Predicted complex interactions
CCL22_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL22_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 93
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLY 1 | NTc.Cm35 | SER 121 | 3.29x29 | VdWContact |
| GLY 1 | NTc.Cm35 | TYR 124 | 3.32x32 | VdWContact |
| GLY 1 | NTc.Cm35 | ASP 179 | 4.60x61 | Cationic |
| PRO 2 | NTc.Cm34 | TRP 102 | 2.60x60 | Hydrophobic |
| PRO 2 | NTc.Cm34 | TRP 102 | 2.60x60 | VdWContact |
| PRO 2 | NTc.Cm34 | TYR 124 | 3.32x32 | Hydrophobic |
| PRO 2 | NTc.Cm34 | GLU 298 | 7.39x38 | VdWContact |
| PRO 2 | NTc.Cm34 | PHE 302 | 7.43x42 | Hydrophobic |
| PRO 2 | NTc.Cm34 | PHE 302 | 7.43x42 | VdWContact |
| TYR 3 | NTc.Cm33 | ARG 211 | 5.39x40 | Hydrophobic |
| TYR 3 | NTc.Cm33 | GLN 214 | 5.42x43 | VdWContact |
| TYR 3 | NTc.Cm33 | TYR 266 | 6.51x51 | VdWContact |
| TYR 3 | NTc.Cm33 | LEU 270 | 6.55x55 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 294 | 7.35x34 | Hydrophobic |
| TYR 3 | NTc.Cm33 | LEU 294 | 7.35x34 | VdWContact |
| TYR 3 | NTc.Cm33 | GLU 298 | 7.39x38 | HBDonor |
| TYR 3 | NTc.Cm33 | GLU 298 | 7.39x38 | VdWContact |
| GLY 4 | NTc.Cm32 | GLN 295 | 7.36x35 | VdWContact |
| GLY 4 | NTc.Cm32 | GLU 298 | 7.39x38 | HBDonor |
| GLY 4 | NTc.Cm32 | GLU 298 | 7.39x38 | VdWContact |
| ALA 5 | NTc.Cm31 | VAL 106 | 2.64x64 | Hydrophobic |
| MET 7 | NTc.Cm29 | VAL 42 | 1.28x28 | Hydrophobic |
| MET 7 | NTc.Cm29 | VAL 42 | 1.28x28 | VdWContact |
| MET 7 | NTc.Cm29 | GLY 45 | 1.31x31 | VdWContact |
| MET 7 | NTc.Cm29 | LEU 49 | 1.35x35 | Hydrophobic |
| MET 7 | NTc.Cm29 | VAL 106 | 2.64x64 | Hydrophobic |
| GLU 8 | NTc.Cm28 | HIS 196 | 45.51x51 | Hydrophobic |
| GLU 8 | NTc.Cm28 | HIS 196 | 45.51x51 | VdWContact |
| ASP 9 | NTc.Cm27 | LYS 38 | 1.24x24 | HBAcceptor |
| ASP 9 | NTc.Cm27 | LYS 38 | 1.24x24 | VdWContact |
| ASP 9 | NTc.Cm27 | LYS 207 | 5.35x36 | Anionic |
| ASP 9 | NTc.Cm27 | LYS 207 | 5.35x36 | HBAcceptor |
| ASP 9 | NTc.Cm27 | LYS 207 | 5.35x36 | VdWContact |
| SER 10 | NTc.Cm26 | ARG 37 | - | VdWContact |
| SER 10 | NTc.Cm26 | LYS 38 | 1.24x24 | HBAcceptor |
| SER 10 | NTc.Cm26 | LYS 38 | 1.24x24 | VdWContact |
| VAL 11 | NTc.Cm25 | LEU 35 | - | Hydrophobic |
| VAL 11 | NTc.Cm25 | LEU 35 | - | VdWContact |
| VAL 11 | NTc.Cm25 | CYS 36 | - | VdWContact |
| VAL 11 | NTc.Cm25 | ARG 37 | - | Hydrophobic |
| CYS 12 | NTc.Cm24 | CYS 36 | - | HBAcceptor |
| CYS 12 | NTc.Cm24 | CYS 36 | - | HBDonor |
| CYS 12 | NTc.Cm24 | CYS 36 | - | VdWContact |
| ARG 14 | NTc.Cm22 | MET 34 | - | HBDonor |
| ARG 14 | NTc.Cm22 | MET 34 | - | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 36 | - | Cationic |
| ARG 14 | NTc.Cm22 | CYS 36 | - | Hydrophobic |
| ARG 14 | NTc.Cm22 | CYS 36 | - | VdWContact |
| ARG 14 | NTc.Cm22 | GLY 282 | - | HBDonor |
| ARG 14 | NTc.Cm22 | GLY 282 | - | VdWContact |
| ARG 14 | NTc.Cm22 | ASN 283 | 7.24x23 | VdWContact |
| ARG 14 | NTc.Cm22 | CYS 284 | 7.25x24 | Cationic |
| ARG 14 | NTc.Cm22 | CYS 284 | 7.25x24 | VdWContact |
| ASP 15 | NTc.Cm21 | MET 34 | - | Hydrophobic |
| ASP 15 | NTc.Cm21 | MET 34 | - | VdWContact |
| TYR 16 | NTc.Cm20 | MET 34 | - | VdWContact |
| VAL 17 | NTc.Cm19 | TYR 27 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | VAL 31 | - | Hydrophobic |
| VAL 17 | NTc.Cm19 | VAL 31 | - | VdWContact |
| TYR 19 | NTc.Cm17 | TYR 27 | - | Hydrophobic |
| TYR 19 | NTc.Cm17 | TYR 27 | - | VdWContact |
| ARG 20 | NTc.Cm16 | TYR 24 | - | VdWContact |
| LEU 21 | NTc.Cm15 | TYR 24 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | LEU 28 | - | Hydrophobic |
| LEU 21 | NTc.Cm15 | LEU 28 | - | VdWContact |
| PRO 22 | NTc.Cm14 | TYR 24 | - | Hydrophobic |
| ARG 24 | NTc.Cm12 | SER 17 | - | HBDonor |
| ARG 24 | NTc.Cm12 | SER 17 | - | VdWContact |
| VAL 25 | NTc.Cm11 | TYR 25 | - | Hydrophobic |
| ARG 38 | cxb1.1 | GLN 279 | 6.64x64 | HBDonor |
| ARG 38 | cxb1.1 | GLN 279 | 6.64x64 | VdWContact |
| VAL 42 | cxb1.7 | LEU 35 | - | Hydrophobic |
| THR 45 | cxb1.11 | LEU 28 | - | Hydrophobic |
| ARG 47 | cxb1.15 | TYR 25 | - | CationPi |
| ARG 47 | cxb1.15 | TYR 25 | - | Hydrophobic |
| ARG 47 | cxb1.15 | TYR 25 | - | VdWContact |
| LYS 49 | B1.1 | TYR 25 | - | HBDonor |
| LYS 49 | B1.1 | TYR 25 | - | VdWContact |
| LYS 49 | B1.1 | LEU 28 | - | Hydrophobic |
| LYS 49 | B1.1 | ASP 29 | - | Cationic |
| LYS 49 | B1.1 | ASP 29 | - | HBDonor |
| LYS 49 | B1.1 | ASP 29 | - | VdWContact |
| GLU 50 | B1.2 | LEU 35 | - | Hydrophobic |
| GLU 50 | B1.2 | LEU 35 | - | VdWContact |
| GLU 50 | B1.2 | ARG 37 | - | Anionic |
| GLU 50 | B1.2 | ARG 37 | - | HBAcceptor |
| GLU 50 | B1.2 | ARG 37 | - | VdWContact |
| ILE 51 | B1.3 | LEU 28 | - | Hydrophobic |
| ILE 51 | B1.3 | LEU 28 | - | VdWContact |
| ILE 51 | B1.3 | VAL 31 | - | Hydrophobic |
| ILE 51 | B1.3 | VAL 31 | - | VdWContact |
| CYS 52 | B1.4 | MET 34 | - | Hydrophobic |
| CYS 52 | B1.4 | LEU 35 | - | VdWContact |
