Predicted complex interactions
CCL25_HUMAN + ACKR2
SUMMARY
- Chemokine
- CCL25_HUMAN View chemokine entry
- Chemokine organism
- Homo sapiens
- Partner
- ACKR2 View partner entry
- Partner description
- UniProt: O00590; Gene: ackr2_human; Family: Chemokine
- Interactions detected
- 83
3D VIEW
Model confidence legend
- Very high confidence (pLDDT > 90)
- High confidence (70 ≤ pLDDT < 90)
- Low confidence (50 ≤ pLDDT < 70)
- Very low confidence (pLDDT < 50)
RESIDUE CONTACTS
Residues are ordered by chemokine position and interaction type. Use the viewer controls to highlight contacting residues.
Download contacts (CSV)| Chemokine residue | CCN | Partner residue | GPCRdb generic | Interaction |
|---|---|---|---|---|
| GLN 1 | NTc.Cm29 | TRP 102 | 2.60x60 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TRP 102 | 2.60x60 | VdWContact |
| GLN 1 | NTc.Cm29 | TYR 124 | 3.32x32 | Hydrophobic |
| GLN 1 | NTc.Cm29 | TYR 124 | 3.32x32 | VdWContact |
| GLN 1 | NTc.Cm29 | GLU 298 | 7.39x38 | Cationic |
| GLN 1 | NTc.Cm29 | GLU 298 | 7.39x38 | HBDonor |
| GLN 1 | NTc.Cm29 | GLU 298 | 7.39x38 | VdWContact |
| VAL 3 | NTc.Cm27 | ASN 194 | - | Hydrophobic |
| VAL 3 | NTc.Cm27 | ASN 194 | - | VdWContact |
| VAL 3 | NTc.Cm27 | HIS 196 | 45.51x51 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 41 | 1.27x27 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 42 | 1.28x28 | Hydrophobic |
| PHE 4 | NTc.Cm26 | VAL 42 | 1.28x28 | VdWContact |
| PHE 4 | NTc.Cm26 | ASP 291 | 7.32x31 | Hydrophobic |
| PHE 4 | NTc.Cm26 | ASP 291 | 7.32x31 | VdWContact |
| PHE 4 | NTc.Cm26 | LEU 294 | 7.35x34 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 295 | 7.36x35 | Hydrophobic |
| PHE 4 | NTc.Cm26 | GLN 295 | 7.36x35 | VdWContact |
| GLU 5 | NTc.Cm25 | LYS 38 | 1.24x24 | VdWContact |
| ASP 6 | NTc.Cm24 | LEU 35 | - | Hydrophobic |
| ASP 6 | NTc.Cm24 | CYS 36 | - | VdWContact |
| ASP 6 | NTc.Cm24 | ARG 37 | - | VdWContact |
| ASP 6 | NTc.Cm24 | LYS 38 | 1.24x24 | HBAcceptor |
| ASP 6 | NTc.Cm24 | LYS 38 | 1.24x24 | VdWContact |
| CYS 7 | NTc.Cm23 | LEU 35 | - | VdWContact |
| CYS 7 | NTc.Cm23 | CYS 36 | - | HBAcceptor |
| CYS 7 | NTc.Cm23 | CYS 36 | - | HBDonor |
| CYS 7 | NTc.Cm23 | CYS 36 | - | VdWContact |
| CYS 7 | NTc.Cm23 | LYS 38 | 1.24x24 | Anionic |
| CYS 7 | NTc.Cm23 | LYS 38 | 1.24x24 | VdWContact |
| CYS 8 | NTc.Cm22 | MET 34 | - | VdWContact |
| CYS 8 | NTc.Cm22 | LEU 35 | - | VdWContact |
| LEU 9 | NTc.Cm21 | MET 34 | - | HBDonor |
| LEU 9 | NTc.Cm21 | MET 34 | - | VdWContact |
| LEU 9 | NTc.Cm21 | CYS 36 | - | Hydrophobic |
| LEU 9 | NTc.Cm21 | CYS 284 | 7.25x24 | Hydrophobic |
| ALA 10 | NTc.Cm20 | MET 34 | - | Hydrophobic |
| TYR 11 | NTc.Cm19 | MET 34 | - | VdWContact |
| HIS 12 | NTc.Cm18 | LEU 28 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | LEU 28 | - | VdWContact |
| HIS 12 | NTc.Cm18 | VAL 31 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | VAL 31 | - | VdWContact |
| HIS 12 | NTc.Cm18 | MET 34 | - | Hydrophobic |
| HIS 12 | NTc.Cm18 | MET 34 | - | VdWContact |
| GLY 16 | NTc.Cm14 | TYR 24 | - | VdWContact |
| VAL 19 | NTc.Cm11 | TYR 24 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | LEU 28 | - | Hydrophobic |
| VAL 19 | NTc.Cm11 | LEU 28 | - | VdWContact |
| ARG 22 | NTc.Cm8 | SER 21 | - | HBDonor |
| ARG 22 | NTc.Cm8 | SER 21 | - | VdWContact |
| ARG 22 | NTc.Cm8 | TYR 25 | - | VdWContact |
| ARG 27 | NTc.Cm3 | ASN 188 | - | VdWContact |
| VAL 31 | CX.5 | PHE 199 | - | HBAcceptor |
| VAL 31 | CX.5 | PHE 199 | - | Hydrophobic |
| VAL 31 | CX.5 | PHE 199 | - | VdWContact |
| VAL 31 | CX.5 | THR 204 | 5.32x33 | Hydrophobic |
| VAL 31 | CX.5 | LYS 207 | 5.35x36 | Hydrophobic |
| SER 32 | cxb1.1 | ALA 197 | 45.52x52 | VdWContact |
| SER 32 | cxb1.1 | LYS 207 | 5.35x36 | VdWContact |
| GLY 33 | cxb1.2 | LYS 207 | 5.35x36 | HBAcceptor |
| GLY 33 | cxb1.2 | LYS 207 | 5.35x36 | VdWContact |
| SER 34 | cxb1.5 | LYS 38 | 1.24x24 | VdWContact |
| ASN 36 | cxb1.8 | LYS 207 | 5.35x36 | VdWContact |
| ASN 36 | cxb1.8 | ASP 277 | 6.62x62 | HBDonor |
| ASN 36 | cxb1.8 | ASP 277 | 6.62x62 | Hydrophobic |
| ASN 36 | cxb1.8 | ASP 277 | 6.62x62 | VdWContact |
| ILE 41 | cxb1.16 | LEU 35 | - | Hydrophobic |
| LEU 44 | B1.3 | TYR 25 | - | Hydrophobic |
| LEU 44 | B1.3 | LEU 28 | - | Hydrophobic |
| LYS 46 | B1.5 | TYR 25 | - | Hydrophobic |
| ARG 47 | B1.6 | ASP 26 | - | Cationic |
| ARG 47 | B1.6 | ASP 29 | - | Cationic |
| ARG 47 | B1.6 | ASP 29 | - | HBDonor |
| ARG 47 | B1.6 | ASP 29 | - | VdWContact |
| ARG 49 | b1b2.1 | TYR 25 | - | HBDonor |
| ARG 49 | b1b2.1 | TYR 25 | - | VdWContact |
| ARG 49 | b1b2.1 | LEU 28 | - | HBDonor |
| ARG 49 | b1b2.1 | LEU 28 | - | VdWContact |
| ARG 49 | b1b2.1 | ASP 29 | - | Cationic |
| ARG 49 | b1b2.1 | ASP 29 | - | VdWContact |
| LYS 50 | b1b2.2 | LEU 35 | - | Hydrophobic |
| LYS 50 | b1b2.2 | LEU 35 | - | VdWContact |
| VAL 51 | b1b2.3 | LEU 28 | - | Hydrophobic |
