Predicted complex interactions
CXCL7_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL7_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 73
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| SER 21 | NTc.Cm42 | LYS 35 | 1.32x32 | HBAcceptor |
| SER 21 | NTc.Cm42 | LYS 35 | 1.32x32 | VdWContact |
| ASP 22 | NTc.Cm41 | LYS 35 | 1.32x32 | HBAcceptor |
| ASP 22 | NTc.Cm41 | LYS 35 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm40 | GLU 28 | - | HBDonor |
| LEU 23 | NTc.Cm40 | GLU 28 | - | VdWContact |
| LEU 23 | NTc.Cm40 | ILE 30 | - | Hydrophobic |
| LEU 23 | NTc.Cm40 | LYS 35 | 1.32x32 | Hydrophobic |
| LEU 23 | NTc.Cm40 | LYS 35 | 1.32x32 | VdWContact |
| LEU 23 | NTc.Cm40 | LEU 95 | 2.64x64 | Hydrophobic |
| LEU 23 | NTc.Cm40 | LEU 95 | 2.64x64 | VdWContact |
| TYR 24 | NTc.Cm39 | GLN 91 | 2.60x60 | Hydrophobic |
| TYR 24 | NTc.Cm39 | GLN 91 | 2.60x60 | VdWContact |
| TYR 24 | NTc.Cm39 | TYR 94 | 2.63x63 | Hydrophobic |
| TYR 24 | NTc.Cm39 | TYR 94 | 2.63x63 | VdWContact |
| TYR 24 | NTc.Cm39 | LEU 95 | 2.64x64 | Hydrophobic |
| TYR 24 | NTc.Cm39 | HIS 283 | 7.36x35 | Hydrophobic |
| ALA 25 | NTc.Cm38 | GLU 28 | - | Hydrophobic |
| ALA 25 | NTc.Cm38 | GLU 28 | - | VdWContact |
| ALA 25 | NTc.Cm38 | THR 279 | 7.32x31 | Hydrophobic |
| ALA 25 | NTc.Cm38 | HIS 283 | 7.36x35 | Hydrophobic |
| GLU 26 | NTc.Cm37 | LYS 195 | 5.35x36 | Anionic |
| GLU 26 | NTc.Cm37 | LYS 195 | 5.35x36 | HBAcceptor |
| GLU 26 | NTc.Cm37 | LYS 195 | 5.35x36 | VdWContact |
| LEU 27 | NTc.Cm36 | ALA 27 | - | Hydrophobic |
| LEU 27 | NTc.Cm36 | GLU 28 | - | Hydrophobic |
| ARG 28 | NTc.Cm35 | THR 261 | 6.58x58 | HBDonor |
| ARG 28 | NTc.Cm35 | THR 261 | 6.58x58 | VdWContact |
| ARG 28 | NTc.Cm35 | HIS 264 | 6.61x61 | CationPi |
| ARG 28 | NTc.Cm35 | SER 265 | 6.62x62 | HBDonor |
| ARG 28 | NTc.Cm35 | SER 275 | 7.28x27 | HBDonor |
| ARG 28 | NTc.Cm35 | SER 275 | 7.28x27 | VdWContact |
| MET 30 | NTc.Cm33 | PRO 24 | - | Hydrophobic |
| MET 30 | NTc.Cm33 | PRO 24 | - | VdWContact |
| MET 30 | NTc.Cm33 | CYS 25 | - | HBAcceptor |
| MET 30 | NTc.Cm33 | CYS 25 | - | VdWContact |
| ILE 32 | NTc.Cm31 | CYS 25 | - | Hydrophobic |
| ILE 32 | NTc.Cm31 | HIS 264 | 6.61x61 | Hydrophobic |
| ILE 32 | NTc.Cm31 | ASP 270 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | PHE 21 | - | Hydrophobic |
| LYS 33 | NTc.Cm30 | PHE 21 | - | VdWContact |
| THR 35 | NTc.Cm28 | PRO 18 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 15 | - | Hydrophobic |
| HIS 39 | NTc.Cm24 | TYR 15 | - | VdWContact |
| LYS 41 | NTc.Cm22 | TYR 15 | - | Hydrophobic |
| LYS 41 | NTc.Cm22 | TYR 15 | - | VdWContact |
| ASN 42 | NTc.Cm21 | TYR 15 | - | VdWContact |
| GLY 52 | NTc.Cm11 | GLU 177 | - | VdWContact |
| THR 53 | NTc.Cm10 | GLU 177 | - | HBDonor |
| THR 53 | NTc.Cm10 | GLU 177 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | GLU 177 | - | VdWContact |
| THR 53 | NTc.Cm10 | TYR 184 | 45.51x51 | VdWContact |
| THR 53 | NTc.Cm10 | PHE 186 | - | Hydrophobic |
| THR 53 | NTc.Cm10 | PHE 186 | - | VdWContact |
| THR 53 | NTc.Cm10 | THR 191 | 5.31x32 | HBAcceptor |
| THR 53 | NTc.Cm10 | THR 191 | 5.31x32 | VdWContact |
| HIS 54 | NTc.Cm9 | GLN 182 | - | HBDonor |
| HIS 54 | NTc.Cm9 | GLN 182 | - | VdWContact |
| HIS 54 | NTc.Cm9 | TYR 184 | 45.51x51 | Hydrophobic |
| ILE 61 | NTc.Cm2 | PRO 24 | - | Hydrophobic |
| LEU 64 | CX.4 | PRO 18 | - | Hydrophobic |
| ARG 68 | cxb1.5 | TYR 17 | - | VdWContact |
| LYS 69 | cxb1.6 | PRO 24 | - | Hydrophobic |
| LYS 69 | cxb1.6 | PRO 24 | - | VdWContact |
| LYS 69 | cxb1.6 | ASP 26 | - | Cationic |
| LYS 69 | cxb1.6 | ASP 26 | - | HBDonor |
| LYS 69 | cxb1.6 | ASP 26 | - | VdWContact |
| ILE 70 | cxb1.8 | PRO 18 | - | Hydrophobic |
| ILE 70 | cxb1.8 | PRO 18 | - | VdWContact |
| ILE 70 | cxb1.8 | SER 22 | - | VdWContact |
| CYS 71 | cxb1.10 | SER 22 | - | HBDonor |
| CYS 71 | cxb1.10 | SER 22 | - | VdWContact |
| CYS 71 | cxb1.10 | PRO 24 | - | VdWContact |
