Predicted complex interactions
CXCL6_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL6_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm48 | GLN 91 | 2.60x60 | VdWContact |
| GLY 1 | NTc.Cm48 | GLU 286 | 7.39x38 | Cationic |
| GLY 1 | NTc.Cm48 | GLU 286 | 7.39x38 | HBDonor |
| GLY 1 | NTc.Cm48 | GLU 286 | 7.39x38 | VdWContact |
| GLY 1 | NTc.Cm48 | PHE 290 | 7.43x42 | VdWContact |
| PRO 2 | NTc.Cm47 | GLN 91 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 113 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 113 | 3.32x32 | VdWContact |
| PRO 2 | NTc.Cm47 | TYR 114 | 3.33x33 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 172 | 4.64x65 | HBAcceptor |
| PRO 2 | NTc.Cm47 | TYR 172 | 4.64x65 | Hydrophobic |
| PRO 2 | NTc.Cm47 | TYR 172 | 4.64x65 | VdWContact |
| VAL 3 | NTc.Cm46 | TYR 113 | 3.32x32 | Hydrophobic |
| VAL 3 | NTc.Cm46 | TYR 114 | 3.33x33 | Hydrophobic |
| VAL 3 | NTc.Cm46 | MET 202 | 5.42x43 | Hydrophobic |
| VAL 3 | NTc.Cm46 | MET 202 | 5.42x43 | VdWContact |
| VAL 3 | NTc.Cm46 | PHE 254 | 6.51x51 | Hydrophobic |
| VAL 3 | NTc.Cm46 | LEU 258 | 6.55x55 | Hydrophobic |
| VAL 3 | NTc.Cm46 | LEU 258 | 6.55x55 | VdWContact |
| VAL 3 | NTc.Cm46 | THR 282 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm46 | GLU 286 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm45 | HIS 283 | 7.36x35 | VdWContact |
| SER 4 | NTc.Cm45 | GLU 286 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm44 | TYR 94 | 2.63x63 | Hydrophobic |
| ALA 5 | NTc.Cm44 | TYR 94 | 2.63x63 | VdWContact |
| VAL 6 | NTc.Cm43 | TYR 94 | 2.63x63 | Hydrophobic |
| VAL 6 | NTc.Cm43 | TYR 94 | 2.63x63 | VdWContact |
| VAL 6 | NTc.Cm43 | GLN 182 | - | Hydrophobic |
| LEU 7 | NTc.Cm42 | TYR 184 | 45.51x51 | Hydrophobic |
| LEU 7 | NTc.Cm42 | THR 282 | 7.35x34 | Hydrophobic |
| THR 8 | NTc.Cm41 | GLN 182 | - | HBAcceptor |
| THR 8 | NTc.Cm41 | GLN 182 | - | VdWContact |
| GLU 9 | NTc.Cm40 | ALA 27 | - | Hydrophobic |
| GLU 9 | NTc.Cm40 | LYS 195 | 5.35x36 | Anionic |
| GLU 9 | NTc.Cm40 | SER 275 | 7.28x27 | HBAcceptor |
| GLU 9 | NTc.Cm40 | SER 275 | 7.28x27 | VdWContact |
| LEU 10 | NTc.Cm39 | TYR 184 | 45.51x51 | Hydrophobic |
| LEU 10 | NTc.Cm39 | TYR 184 | 45.51x51 | VdWContact |
| LEU 10 | NTc.Cm39 | PHE 186 | - | Hydrophobic |
| LEU 10 | NTc.Cm39 | THR 191 | 5.31x32 | Hydrophobic |
| LEU 10 | NTc.Cm39 | THR 191 | 5.31x32 | VdWContact |
| LEU 10 | NTc.Cm39 | LEU 192 | 5.32x33 | VdWContact |
| LEU 10 | NTc.Cm39 | LYS 195 | 5.35x36 | Hydrophobic |
| ARG 11 | NTc.Cm38 | THR 261 | 6.58x58 | HBDonor |
| ARG 11 | NTc.Cm38 | THR 261 | 6.58x58 | VdWContact |
| ARG 11 | NTc.Cm38 | HIS 264 | 6.61x61 | CationPi |
| ARG 11 | NTc.Cm38 | HIS 264 | 6.61x61 | VdWContact |
| ARG 11 | NTc.Cm38 | SER 275 | 7.28x27 | VdWContact |
| THR 13 | NTc.Cm36 | CYS 25 | - | HBAcceptor |
| THR 13 | NTc.Cm36 | CYS 25 | - | VdWContact |
| LEU 15 | NTc.Cm34 | CYS 25 | - | Hydrophobic |
| LEU 15 | NTc.Cm34 | CYS 272 | 7.25x24 | Hydrophobic |
| VAL 17 | NTc.Cm32 | SER 22 | - | VdWContact |
| THR 18 | NTc.Cm31 | PHE 21 | - | Hydrophobic |
| THR 18 | NTc.Cm31 | PHE 21 | - | VdWContact |
| THR 18 | NTc.Cm31 | SER 22 | - | HBAcceptor |
| THR 18 | NTc.Cm31 | SER 22 | - | VdWContact |
| LEU 19 | NTc.Cm30 | TYR 17 | - | Hydrophobic |
| LEU 19 | NTc.Cm30 | TYR 17 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 15 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 15 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 16 | - | HBDonor |
| ARG 20 | NTc.Cm29 | TYR 16 | - | VdWContact |
| ARG 20 | NTc.Cm29 | TYR 17 | - | CationPi |
| ARG 20 | NTc.Cm29 | TYR 17 | - | Hydrophobic |
| ARG 20 | NTc.Cm29 | TYR 17 | - | VdWContact |
| VAL 21 | NTc.Cm28 | PHE 21 | - | Hydrophobic |
| ASN 22 | NTc.Cm27 | ASP 14 | - | HBDonor |
| ASN 22 | NTc.Cm27 | ASP 14 | - | VdWContact |
| PRO 23 | NTc.Cm26 | LEU 7 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | VAL 12 | - | Hydrophobic |
| PRO 23 | NTc.Cm26 | VAL 12 | - | VdWContact |
| ILE 26 | NTc.Cm23 | LEU 7 | - | Hydrophobic |
| LYS 28 | NTc.Cm21 | ASP 2 | - | Cationic |
| LYS 28 | NTc.Cm21 | ASP 2 | - | HBDonor |
| LYS 28 | NTc.Cm21 | ASP 2 | - | VdWContact |
| LEU 29 | NTc.Cm20 | LEU 5 | - | Hydrophobic |
| LEU 29 | NTc.Cm20 | LEU 5 | - | VdWContact |
| GLN 30 | NTc.Cm19 | ASP 2 | - | HBDonor |
| GLN 30 | NTc.Cm19 | ASP 2 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLU 177 | - | VdWContact |
| PRO 36 | NTc.Cm13 | PHE 186 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | PHE 186 | - | VdWContact |
| PRO 36 | NTc.Cm13 | GLN 189 | - | Hydrophobic |
| PRO 36 | NTc.Cm13 | THR 191 | 5.31x32 | HBAcceptor |
| PRO 36 | NTc.Cm13 | THR 191 | 5.31x32 | VdWContact |
| GLN 37 | NTc.Cm12 | GLU 177 | - | HBDonor |
| GLN 37 | NTc.Cm12 | GLU 177 | - | VdWContact |
| VAL 44 | NTc.Cm5 | PRO 24 | - | Hydrophobic |
| LEU 47 | NTc.Cm2 | PHE 21 | - | Hydrophobic |
| GLN 52 | cxb1.1 | SER 23 | - | VdWContact |
| GLN 52 | cxb1.1 | PRO 24 | - | Hydrophobic |
| VAL 53 | cxb1.2 | PHE 21 | - | Hydrophobic |
| VAL 53 | cxb1.2 | PHE 21 | - | VdWContact |
| VAL 53 | cxb1.2 | SER 22 | - | VdWContact |
| CYS 54 | cxb1.5 | SER 22 | - | HBDonor |
| CYS 54 | cxb1.5 | SER 22 | - | VdWContact |
| VAL 65 | B1.4 | LEU 5 | - | Hydrophobic |
| VAL 65 | B1.4 | LEU 5 | - | VdWContact |
| ILE 69 | b1b2.4 | TYR 3 | - | Hydrophobic |
| ILE 69 | b1b2.4 | TYR 3 | - | VdWContact |
| ILE 69 | b1b2.4 | LEU 5 | - | Hydrophobic |
| SER 72 | b1b2.8 | TYR 3 | - | VdWContact |
