Predicted complex interactions
XCL2_HUMAN + CCR8
SUMMARY
- Chemokine
- XCL2_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR8 View partner entry
- Partner description
- UniProt: P51685; Gene: ccr8_human; Family: Chemokine
- Interactions detected
- 75
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| VAL 1 | NTc.Cm30 | TYR 113 | 3.32x32 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 113 | 3.32x32 | VdWContact |
| VAL 1 | NTc.Cm30 | TYR 114 | 3.33x33 | Hydrophobic |
| VAL 1 | NTc.Cm30 | TYR 114 | 3.33x33 | VdWContact |
| VAL 1 | NTc.Cm30 | MET 202 | 5.42x43 | Hydrophobic |
| GLY 2 | NTc.Cm29 | THR 282 | 7.35x34 | VdWContact |
| GLY 2 | NTc.Cm29 | GLU 286 | 7.39x38 | HBDonor |
| GLY 2 | NTc.Cm29 | GLU 286 | 7.39x38 | VdWContact |
| SER 3 | NTc.Cm28 | TYR 42 | 1.39x39 | HBAcceptor |
| SER 3 | NTc.Cm28 | TYR 42 | 1.39x39 | VdWContact |
| SER 3 | NTc.Cm28 | HIS 283 | 7.36x35 | VdWContact |
| SER 3 | NTc.Cm28 | GLU 286 | 7.39x38 | HBDonor |
| SER 3 | NTc.Cm28 | GLU 286 | 7.39x38 | VdWContact |
| GLU 4 | NTc.Cm27 | TYR 94 | 2.63x63 | Hydrophobic |
| GLU 4 | NTc.Cm27 | TYR 172 | 4.64x65 | HBAcceptor |
| GLU 4 | NTc.Cm27 | TYR 172 | 4.64x65 | VdWContact |
| GLU 4 | NTc.Cm27 | CYS 183 | 45.50x50 | VdWContact |
| GLU 4 | NTc.Cm27 | TYR 184 | 45.51x51 | Hydrophobic |
| GLU 4 | NTc.Cm27 | TYR 184 | 45.51x51 | VdWContact |
| VAL 5 | NTc.Cm26 | ALA 27 | - | Hydrophobic |
| VAL 5 | NTc.Cm26 | GLU 28 | - | Hydrophobic |
| VAL 5 | NTc.Cm26 | THR 279 | 7.32x31 | Hydrophobic |
| VAL 5 | NTc.Cm26 | THR 279 | 7.32x31 | VdWContact |
| VAL 5 | NTc.Cm26 | HIS 283 | 7.36x35 | Hydrophobic |
| SER 6 | NTc.Cm25 | GLN 182 | - | VdWContact |
| HIS 7 | NTc.Cm24 | GLU 28 | - | Hydrophobic |
| HIS 7 | NTc.Cm24 | GLU 28 | - | VdWContact |
| HIS 7 | NTc.Cm24 | GLN 182 | - | VdWContact |
| ARG 8 | NTc.Cm23 | GLU 177 | - | Cationic |
| ARG 8 | NTc.Cm23 | GLU 177 | - | HBDonor |
| ARG 8 | NTc.Cm23 | GLU 177 | - | Hydrophobic |
| ARG 8 | NTc.Cm23 | GLU 177 | - | VdWContact |
| ARG 9 | NTc.Cm22 | PRO 24 | - | Hydrophobic |
| ARG 9 | NTc.Cm22 | PRO 24 | - | VdWContact |
| ARG 9 | NTc.Cm22 | CYS 25 | - | VdWContact |
| ARG 9 | NTc.Cm22 | ASP 26 | - | Cationic |
| ARG 9 | NTc.Cm22 | ASP 26 | - | HBDonor |
| ARG 9 | NTc.Cm22 | ASP 26 | - | VdWContact |
| ARG 9 | NTc.Cm22 | ASP 178 | - | Cationic |
| THR 10 | NTc.Cm21 | CYS 25 | - | HBAcceptor |
| THR 10 | NTc.Cm21 | CYS 25 | - | VdWContact |
| VAL 12 | NTc.Cm19 | CYS 25 | - | Hydrophobic |
| VAL 12 | NTc.Cm19 | HIS 264 | 6.61x61 | Hydrophobic |
| VAL 12 | NTc.Cm19 | CYS 272 | 7.25x24 | Hydrophobic |
| SER 13 | NTc.Cm18 | SER 22 | - | VdWContact |
| THR 15 | NTc.Cm16 | PHE 21 | - | Hydrophobic |
| THR 15 | NTc.Cm16 | PHE 21 | - | VdWContact |
| THR 15 | NTc.Cm16 | SER 22 | - | HBAcceptor |
| THR 15 | NTc.Cm16 | SER 22 | - | HBDonor |
| THR 15 | NTc.Cm16 | SER 22 | - | VdWContact |
| GLN 17 | NTc.Cm14 | PHE 21 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TYR 17 | - | Hydrophobic |
| LEU 19 | NTc.Cm12 | TYR 17 | - | VdWContact |
| LEU 19 | NTc.Cm12 | PHE 21 | - | Hydrophobic |
| ARG 23 | NTc.Cm8 | TYR 15 | - | CationPi |
| ARG 23 | NTc.Cm8 | TYR 15 | - | VdWContact |
| ARG 23 | NTc.Cm8 | TYR 17 | - | VdWContact |
| SER 33 | cxb1.1 | LEU 192 | 5.32x33 | VdWContact |
| LEU 34 | cxb1.2 | HIS 267 | 6.64x64 | Hydrophobic |
| ILE 38 | cxb1.8 | PRO 24 | - | Hydrophobic |
| THR 41 | cxb1.14 | TYR 17 | - | Hydrophobic |
| ARG 43 | cxb1.16 | ASP 14 | - | Cationic |
| ARG 43 | cxb1.16 | ASP 14 | - | HBDonor |
| ARG 43 | cxb1.16 | ASP 14 | - | VdWContact |
| LEU 45 | B1.2 | TYR 17 | - | Hydrophobic |
| LYS 46 | B1.3 | SER 23 | - | VdWContact |
| LYS 46 | B1.3 | PRO 24 | - | Hydrophobic |
| LYS 46 | B1.3 | PRO 24 | - | VdWContact |
| LYS 46 | B1.3 | ASP 178 | - | Cationic |
| VAL 47 | B1.4 | PHE 21 | - | Hydrophobic |
| VAL 47 | B1.4 | PHE 21 | - | VdWContact |
| VAL 47 | B1.4 | SER 22 | - | VdWContact |
| CYS 48 | B1.5 | SER 22 | - | HBDonor |
| CYS 48 | B1.5 | SER 22 | - | VdWContact |
| CYS 48 | B1.5 | PRO 24 | - | VdWContact |
