Predicted complex interactions
CXCL5_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL5_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 104
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| ALA 1 | NTc.Cm48 | TYR 94 | 2.63x63 | Hydrophobic |
| ALA 1 | NTc.Cm48 | TRP 99 | 23.50x50 | Hydrophobic |
| ALA 1 | NTc.Cm48 | TYR 172 | 4.64x65 | HBAcceptor |
| ALA 1 | NTc.Cm48 | TYR 172 | 4.64x65 | VdWContact |
| ALA 1 | NTc.Cm48 | CYS 183 | 45.50x50 | Cationic |
| ALA 1 | NTc.Cm48 | CYS 183 | 45.50x50 | Hydrophobic |
| ALA 1 | NTc.Cm48 | CYS 183 | 45.50x50 | VdWContact |
| PRO 3 | NTc.Cm46 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 3 | NTc.Cm46 | TYR 113 | 3.32x32 | VdWContact |
| PRO 3 | NTc.Cm46 | MET 202 | 5.42x43 | Hydrophobic |
| PRO 3 | NTc.Cm46 | MET 202 | 5.42x43 | VdWContact |
| PRO 3 | NTc.Cm46 | PHE 254 | 6.51x51 | Hydrophobic |
| PRO 3 | NTc.Cm46 | LEU 258 | 6.55x55 | Hydrophobic |
| ALA 4 | NTc.Cm45 | THR 282 | 7.35x34 | Hydrophobic |
| ALA 4 | NTc.Cm45 | THR 282 | 7.35x34 | VdWContact |
| ALA 4 | NTc.Cm45 | HIS 283 | 7.36x35 | Hydrophobic |
| ALA 4 | NTc.Cm45 | HIS 283 | 7.36x35 | VdWContact |
| ALA 4 | NTc.Cm45 | GLU 286 | 7.39x38 | HBDonor |
| ALA 4 | NTc.Cm45 | GLU 286 | 7.39x38 | Hydrophobic |
| ALA 4 | NTc.Cm45 | GLU 286 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | TYR 94 | 2.63x63 | Hydrophobic |
| ALA 6 | NTc.Cm43 | TYR 184 | 45.51x51 | Hydrophobic |
| ALA 6 | NTc.Cm43 | TYR 184 | 45.51x51 | VdWContact |
| VAL 7 | NTc.Cm42 | THR 279 | 7.32x31 | Hydrophobic |
| VAL 7 | NTc.Cm42 | THR 279 | 7.32x31 | VdWContact |
| VAL 7 | NTc.Cm42 | THR 282 | 7.35x34 | Hydrophobic |
| LEU 8 | NTc.Cm41 | GLU 28 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | GLU 28 | - | VdWContact |
| LEU 8 | NTc.Cm41 | ILE 30 | - | Hydrophobic |
| LEU 8 | NTc.Cm41 | LEU 95 | 2.64x64 | Hydrophobic |
| LEU 8 | NTc.Cm41 | LEU 95 | 2.64x64 | VdWContact |
| LEU 8 | NTc.Cm41 | HIS 283 | 7.36x35 | Hydrophobic |
| LEU 8 | NTc.Cm41 | HIS 283 | 7.36x35 | VdWContact |
| ARG 9 | NTc.Cm40 | GLU 28 | - | Cationic |
| ARG 9 | NTc.Cm40 | VAL 180 | - | VdWContact |
| ARG 9 | NTc.Cm40 | GLN 182 | - | VdWContact |
| GLU 10 | NTc.Cm39 | LYS 195 | 5.35x36 | Anionic |
| GLU 10 | NTc.Cm39 | LYS 195 | 5.35x36 | HBAcceptor |
| GLU 10 | NTc.Cm39 | LYS 195 | 5.35x36 | VdWContact |
| LEU 11 | NTc.Cm38 | TYR 184 | 45.51x51 | Hydrophobic |
| LEU 11 | NTc.Cm38 | TYR 184 | 45.51x51 | VdWContact |
| LEU 11 | NTc.Cm38 | PHE 186 | - | Hydrophobic |
| LEU 11 | NTc.Cm38 | PHE 186 | - | VdWContact |
| LEU 11 | NTc.Cm38 | THR 191 | 5.31x32 | Hydrophobic |
| LEU 11 | NTc.Cm38 | THR 191 | 5.31x32 | VdWContact |
| ARG 12 | NTc.Cm37 | HIS 264 | 6.61x61 | CationPi |
| ARG 12 | NTc.Cm37 | HIS 264 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm37 | SER 275 | 7.28x27 | VdWContact |
| VAL 14 | NTc.Cm35 | PRO 24 | - | Hydrophobic |
| VAL 14 | NTc.Cm35 | PRO 24 | - | VdWContact |
| VAL 14 | NTc.Cm35 | CYS 25 | - | HBAcceptor |
| VAL 14 | NTc.Cm35 | CYS 25 | - | VdWContact |
| LEU 16 | NTc.Cm33 | CYS 25 | - | Hydrophobic |
| LEU 16 | NTc.Cm33 | CYS 272 | 7.25x24 | Hydrophobic |
| GLN 17 | NTc.Cm32 | SER 22 | - | VdWContact |
| THR 18 | NTc.Cm31 | SER 22 | - | VdWContact |
| THR 19 | NTc.Cm30 | PRO 18 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | PRO 18 | - | VdWContact |
| THR 19 | NTc.Cm30 | PHE 21 | - | Hydrophobic |
| THR 19 | NTc.Cm30 | PHE 21 | - | VdWContact |
| THR 19 | NTc.Cm30 | SER 22 | - | HBAcceptor |
| THR 19 | NTc.Cm30 | SER 22 | - | HBDonor |
| THR 19 | NTc.Cm30 | SER 22 | - | VdWContact |
| GLN 20 | NTc.Cm29 | PRO 18 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 15 | - | VdWContact |
| GLY 21 | NTc.Cm28 | TYR 16 | - | VdWContact |
| VAL 22 | NTc.Cm27 | PHE 21 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | VAL 12 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | VAL 12 | - | VdWContact |
| HIS 23 | NTc.Cm26 | TYR 15 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 17 | - | Hydrophobic |
| HIS 23 | NTc.Cm26 | TYR 17 | - | VdWContact |
| PRO 24 | NTc.Cm25 | LEU 7 | - | Hydrophobic |
| PRO 24 | NTc.Cm25 | LEU 7 | - | VdWContact |
| PRO 24 | NTc.Cm25 | VAL 12 | - | VdWContact |
| MET 26 | NTc.Cm23 | TYR 17 | - | Hydrophobic |
| MET 26 | NTc.Cm23 | TYR 17 | - | VdWContact |
| ASN 29 | NTc.Cm20 | ASP 2 | - | HBDonor |
| ASN 29 | NTc.Cm20 | ASP 2 | - | VdWContact |
| LEU 30 | NTc.Cm19 | LEU 5 | - | Hydrophobic |
| LEU 30 | NTc.Cm19 | LEU 5 | - | VdWContact |
| GLN 31 | NTc.Cm18 | ASP 2 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLU 177 | - | VdWContact |
| PRO 37 | NTc.Cm12 | PHE 186 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | PHE 186 | - | VdWContact |
| PRO 37 | NTc.Cm12 | GLN 189 | - | Hydrophobic |
| PRO 37 | NTc.Cm12 | THR 191 | 5.31x32 | HBAcceptor |
| PRO 37 | NTc.Cm12 | THR 191 | 5.31x32 | VdWContact |
| GLN 38 | NTc.Cm11 | GLU 177 | - | HBDonor |
| GLN 38 | NTc.Cm11 | GLU 177 | - | VdWContact |
| VAL 45 | NTc.Cm4 | PRO 24 | - | Hydrophobic |
| LEU 48 | NTc.Cm1 | PHE 21 | - | Hydrophobic |
| GLU 53 | cxb1.2 | SER 23 | - | VdWContact |
| GLU 53 | cxb1.2 | PRO 24 | - | Hydrophobic |
| GLU 53 | cxb1.2 | PRO 24 | - | VdWContact |
| ILE 54 | cxb1.5 | PHE 21 | - | Hydrophobic |
| ILE 54 | cxb1.5 | PHE 21 | - | VdWContact |
| ILE 54 | cxb1.5 | SER 22 | - | VdWContact |
| CYS 55 | cxb1.6 | SER 22 | - | HBDonor |
| CYS 55 | cxb1.6 | SER 22 | - | VdWContact |
| VAL 66 | B1.5 | LEU 5 | - | Hydrophobic |
| VAL 66 | B1.5 | LEU 5 | - | VdWContact |
| ILE 70 | b1b2.6 | TYR 3 | - | Hydrophobic |
| ILE 70 | b1b2.6 | TYR 3 | - | VdWContact |
