Predicted complex interactions
CXCL12_HUMAN + CCR9
SUMMARY
- Chemokine
- CXCL12_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- CCR9 View partner entry
- Partner description
- UniProt: P51686; Gene: ccr9_human; Family: Chemokine
- Interactions detected
- 103
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| LYS 1 | NTc.Cm29 | ALA 107 | 2.63x63 | HBDonor |
| LYS 1 | NTc.Cm29 | ALA 107 | 2.63x63 | VdWContact |
| LYS 1 | NTc.Cm29 | ASP 110 | 2.66x66 | Cationic |
| LYS 1 | NTc.Cm29 | ASP 110 | 2.66x66 | HBDonor |
| LYS 1 | NTc.Cm29 | ASP 110 | 2.66x66 | VdWContact |
| LYS 1 | NTc.Cm29 | GLN 111 | 23.49x49 | HBDonor |
| LYS 1 | NTc.Cm29 | GLN 111 | 23.49x49 | Hydrophobic |
| LYS 1 | NTc.Cm29 | GLN 111 | 23.49x49 | VdWContact |
| LYS 1 | NTc.Cm29 | GLY 194 | - | HBDonor |
| LYS 1 | NTc.Cm29 | GLY 194 | - | VdWContact |
| LYS 1 | NTc.Cm29 | ILE 195 | - | Hydrophobic |
| LYS 1 | NTc.Cm29 | ILE 195 | - | VdWContact |
| LYS 1 | NTc.Cm29 | ALA 196 | - | VdWContact |
| LYS 1 | NTc.Cm29 | ILE 197 | - | Hydrophobic |
| PRO 2 | NTc.Cm28 | LEU 51 | 1.35x35 | Hydrophobic |
| PRO 2 | NTc.Cm28 | ALA 108 | 2.64x64 | Hydrophobic |
| PRO 2 | NTc.Cm28 | ALA 108 | 2.64x64 | VdWContact |
| VAL 3 | NTc.Cm27 | LEU 51 | 1.35x35 | Hydrophobic |
| VAL 3 | NTc.Cm27 | LEU 51 | 1.35x35 | VdWContact |
| VAL 3 | NTc.Cm27 | TYR 55 | 1.39x39 | Hydrophobic |
| VAL 3 | NTc.Cm27 | TYR 55 | 1.39x39 | VdWContact |
| VAL 3 | NTc.Cm27 | PHE 299 | 7.35x34 | Hydrophobic |
| VAL 3 | NTc.Cm27 | PHE 299 | 7.35x34 | VdWContact |
| VAL 3 | NTc.Cm27 | GLN 300 | 7.36x35 | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLN 303 | 7.39x38 | Hydrophobic |
| VAL 3 | NTc.Cm27 | GLN 303 | 7.39x38 | VdWContact |
| SER 4 | NTc.Cm26 | ILE 197 | - | VdWContact |
| SER 4 | NTc.Cm26 | PHE 299 | 7.35x34 | VdWContact |
| LEU 5 | NTc.Cm25 | LYS 40 | - | Hydrophobic |
| LEU 5 | NTc.Cm25 | VAL 43 | 1.27x27 | Hydrophobic |
| LEU 5 | NTc.Cm25 | ASP 296 | 7.32x31 | Hydrophobic |
| LEU 5 | NTc.Cm25 | ASP 296 | 7.32x31 | VdWContact |
| LEU 5 | NTc.Cm25 | GLN 300 | 7.36x35 | Hydrophobic |
| LEU 5 | NTc.Cm25 | GLN 300 | 7.36x35 | VdWContact |
| TYR 7 | NTc.Cm23 | LYS 40 | - | Hydrophobic |
| TYR 7 | NTc.Cm23 | LYS 40 | - | VdWContact |
| TYR 7 | NTc.Cm23 | ARG 44 | 1.28x28 | Hydrophobic |
| TYR 7 | NTc.Cm23 | ARG 44 | 1.28x28 | PiCation |
| TYR 7 | NTc.Cm23 | ARG 44 | 1.28x28 | VdWContact |
| TYR 7 | NTc.Cm23 | GLU 192 | - | HBDonor |
| TYR 7 | NTc.Cm23 | GLU 192 | - | Hydrophobic |
| TYR 7 | NTc.Cm23 | GLU 192 | - | VdWContact |
| ARG 8 | NTc.Cm22 | VAL 276 | 6.57x57 | HBDonor |
| ARG 8 | NTc.Cm22 | VAL 276 | 6.57x57 | VdWContact |
| ARG 8 | NTc.Cm22 | GLN 277 | 6.58x58 | VdWContact |
| ARG 8 | NTc.Cm22 | ASP 280 | 6.61x61 | Cationic |
| ARG 8 | NTc.Cm22 | ASP 280 | 6.61x61 | VdWContact |
| ARG 8 | NTc.Cm22 | ILE 286 | - | VdWContact |
| ARG 12 | NTc.Cm18 | ASP 280 | 6.61x61 | Cationic |
| ARG 12 | NTc.Cm18 | ASP 280 | 6.61x61 | HBDonor |
| ARG 12 | NTc.Cm18 | ASP 280 | 6.61x61 | VdWContact |
| ARG 12 | NTc.Cm18 | MET 284 | 6.65x65 | Hydrophobic |
| ARG 12 | NTc.Cm18 | MET 284 | 6.65x65 | VdWContact |
| ARG 12 | NTc.Cm18 | ILE 286 | - | VdWContact |
| PHE 13 | NTc.Cm17 | MET 284 | 6.65x65 | Hydrophobic |
| PHE 13 | NTc.Cm17 | MET 284 | 6.65x65 | VdWContact |
| LYS 24 | NTc.Cm6 | TYR 28 | - | VdWContact |
| LYS 24 | NTc.Cm6 | PHE 31 | - | Hydrophobic |
| HIS 25 | NTc.Cm5 | ASP 27 | - | VdWContact |
| HIS 25 | NTc.Cm5 | TYR 28 | - | HBDonor |
| HIS 25 | NTc.Cm5 | TYR 28 | - | Hydrophobic |
| HIS 25 | NTc.Cm5 | TYR 28 | - | VdWContact |
| HIS 25 | NTc.Cm5 | PHE 31 | - | Hydrophobic |
| HIS 25 | NTc.Cm5 | PHE 31 | - | PiStacking |
| HIS 25 | NTc.Cm5 | PHE 31 | - | VdWContact |
| LYS 27 | NTc.Cm3 | PHE 33 | - | VdWContact |
| LYS 27 | NTc.Cm3 | PHE 36 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | PHE 36 | - | VdWContact |
| LYS 27 | NTc.Cm3 | TYR 37 | - | Hydrophobic |
| LYS 27 | NTc.Cm3 | TYR 37 | - | VdWContact |
| LEU 29 | NTc.Cm1 | TYR 37 | - | Hydrophobic |
| LEU 29 | NTc.Cm1 | TYR 37 | - | VdWContact |
| PRO 32 | CX.5 | GLU 191 | - | Hydrophobic |
| PRO 32 | CX.5 | GLU 191 | - | VdWContact |
| PRO 32 | CX.5 | GLU 192 | - | VdWContact |
| PRO 32 | CX.5 | SER 193 | - | VdWContact |
| ASN 33 | cxb1.1 | LYS 190 | - | HBAcceptor |
| ASN 33 | cxb1.1 | LYS 190 | - | Hydrophobic |
| ASN 33 | cxb1.1 | LYS 190 | - | VdWContact |
| ASN 33 | cxb1.1 | GLU 191 | - | VdWContact |
| ASN 33 | cxb1.1 | GLU 192 | - | HBDonor |
| ASN 33 | cxb1.1 | GLU 192 | - | Hydrophobic |
| ASN 33 | cxb1.1 | GLU 192 | - | VdWContact |
| VAL 39 | cxb1.11 | PHE 36 | - | Hydrophobic |
| VAL 39 | cxb1.11 | PHE 36 | - | VdWContact |
| ARG 41 | cxb1.15 | PHE 31 | - | CationPi |
| ARG 41 | cxb1.15 | PHE 31 | - | Hydrophobic |
| ARG 41 | cxb1.15 | PHE 31 | - | VdWContact |
| ARG 41 | cxb1.15 | ASP 35 | - | Cationic |
| ARG 41 | cxb1.15 | ASP 35 | - | HBDonor |
| ARG 41 | cxb1.15 | ASP 35 | - | VdWContact |
| ARG 41 | cxb1.15 | PHE 36 | - | Hydrophobic |
| ARG 41 | cxb1.15 | PHE 36 | - | VdWContact |
| GLN 48 | B1.6 | PHE 36 | - | Hydrophobic |
| GLN 48 | B1.6 | PHE 36 | - | VdWContact |
| LYS 68 | b2b3.12 | ILE 10 | - | Hydrophobic |
| LYS 68 | b2b3.12 | ILE 10 | - | VdWContact |
| LYS 71 | B3.3 | ILE 10 | - | Hydrophobic |
| MET 72 | B3.4 | PHE 6 | - | VdWContact |
| MET 72 | B3.4 | SER 8 | - | HBAcceptor |
| MET 72 | B3.4 | SER 8 | - | VdWContact |
| MET 72 | B3.4 | ILE 10 | - | Hydrophobic |
| MET 72 | B3.4 | ILE 10 | - | VdWContact |
