS 267 | 6.64x64 | VdWContact |
| GLY 6 | NTc.Cm35 | LEU 192 | 5.32x33 | VdWContact |
| GLY 6 | NTc.Cm35 | HIS 267 | 6.64x64 | HBAcceptor |
| GLY 6 | NTc.Cm35 | HIS 267 | 6.64x64 | VdWContact |
| LEU 8 | NTc.Cm33 | LYS 195 | 5.35x36 | Hydrophobic |
| LEU 8 | NTc.Cm33 | LYS 195 | 5.35x36 | VdWContact |
| LEU 8 | NTc.Cm33 | THR 261 | 6.58x58 | Hydrophobic |
| LEU 8 | NTc.Cm33 | THR 261 | 6.58x58 | VdWContact |
| LEU 8 | NTc.Cm33 | HIS 264 | 6.61x61 | Hydrophobic |
| LEU 8 | NTc.Cm33 | HIS 264 | 6.61x61 | VdWContact |
| LEU 8 | NTc.Cm33 | SER 265 | 6.62x62 | VdWContact |
| LEU 8 | NTc.Cm33 | SER 275 | 7.28x27 | HBAcceptor |
| LEU 8 | NTc.Cm33 | SER 275 | 7.28x27 | VdWContact |
| GLN 9 | NTc.Cm32 | LYS 195 | 5.35x36 | VdWContact |
| LEU 11 | NTc.Cm30 | PRO 24 | - | Hydrophobic |
| LEU 11 | NTc.Cm30 | PRO 24 | - | VdWContact |
| LEU 11 | NTc.Cm30 | CYS 25 | - | HBAcceptor |
| LEU 11 | NTc.Cm30 | CYS 25 | - | VdWContact |
| LEU 11 | NTc.Cm30 | ASP 26 | - | Hydrophobic |
| VAL 13 | NTc.Cm28 | CYS 25 | - | Hydrophobic |
| LYS 14 | NTc.Cm27 | SER 22 | - | HBAcceptor |
| LYS 14 | NTc.Cm27 | SER 22 | - | VdWContact |
| THR 16 | NTc.Cm25 | PHE 21 | - | Hydrophobic |
| THR 16 | NTc.Cm25 | PHE 21 | - | VdWContact |
| THR 16 | NTc.Cm25 | SER 22 | - | HBDonor |
| THR 16 | NTc.Cm25 | SER 22 | - | VdWContact |
| GLN 18 | NTc.Cm23 | PHE 21 | - | VdWContact |
| VAL 19 | NTc.Cm22 | PHE 21 | - | Hydrophobic |
| VAL 19 | NTc.Cm22 | PHE 21 | - | VdWContact |
| ARG 20 | NTc.Cm21 | ASP 14 | - | Cationic |
| ARG 20 | NTc.Cm21 | ASP 14 | - | VdWContact |
| ARG 22 | NTc.Cm19 | ASP 14 | - | Cationic |
| ARG 22 | NTc.Cm19 | ASP 14 | - | HBDonor |
| ARG 22 | NTc.Cm19 | ASP 14 | - | VdWContact |
| HIS 23 | NTc.Cm18 | ASP 14 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | ASP 14 | - | VdWContact |
| HIS 23 | NTc.Cm18 | TYR 17 | - | Hydrophobic |
| HIS 23 | NTc.Cm18 | TYR 17 | - | VdWContact |
| PRO 34 | NTc.Cm7 | ALA 175 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | GLU 177 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | GLU 177 | - | VdWContact |
| PRO 34 | NTc.Cm7 | TYR 184 | 45.51x51 | Hydrophobic |
| PRO 34 | NTc.Cm7 | TYR 184 | 45.51x51 | VdWContact |
| PRO 34 | NTc.Cm7 | PHE 186 | - | Hydrophobic |
| PRO 34 | NTc.Cm7 | PHE 186 | - | VdWContact |
| PRO 34 | NTc.Cm7 | THR 191 | 5.31x32 | HBAcceptor |
| PRO 34 | NTc.Cm7 | THR 191 | 5.31x32 | VdWContact |
| HIS 35 | NTc.Cm6 | GLU 177 | - | HBDonor |
| HIS 35 | NTc.Cm6 | GLU 177 | - | VdWContact |
| HIS 35 | NTc.Cm6 | GLN 182 | - | HBDonor |
| HIS 35 | NTc.Cm6 | GLN 182 | - | VdWContact |
| HIS 35 | NTc.Cm6 | TYR 184 | 45.51x51 | Hydrophobic |
| ILE 42 | CX.4 | PRO 24 | - | Hydrophobic |
| ILE 42 | CX.4 | PRO 24 | - | VdWContact |
| LEU 45 | cxb1.2 | TYR 17 | - | Hydrophobic |
| LEU 45 | cxb1.2 | TYR 17 | - | VdWContact |
| ARG 49 | cxb1.10 | ASP 19 | - | Cationic |
| ARG 49 | cxb1.10 | ASP 19 | - | HBDonor |
| ARG 49 | cxb1.10 | ASP 19 | - | VdWContact |
| ARG 49 | cxb1.10 | PHE 21 | - | HBDonor |
| ARG 49 | cxb1.10 | PHE 21 | - | VdWContact |
| LYS 50 | cxb1.11 | SER 23 | - | VdWContact |
| LYS 50 | cxb1.11 | PRO 24 | - | Hydrophobic |
| LYS 50 | cxb1.11 | PRO 24 | - | VdWContact |
| ILE 51 | cxb1.14 | PHE 21 | - | Hydrophobic |
| ILE 51 | cxb1.14 | PHE 21 | - | VdWContact |
| ILE 51 | cxb1.14 | SER 22 | - | VdWContact |
| CYS 52 | cxb1.15 | SER 22 | - | HBDonor |
| CYS 52 | cxb1.15 | SER 22 | - | VdWContact |
