Predicted complex interactions
CXCL8_HUMAN + CCR8
SUMMARY
- Chemokine
- CXCL8_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 118
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLU 1 | NTc.Cm33 | GLU 28 | - | Cationic |
| GLU 1 | NTc.Cm33 | GLU 28 | - | HBDonor |
| GLU 1 | NTc.Cm33 | GLU 28 | - | VdWContact |
| GLU 1 | NTc.Cm33 | LYS 35 | 1.32x32 | Anionic |
| GLU 1 | NTc.Cm33 | LYS 35 | 1.32x32 | HBAcceptor |
| GLU 1 | NTc.Cm33 | LYS 35 | 1.32x32 | Hydrophobic |
| GLU 1 | NTc.Cm33 | LYS 35 | 1.32x32 | VdWContact |
| GLU 1 | NTc.Cm33 | LEU 95 | 2.64x64 | VdWContact |
| GLY 2 | NTc.Cm32 | TYR 94 | 2.63x63 | HBDonor |
| GLY 2 | NTc.Cm32 | TYR 94 | 2.63x63 | VdWContact |
| ALA 3 | NTc.Cm31 | TYR 42 | 1.39x39 | Hydrophobic |
| ALA 3 | NTc.Cm31 | TYR 42 | 1.39x39 | VdWContact |
| ALA 3 | NTc.Cm31 | GLN 91 | 2.60x60 | VdWContact |
| ALA 3 | NTc.Cm31 | LEU 95 | 2.64x64 | Hydrophobic |
| ALA 3 | NTc.Cm31 | LEU 95 | 2.64x64 | VdWContact |
| ALA 3 | NTc.Cm31 | GLU 286 | 7.39x38 | VdWContact |
| VAL 4 | NTc.Cm30 | GLN 91 | 2.60x60 | Hydrophobic |
| VAL 4 | NTc.Cm30 | GLN 91 | 2.60x60 | VdWContact |
| VAL 4 | NTc.Cm30 | VAL 109 | 3.28x28 | Hydrophobic |
| VAL 4 | NTc.Cm30 | VAL 109 | 3.28x28 | VdWContact |
| VAL 4 | NTc.Cm30 | TYR 113 | 3.32x32 | Hydrophobic |
| VAL 4 | NTc.Cm30 | TYR 113 | 3.32x32 | VdWContact |
| VAL 4 | NTc.Cm30 | PHE 290 | 7.43x42 | VdWContact |
| LEU 5 | NTc.Cm29 | TYR 113 | 3.32x32 | Hydrophobic |
| LEU 5 | NTc.Cm29 | TYR 113 | 3.32x32 | VdWContact |
| LEU 5 | NTc.Cm29 | PHE 254 | 6.51x51 | Hydrophobic |
| LEU 5 | NTc.Cm29 | PHE 254 | 6.51x51 | VdWContact |
| LEU 5 | NTc.Cm29 | THR 282 | 7.35x34 | Hydrophobic |
| LEU 5 | NTc.Cm29 | THR 282 | 7.35x34 | VdWContact |
| LEU 5 | NTc.Cm29 | GLU 286 | 7.39x38 | Hydrophobic |
| LEU 5 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| LEU 5 | NTc.Cm29 | PHE 290 | 7.43x42 | Hydrophobic |
| LEU 5 | NTc.Cm29 | PHE 290 | 7.43x42 | VdWContact |
| PRO 6 | NTc.Cm28 | TYR 113 | 3.32x32 | VdWContact |
| PRO 6 | NTc.Cm28 | TYR 114 | 3.33x33 | Hydrophobic |
| PRO 6 | NTc.Cm28 | TYR 114 | 3.33x33 | VdWContact |
| PRO 6 | NTc.Cm28 | TYR 172 | 4.64x65 | VdWContact |
| PRO 6 | NTc.Cm28 | TYR 184 | 45.51x51 | Hydrophobic |
| PRO 6 | NTc.Cm28 | MET 202 | 5.42x43 | Hydrophobic |
| PRO 6 | NTc.Cm28 | MET 202 | 5.42x43 | VdWContact |
| ARG 7 | NTc.Cm27 | TYR 94 | 2.63x63 | Hydrophobic |
| ARG 7 | NTc.Cm27 | TYR 94 | 2.63x63 | VdWContact |
| ARG 7 | NTc.Cm27 | GLN 182 | - | HBDonor |
| ARG 7 | NTc.Cm27 | GLN 182 | - | VdWContact |
| ARG 7 | NTc.Cm27 | CYS 183 | 45.50x50 | VdWContact |
| ARG 7 | NTc.Cm27 | TYR 184 | 45.51x51 | Hydrophobic |
| ARG 7 | NTc.Cm27 | TYR 184 | 45.51x51 | VdWContact |
| SER 8 | NTc.Cm26 | LYS 195 | 5.35x36 | VdWContact |
| ALA 9 | NTc.Cm25 | THR 279 | 7.32x31 | VdWContact |
| ALA 9 | NTc.Cm25 | THR 282 | 7.35x34 | Hydrophobic |
| ALA 9 | NTc.Cm25 | THR 282 | 7.35x34 | VdWContact |
| ALA 9 | NTc.Cm25 | HIS 283 | 7.36x35 | Hydrophobic |
| LYS 10 | NTc.Cm24 | GLU 28 | - | Cationic |
| LYS 10 | NTc.Cm24 | GLU 28 | - | VdWContact |
| GLU 11 | NTc.Cm23 | ALA 27 | - | Hydrophobic |
| GLU 11 | NTc.Cm23 | ALA 27 | - | VdWContact |
| GLU 11 | NTc.Cm23 | THR 279 | 7.32x31 | HBAcceptor |
| GLU 11 | NTc.Cm23 | THR 279 | 7.32x31 | Hydrophobic |
| GLU 11 | NTc.Cm23 | THR 279 | 7.32x31 | VdWContact |
| LEU 12 | NTc.Cm22 | TYR 184 | 45.51x51 | Hydrophobic |
| LEU 12 | NTc.Cm22 | TYR 184 | 45.51x51 | VdWContact |
| LEU 12 | NTc.Cm22 | THR 191 | 5.31x32 | Hydrophobic |
| LEU 12 | NTc.Cm22 | THR 191 | 5.31x32 | VdWContact |
| LEU 12 | NTc.Cm22 | LYS 195 | 5.35x36 | Hydrophobic |
| ARG 13 | NTc.Cm21 | HIS 264 | 6.61x61 | CationPi |
| ARG 13 | NTc.Cm21 | HIS 264 | 6.61x61 | VdWContact |
| ARG 13 | NTc.Cm21 | SER 275 | 7.28x27 | HBDonor |
| ARG 13 | NTc.Cm21 | SER 275 | 7.28x27 | VdWContact |
| GLN 15 | NTc.Cm19 | PRO 24 | - | Hydrophobic |
| GLN 15 | NTc.Cm19 | PRO 24 | - | VdWContact |
| GLN 15 | NTc.Cm19 | CYS 25 | - | HBAcceptor |
| GLN 15 | NTc.Cm19 | CYS 25 | - | VdWContact |
| ILE 17 | NTc.Cm17 | CYS 25 | - | Hydrophobic |
| ILE 17 | NTc.Cm17 | CYS 272 | 7.25x24 | Hydrophobic |
| LYS 18 | NTc.Cm16 | SER 22 | - | VdWContact |
| TYR 20 | NTc.Cm14 | PRO 18 | - | Hydrophobic |
| TYR 20 | NTc.Cm14 | PRO 18 | - | VdWContact |
| TYR 20 | NTc.Cm14 | ASP 19 | - | HBAcceptor |
| TYR 20 | NTc.Cm14 | ASP 19 | - | HBDonor |
| TYR 20 | NTc.Cm14 | ASP 19 | - | VdWContact |
| TYR 20 | NTc.Cm14 | SER 22 | - | VdWContact |
| LYS 22 | NTc.Cm12 | ASP 19 | - | Cationic |
| PHE 24 | NTc.Cm10 | PRO 18 | - | Hydrophobic |
| PHE 24 | NTc.Cm10 | PRO 18 | - | VdWContact |
| HIS 25 | NTc.Cm9 | TYR 15 | - | Hydrophobic |
| HIS 25 | NTc.Cm9 | TYR 15 | - | VdWContact |
| PHE 28 | NTc.Cm6 | TYR 15 | - | Hydrophobic |
| PHE 28 | NTc.Cm6 | TYR 15 | - | VdWContact |
| PHE 28 | NTc.Cm6 | TYR 17 | - | Hydrophobic |
| ARG 33 | NTc.Cm1 | ASP 178 | - | Cationic |
| ARG 33 | NTc.Cm1 | ASP 178 | - | HBDonor |
| ARG 33 | NTc.Cm1 | ASP 178 | - | VdWContact |
| PRO 39 | cxb1.5 | GLU 177 | - | VdWContact |
| PRO 39 | cxb1.5 | PHE 186 | - | Hydrophobic |
| PRO 39 | cxb1.5 | PHE 186 | - | VdWContact |
| PRO 39 | cxb1.5 | THR 191 | 5.31x32 | Hydrophobic |
| PRO 39 | cxb1.5 | THR 191 | 5.31x32 | VdWContact |
| HIS 40 | cxb1.6 | GLU 177 | - | HBDonor |
| HIS 40 | cxb1.6 | GLU 177 | - | VdWContact |
| ILE 47 | cxb1.16 | PRO 24 | - | Hydrophobic |
| LEU 50 | B1.3 | TYR 17 | - | Hydrophobic |
| LEU 50 | B1.3 | TYR 17 | - | VdWContact |
| LEU 50 | B1.3 | PRO 18 | - | Hydrophobic |
| SER 51 | B1.4 | TYR 17 | - | VdWContact |
| ASP 52 | B1.5 | TYR 17 | - | HBDonor |
| ASP 52 | B1.5 | TYR 17 | - | Hydrophobic |
| ASP 52 | B1.5 | TYR 17 | - | VdWContact |
| ARG 54 | B1.7 | TYR 17 | - | VdWContact |
| ARG 54 | B1.7 | PRO 18 | - | HBDonor |
| ARG 54 | B1.7 | PRO 18 | - | VdWContact |
| ARG 54 | B1.7 | ILE 20 | - | VdWContact |
| GLU 55 | b1b2.4 | SER 23 | - | VdWContact |
| GLU 55 | b1b2.4 | PRO 24 | - | Hydrophobic |
| LEU 56 | b1b2.6 | PRO 18 | - | Hydrophobic |
| LEU 56 | b1b2.6 | PRO 18 | - | VdWContact |
| LEU 56 | b1b2.6 | SER 22 | - | VdWContact |
| CYS 57 | b1b2.7 | SER 22 | - | HBDonor |
| CYS 57 | b1b2.7 | SER 22 | - | VdWContact |
